2016
DOI: 10.1111/jpi.12340
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: The ubiquitin proteasome system has been proposed as a possible mechanism involved in the multiple actions of melatonin. COP1 (constitutive photomorphogenesis protein

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

0
27
0

Year Published

2016
2016
2022
2022

Publication Types

Select...
7
2

Relationship

1
8

Authors

Journals

citations
Cited by 37 publications
(27 citation statements)
references
References 122 publications
0
27
0
Order By: Relevance
“…A recent report regarding the possible involvement of 2‐hydroxymelatonin in the defense response against combined cold and drought stress suggested that melatonin metabolites play pivotal roles in plant growth and development as functional substances . Melatonin synthesis and catabolism are closely coupled to regulation of the levels of melatonin and its metabolites, all of which act as biostimulators or signaling molecules for a series of biological functions in plants, as well as acting as a health‐promoting molecule in humans . Further in‐depth studies on melatonin synthesis and regulation in plants will provide effective metabolic engineering strategies to generate melatonin‐rich transgenic crops and microbes, by either overexpressing the key melatonin biosynthetic genes or suppressing the negative regulatory genes for melatonin synthesis …”
Section: Discussionmentioning
confidence: 99%
“…A recent report regarding the possible involvement of 2‐hydroxymelatonin in the defense response against combined cold and drought stress suggested that melatonin metabolites play pivotal roles in plant growth and development as functional substances . Melatonin synthesis and catabolism are closely coupled to regulation of the levels of melatonin and its metabolites, all of which act as biostimulators or signaling molecules for a series of biological functions in plants, as well as acting as a health‐promoting molecule in humans . Further in‐depth studies on melatonin synthesis and regulation in plants will provide effective metabolic engineering strategies to generate melatonin‐rich transgenic crops and microbes, by either overexpressing the key melatonin biosynthetic genes or suppressing the negative regulatory genes for melatonin synthesis …”
Section: Discussionmentioning
confidence: 99%
“…The theory relating to melatonin and the proteasome system being involved in the anticancer actions of melatonin has recently been expanded to include a likely action on constitutive morphogenesis protein 1 (COP1) [217]. This theory also provides a context for melatonin’s antioxidant actions due to its potential interactions with the super complex formed by COP9, the oxidative stress sensor Keap1 and the deubiquitinase USP15 [217] (Figure 5).…”
Section: Melatonin and Cancer Progressionmentioning
confidence: 99%
“…This theory also provides a context for melatonin’s antioxidant actions due to its potential interactions with the super complex formed by COP9, the oxidative stress sensor Keap1 and the deubiquitinase USP15 [217] (Figure 5). …”
Section: Melatonin and Cancer Progressionmentioning
confidence: 99%
“…As such there is a rapidly growing body of knowledge examining the roles melatonin plays in plants, many of which employ controlled environment systems and in particular in vitro culture systems, many of which are helping to solidify the role of melatonin in plant processes. As both the receptors and mechanisms underlying the functions of melatonin in plants while an active area of research are still poorly understood, in vitro systems offer a valuable platform for their investigation (Lee and Back, 2016; Sanchez-Barcelo et al, 2016; Shi et al, 2016; Wei et al, 2016). One such important strategy, which has helped to confirm for example the importance of calcium signaling in melatonin responses in several species, is the inclusion of inhibitors in plant medium (Murch et al, 2001; Jones et al, 2007; Ramakrishna et al, 2009, 2011).…”
Section: Discussionmentioning
confidence: 99%