Contact Testing of the Buccal Mucous Membrane for Stomatitis Venenata

Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products – part 4: Solidago virgaurea–Vitis vinifera

“…Clove oil used in the mouth, either as the diluted or undiluted oil applied to cavities in teeth to relieve toothache, or as an ingredient of a mouthwash or other form of oral medication, has been reported to cause adverse reactions in and around the mouth. Patch testing can be used to identify relevant allergens . Permanent local anaesthesia and anhidrosis developed in a patient who spilled clove oil on the face while trying to treat a carious tooth .…”

Langerhans cell surface densities in rat oral mucosa and human buccal mucosa

“…For man, contact hypersensitivity reactions occur not only on external skin but also in oral mucosa, specifically to dental prostheses and items of oral hygiene (25)(26)(27). In this circutnstanee, elicitation reactions and perhaps even immunization must occur through otal mucosa, a tissue which has been studied less extensively than body wall skin for its contribution to hypetsensitivity teaetions.…”

Etiological factors in the denture sore mouth syndrome: an investigation of 24 patients

“…In the literature, several methods of application of potential allergens are described: Delbeck (1934) used a piece of cottonwool drenched in the allergen solution and applied it to the mucosa for about 20 minutes. Goldman & Goldman (1944) used rubber suction caps. The time of application was about 20 to 30 minutes.…”