Construction of carbon dots/metal–organic framework composite for ratiometric sensing of norfloxacin

Wu, Shixin; Chen, Chun; Li, Wei; Sun, Mei; Zhuang, Jiechun; Lin, Junjie; Liu, Yingliang; Xu, Hong; Zheng, Mingtao; Zhang, Xuejie; Lei, Bingfu; Zhang, Haoran

doi:10.1039/d2tc03414j

Cited by 25 publications

(8 citation statements)

References 52 publications

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“…Interference arises because of the existence of several metal ions, including Fe 3+ , Ca 2+ , K + , Mg 2+ , and Cu 2+ , which can interfere with the NOR sensing capability inside a complex system. 14 Figure 4a depicts the precise identification of several ions and common biomolecules, such as NaCl, CaCl 2 , KCl, MgCO 3 , FeCl 3 , ZnNO 3 , urea, ascorbic acid, glucose, and glycine. The spectral study showed that the fluorescence sensor has specific sensitivity to NOR compared to other ions.…”

Section: Fluorescence Sensing Of Normentioning

confidence: 99%

Understanding Norfloxacin’s Turn-On Detection Mechanism: Focusing on Amorphous Carbon-Coated Iron Oxide Nanoparticles

Kumari,

Kadian,

Kumar

et al. 2024

ACS Appl. Opt. Mater.

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The excessive utilization of antibiotics poses a significant risk to worldwide human health, underscoring the pressing requirement for sustainable and nonhazardous approaches to detect antibiotics. Accordingly, we created a fluorescent probe that possesses a core−shell structure, which has been meticulously engineered for detecting antibiotics. Our developed probe utilizes amorphous carbon-coated iron oxide nanoparticles (C-IONs) to detect norfloxacin (NOR) with remarkable sensitivity. NOR greatly enhances the fluorescence of C-IONs, rendering it a very efficient pH-responsive sensor. By optimizing the synthesis and experimental parameters, we have effectively established a direct correlation between the fluorescence of C-IONs and the concentration of NOR within the range 0−10 μM. The achieved limit of detection (LOD) is 5.07 μM. C-IONs displayed outstanding morphology, stability, and notable specificity and selectivity toward NOR. The NOR detection in human blood serum yielded recovery rates between 95.1 and 99.5%, with a standard deviation of less than 1.31%. Therefore, the study confirms the efficacy of enhancing the practicality of using carbon-coated metal oxides for fluorescence-based antibiotic detection in actual samples.

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Section: Fluorescence Sensing Of Normentioning

confidence: 99%

Understanding Norfloxacin’s Turn-On Detection Mechanism: Focusing on Amorphous Carbon-Coated Iron Oxide Nanoparticles

Kumari,

Kadian,

Kumar

et al. 2024

ACS Appl. Opt. Mater.

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“…18 It can be served as a platform role to bind different fluorescent substances including organic dye molecules and quantum dots to fabricate dual-emission chemosensors. 19 Lanthanide metal organic frameworks have been extensively developed as the fluorescent probes owing to their excellent optical properties, and the abundant carboxyl groups on the surface of UiO-66-(COOH) 2 that can coordinate with lanthanide ions such as Eu 3+ , Tb 3+ , and Ce 3+ to exhibit characteristic luminescence via the antenna effect. 20 In this work, we propose the construction of a dual-emission ratiometric fluorescent nanoprobe for detecting HOCl based on Eu 3+ -modified and carbon dot-encapsulated MOFs.…”

Section: ■ Introductionmentioning

confidence: 99%

Selective Determination of HOCl in Environmental Water Samples and Real-Time Detection of HOCl Levels in Live Cells via Ratio Fluorescence Imaging Based on Eu³⁺-Modified and Carbon Dot-Encapsulated Metal Organic Frameworks

Zhang,

Tong

2024

ACS Appl. Nano Mater.

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Hypochlorous acid (HOCl) is one kind of significant ROS and a typical environmental pollution, which is closely linked to our food chain and threatens human health. Hence, a dual-emission ratiometric fluorescent nanoprobe (N-CDs@Eu-UiO-66-(COOH)2) for sensitive and specific determination of HOCl was fabricated based on Eu3+-modified and carbon dot-encapsulated MOFs. The N-CDs were encapsulated into MOFs, which can greatly improve their photostability and resistance to photobleaching in aqueous solution. The N-CDs@UiO-66-(COOH)2 was modified by Eu3+ ions, which can emit the red characteristic fluorescence of Eu3+ ions via the antenna effect. HOCl can quench the fluorescence of N-CDs through oxidizing hydroxyl groups on its surface, while the characteristic fluorescence of Eu3+ remains unchanged. The ratiometric fluorescence nanoprobe of N-CDs@Eu-UiO-66-(COOH)2 was thus fabricated for detecting HOCl. The nanoprobe has high sensitivity and selectivity, and its LOD (3σ/K) can attain 15.0 nM. Moreover, the N-CDs@Eu-UiO-66-(COOH)2 nanoprobe can also be applied for real-time detection of HOCl levels in the live cells via ratio fluorescence imaging, which can serve as a noninvasive tool for sensitively detecting fluctuations of HOCl levels in the living cells. This work can provide a promising application in environmental monitoring and real-time monitoring HOCl levels in vivo.

