2020
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Abstract: The outbreak of the SARS‐CoV‐2‐induced coronavirus disease 2019 (COVID‐19) pandemic re‐shaped doctor‐patient interaction and challenged capacities of healthcare systems. It created many issues around the optimal and safest way to treat complex patients with severe allergic disease. A significant number of the patients are on treatment with biologicals, and clinicians face the challenge to provide optimal care during the pandemic. Uncertainty of the potential risks for these patients is related to the fact that… Show more

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“… 16 , 17 , 19 , 20 Additionally, eosinopenia has been observed in patients with COVID-19, and more prominently this was represented in the more severe cases, stabilizing after clinical improvement. 17 , 21 , 22 This suggests that eosinophils could play a protective role against developing more severe clinical outcomes. 21 , 22 …”
Section: How Does Covid-19 Affect Individuals With Asthma?mentioning
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“… 16 , 17 , 19 , 20 Additionally, eosinopenia has been observed in patients with COVID-19, and more prominently this was represented in the more severe cases, stabilizing after clinical improvement. 17 , 21 , 22 This suggests that eosinophils could play a protective role against developing more severe clinical outcomes. 21 , 22 …”
Section: How Does Covid-19 Affect Individuals With Asthma?mentioning
“… 17 , 21 , 22 This suggests that eosinophils could play a protective role against developing more severe clinical outcomes. 21 , 22 …”
Section: How Does Covid-19 Affect Individuals With Asthma?mentioning
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“…General recommendation suggests continuation of allergen immunotherapy in the current COVID-19 pandemic; however, the continuation rate of SCIT has low in Turkey during the COVID-19 pandemic [ 9 ]. Similarly, available international guidelines including the current EAACI statement recommend continuing biologicals for the treatment of asthma during COVID-19 and report that there is no current evidence to suggest that biologicals for the treatment of asthma increase the risk of CO­VID-19 infection; biological therapy was discontinued in one fourth of the asthma patients in our allergy clinics [ 10 ]. Internationally recommended adjustments for allergy and immunology practice can be applied to prevent this unnecessary discontinuation of therapeutic procedures including immunotherapy and biologics (Table 2 ) [ 10 , 11 ].…”
Section: Discussion/conclusionmentioning
“…Regarding treatment of severe allergic diseases with therapeutic proteins, a recent expert opinion article published by the European Academy of Allergy and Clinical Immunology suggested continuing them in otherwise healthy patients during the COVID-19 pandemic but pausing them in SARS -CoV-2-positive patients until they have recovered. 101…”
Section: Pediatricsmentioning