2004
DOI: 10.1001/archderm.140.11.1326
|View full text |Cite
|
Sign up to set email alerts
|

Connective Tissue Remodeling Induced by Carbon Dioxide Laser Resurfacing of Photodamaged Human Skin

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

7
179
4
2

Year Published

2004
2004
2017
2017

Publication Types

Select...
9
1

Relationship

4
6

Authors

Journals

citations
Cited by 149 publications
(193 citation statements)
references
References 26 publications
7
179
4
2
Order By: Relevance
“…While we observe a reduction of most CCN mRNA dermal levels during the initial step of hemostasis (first 2 days after wounding), it is interesting to note that CCN1 is upregulated at this time. These data are consistent with the observations that ECM protein production is reduced during the first week of wound repair (Orringer et al 2004) and with an anti-fibrotic function of CCN1 (Quan et al 2006) in human skin. CCN1 also induces angiogenesis in vitro and in vivo Lin et al 2003), and as Fig.…”
Section: Discussionsupporting
confidence: 92%
“…While we observe a reduction of most CCN mRNA dermal levels during the initial step of hemostasis (first 2 days after wounding), it is interesting to note that CCN1 is upregulated at this time. These data are consistent with the observations that ECM protein production is reduced during the first week of wound repair (Orringer et al 2004) and with an anti-fibrotic function of CCN1 (Quan et al 2006) in human skin. CCN1 also induces angiogenesis in vitro and in vivo Lin et al 2003), and as Fig.…”
Section: Discussionsupporting
confidence: 92%
“…MMP1 is called collagenase and its main substrate are collagen type III, I, II, VII, and X. Although it is well established that MMP expression was increased in damaged or photoaged skin [38,39], Cuerda-Galindo observed MMP-1 increased following IPL irradiation, consistent with the previous findings induced by laser treatment [40,41]. Based on the above theories, these authors speculate that increased MMP could be an overlooked mechanism of skin rejuvenation, in which it will be implicated, contributing to the degradation of senescent collagens and then the turnover of the ECM [35].…”
Section: In Vitro Effects Of Ipl On Fibroblasts Cytokines Etcsupporting
confidence: 79%
“…The clinical improvement occurs through a well-organized wound healing response leading to formation of new collagen [1]. Unfortunately, the clinical efficacy of ablative laser resurfacing has been limited by potential unwanted side effects and significant postoperative inconvenience [2,3].…”
Section: Introductionmentioning
confidence: 99%