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“…As an emerging carbon nanomaterial, carbon dots (CDs) exhibit remarkable optical performance, which could emit fluorescence and phosphorescence with wavelength ranging from ultraviolet (UV) to near-infrared region. − They also possess multiple advantages, including facile synthesis, ease of functionalization, , excellent biocompatibility, low toxicity, , and chemical stability. These characteristics endow them with extensive application potentials in the fields of optoelectronic devices, , energy storage, sensing, ,, and drug delivery. , Despite that impressive research, CDs are also widely utilized in the synthesis of composites.…”

Section: Introductionmentioning

confidence: 99%

Tailoring Morphology and Fluorescence Properties of Zeolitic Imidazolate Frameworks via Carbon Dots

Li,

Wang,

et al. 2024

ACS Appl. Nano Mater.

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The assembly of carbon dots (CDs) and metal−organic frameworks (MOFs) into MOF@CDs composite materials is rapidly advancing in the field of nanoscience, driven by the potential to harness or enhance the advantages of both CDs and MOFs. However, the exploration of MOFs@CDs with controllable morphologies poses a considerable challenge. Herein, we present a universal synthetic strategy for zeolitic imidazolate frameworks (ZIFs)@CDs composite materials with tunable morphologies and solid-state fluorescence by modulating the surface structure of carbon dots and adjusting the reaction temperature. The assembly process of this strategy is mainly governed by the competitive coordination relationship between the surface functional groups of the carbon dots and the imidazole ligand and the zinc metal sources. Besides, the incorporation of ZIFs@CDs into sodium alginate (SA) to prepare a hydrogel (SA/ZIFs@CDs) effectively enabled the identification and adsorption of copper ions in which the 24-h adsorption capacity of SA/ZIF-L@CD 1 at an initial Cu 2+ concentration of 500 ppm could reach 200.53 mg g −1 . Moreover, the hydrogels dressing after adsorption of Cu 2+ could be used to resist the growth of Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus). This work provides insights for further advancements in structural design and a deeper understanding of the assembly behavior of the MOFs.

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Construction of carbon dots/metal–organic framework composite for ratiometric sensing of norfloxacin

Abstract: This fluorescent sensing material has the excellent optical properties of g-CDs and the selective detection and adsorption capability of UiO-66 for the target analyte; it determines the norfloxacin concentration via the F432/F530 fluorescence ratio.

Cited by 25 publications

References 52 publications

Understanding Norfloxacin’s Turn-On Detection Mechanism: Focusing on Amorphous Carbon-Coated Iron Oxide Nanoparticles

Understanding Norfloxacin’s Turn-On Detection Mechanism: Focusing on Amorphous Carbon-Coated Iron Oxide Nanoparticles

Selective Determination of HOCl in Environmental Water Samples and Real-Time Detection of HOCl Levels in Live Cells via Ratio Fluorescence Imaging Based on Eu³⁺-Modified and Carbon Dot-Encapsulated Metal Organic Frameworks

Tailoring Morphology and Fluorescence Properties of Zeolitic Imidazolate Frameworks via Carbon Dots

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Construction of carbon dots/metal–organic framework composite for ratiometric sensing of norfloxacin

Abstract: This fluorescent sensing material has the excellent optical properties of g-CDs and the selective detection and adsorption capability of UiO-66 for the target analyte; it determines the norfloxacin concentration via the F432/F530 fluorescence ratio.

Cited by 25 publications

References 52 publications

Understanding Norfloxacin’s Turn-On Detection Mechanism: Focusing on Amorphous Carbon-Coated Iron Oxide Nanoparticles

Understanding Norfloxacin’s Turn-On Detection Mechanism: Focusing on Amorphous Carbon-Coated Iron Oxide Nanoparticles

Selective Determination of HOCl in Environmental Water Samples and Real-Time Detection of HOCl Levels in Live Cells via Ratio Fluorescence Imaging Based on Eu3+-Modified and Carbon Dot-Encapsulated Metal Organic Frameworks

Tailoring Morphology and Fluorescence Properties of Zeolitic Imidazolate Frameworks via Carbon Dots

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Selective Determination of HOCl in Environmental Water Samples and Real-Time Detection of HOCl Levels in Live Cells via Ratio Fluorescence Imaging Based on Eu³⁺-Modified and Carbon Dot-Encapsulated Metal Organic Frameworks