Construction of ternary Au@GO coupled with poly-l-ethionine nanocomposite as a robust platform for electrochemical recognition of uric acid in diabetic patients

Elangovan, Arumugam; Sudha, Karuppaiah; Jeevika, Alagan; Bhuvaneshwari, Chandran; Kalimuthu, Palanisamy; Balakumar, Vellaichamy

doi:10.1016/j.colsurfa.2020.125050

Cited by 8 publications

(5 citation statements)

References 52 publications

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“…Furthermore, it exhibits a wider dynamic linear range and lower detection limit, yet there is a lack of further studies on this combination for NHS detection in the existing literature. Metal oxide nanoparticles (NPs) have recently garnered significant attention in electrocatalysis due to their selectivity, 12 prolonged lifetime, 13 and high catalytic activity in preparation methods. 14 Cerium, being one of the rare catalytic metals, possesses two partially filled electron subshells (5d and 4f).…”

Section: Introductionmentioning

confidence: 99%

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Cerium Zirconium Oxide-Decorated Reduced Graphene Oxide Nanocomposite for Low Potential Voltammetric Detection of N-Hydroxysuccinimide

Chandran,

Ramasamy,

Ponnaiah

et al. 2024

ACS Appl. Nano Mater.

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The necessity for highly sensitive and precise methodologies for monitoring water quality and safety is imperative. The substantial health risks linked with Nhydroxysuccinimide (NHS) in water samples and its contact with the skin and eyes are noteworthy. Despite the utilization of numerous techniques for NHS analysis, the adoption of a rapid and uncomplicated electrochemical process has been infrequent. This article details the fabrication of an electrochemical NHS detection system using a cerium zirconium oxide (CZO)-doped reduced graphene oxide (rGO) nanocomposite. The CZO/ rGO nanocomposite was prepared through a straightforward method involving precipitation and sonication. Structural analysis of the CZO/rGO involved various techniques, including X-ray diffraction (XRD), high-resolution transmission electron microscopy (HR-TEM), Raman spectroscopy, field emission scanning electron microscopy (FE-SEM), elemental mapping, energy dispersive X-ray analysis (EDX), and X-ray photoelectron spectroscopy analysis (XPS). Crucial kinetic parameters, such as the effective surface area, were evaluated for CZO/rGO on the glassy carbon electrode (GCE). Additionally, the CZO/rGO/GCE showcased reduced charge transfer resistance (R ct = 99 Ω), exceptional electrochemical activity, a high electron transfer rate, and strong selectivity. This electrode demonstrated excellent electrochemical sensing capabilities for NHS, boasting an extremely low detection limit (0.045 μM) and heightened sensitivity of 0.020 μA μM −1 cm −2 . Demonstrating its potential for swiftly detecting NHS in river water, the CZO/rGO/GCE sensor achieved over 97% recovery. This approach is particularly well-suited for creating water pollution sensors in various sensing devices.

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Section: Introductionmentioning

confidence: 99%

“…Metal oxide nanoparticles (NPs) have recently garnered significant attention in electrocatalysis due to their selectivity, prolonged lifetime, and high catalytic activity in preparation methods . Cerium, being one of the rare catalytic metals, possesses two partially filled electron subshells (5d and 4f).…”

Section: Introductionmentioning

confidence: 99%

Cerium Zirconium Oxide-Decorated Reduced Graphene Oxide Nanocomposite for Low Potential Voltammetric Detection of N-Hydroxysuccinimide

Chandran,

Ramasamy,

Ponnaiah

et al. 2024

ACS Appl. Nano Mater.

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“…As UA coexists with many other biomolecules inside the human body, such as AA and DA, the main problem regarding its detection arises from the latter's interference with UA, whose concentration exceeds the concentration level of DA by a hundred times [2].…”

Section: Introductionmentioning

confidence: 99%

“…To overcome these difficulties, many studies have focused on synthesizing new materials which can be employed to modify electrodes, including binary [2] and ternary [2,3] nanocomposites based on carbon structures, CPs, and metallic NPs [4].…”

Section: Introductionmentioning

confidence: 99%

“…In order to increase the sensitivity, the ES is sometimes modified with metallic NPs, carbon nanotubes, carbon monoliths, quantum dots, graphene and its derivatives, and/or CPs [2]. According to the studies reported in the last 6 years, the most promising results for achieving the highest sensitive electrochemical signal on a modified electrode, with linear response in a large range of concentrations and the lowest limit of detection (LOD), turned out to be composites based on carbonic structures and CPs, decorated with metallic NPs [1,3,4].…”

Section: Introductionmentioning

confidence: 99%

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Functionalization of Graphene Derivatives with Conducting Polymers and Their Applications in Uric Acid Detection

2022

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In this article, we review recent progress concerning the development of sensorial platforms based on graphene derivatives and conducting polymers (CPs), alternatively deposited or co-deposited on the working electrode (usually a glassy carbon electrode; GCE) using a simple potentiostatic method (often cyclic voltammetry; CV), possibly followed by the deposition of metallic nanoparticles (NPs) on the electrode surface (ES). These materials have been successfully used to detect an extended range of biomolecules of clinical interest, such as uric acid (UA), dopamine (DA), ascorbic acid (AA), adenine, guanine, and others. The most common method is electrochemical synthesis. In the composites, which are often combined with metallic NPs, the interaction between the graphene derivatives—including graphene oxide (GO), reduced graphene oxide (RGO), or graphene quantum dots (GQDs)—and the CPs is usually governed by non-covalent functionalization through π–π interactions, hydrogen bonds, and van der Waals (VW) forces. The functionalization of GO, RGO, or GQDs with CPs has been shown to speed up electron transfer during the oxidation process, thus improving the electrochemical response of the resulting sensor. The oxidation mechanism behind the electrochemical response of the sensor seems to involve a partial charge transfer (CT) from the analytes to graphene derivatives, due to the overlapping of π orbitals.

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Fabrication of cobalt tungstate/N-rGO nanocomposite: Application towards the detection of antibiotic drug-Furazolidone

Chandran

Elangovan

Chandrasekaran

et al. 2023

Colloids and Surfaces A: Physicochemical and Engineering Aspect

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Construction of ternary Au@GO coupled with poly-l-ethionine nanocomposite as a robust platform for electrochemical recognition of uric acid in diabetic patients

Cited by 8 publications

References 52 publications

Cerium Zirconium Oxide-Decorated Reduced Graphene Oxide Nanocomposite for Low Potential Voltammetric Detection of N-Hydroxysuccinimide

Cerium Zirconium Oxide-Decorated Reduced Graphene Oxide Nanocomposite for Low Potential Voltammetric Detection of N-Hydroxysuccinimide

Functionalization of Graphene Derivatives with Conducting Polymers and Their Applications in Uric Acid Detection

Fabrication of cobalt tungstate/N-rGO nanocomposite: Application towards the detection of antibiotic drug-Furazolidone

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