Congenital self‐healing Langerhans cell histiocytosis: The need for a long term follow up

Diverse Cutaneous Presentations of Langerhans Cell Histiocytosis in Children: A Retrospective Cohort Study

“…Moreover, until now no histological characteristics specific for this self‐healing entity have been found . In accordance with other authors, we therefore prefer to omit the confusing term of CSHRH, at least if no reliable markers are delineated, and consider LCH to be a spectrum with more benign and more aggressive forms, but always requiring long‐term follow‐up …”

Neonatal Langerhans’ cell histiocytosis: a rare and potentially life‐threatening disease

“…Most cases of localized cutaneous LCH regress spontaneously 8,9 . However, progression to systemic involvement can occur years later, indicating that careful follow‐up with investigations, such as complete physical examination, full blood count, serum chemistry, liver function tests, and radiographic evaluation, is warranted 1,10 . Geissmann et al 11 .…”

Neonatal and Early Infantile Cutaneous Langerhans Cell Histiocytosis

“…28,[33][34][35] These relapses involved the skin, mucosa, bone, or pituitary gland and occurred when the infant was between ages 3 months and 4 years. In 1987, the Writing Group of the Histiocyte Society 1 suggested that the following minimum baseline studies should be performed: complete blood cell count, liver function tests, coagulation studies, chest radiography, skeletal surveys, and urine osmolality testing.…”