Congenital Heart Defects

Yagel, Simcha; Weissman, Ariel; Rotstein, Zeev; Manor, Moshe; Hegesh, Julius; Anteby, Eyal Y.; Lipitz, Shlomo; Achiron, R.

doi:10.1161/01.cir.96.2.550

Cited by 237 publications

(52 citation statements)

References 29 publications

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“…In our country, most fetal examinations are covered by major health insurance organizations. Fetal cardiac examination is standardized using the extended protocol for fetal echocardiography, as previously reported by us [6][7][8][9] . This routinely includes seven sonographic views: (1) transverse view of the upper abdomen; (2) four-chamber view; (3) longitudinal left outflow tract; (4) short-axis view for right outflow tract; (5) longitudinal view for aortic arch and ductus; (6) longitudinal view for systemic veins; and (7) upper axial mediastinal, three-vessel view combined with tracheal location for aortic arch abnormalities.…”

Section: Accepted 21-8-02 Ultrasound In Obstetrics and Gynecologymentioning

confidence: 99%

“…Various types of congenital aortic arch abnormalities have been described; however, most have been reported in the pediatric or radiological literature using magnetic resonance imaging (MRI) and spiral computed tomography (CT) [3][4][5] . Although current prenatal ultrasound technology facilitates identification of many congenital heart defects from early stages of gestation 6 , no information is available regarding aortic arch anomalies during fetal life. Because evaluation of aortic arch abnormalities requires clear definition of the fetal tracheal position in relation to the ductus arteriosus and the aortic arch, we utilized a novel sonographic approach to diagnose these abnormalities which, to the best of our knowledge, has never been reported previously.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Anomalies of the fetal aortic arch: a novel sonographic approach to in‐utero diagnosis

Achiron

Rotstein

Heggesh

et al. 2002

Ultrasound in Obstet & Gyne

149

150

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Section: Accepted 21-8-02 Ultrasound In Obstetrics and Gynecologymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Anomalies of the fetal aortic arch: a novel sonographic approach to in‐utero diagnosis

Achiron

Rotstein

Heggesh

et al. 2002

Ultrasound in Obstet & Gyne

149

150

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show abstract

“…A análise da influência da idade gestacional sobre o rastreamento das cardiopatias mostra que a taxa de detecção destas doenças, quando obtidas entre a 16ª e a 28ª semana, é 17% maior do que quando as análises são realizadas no primeiro trimestre, devido à existência de anomalias evolutivas 17 . No presente estudo, o resultado que obtivemos com idade gestacional média de 27 semanas pode ter sido determinado pela elevada taxa de sensibilidade do rastreamento e do ecocardiograma fetal em relação ao diagnóstico pós-natal.…”

Section: Discussionunclassified

Rastreamento e diagnóstico ecocardiográfico das arritmias e cardiopatias congênitas fetais

Carvalho¹,

Mendes²,

Cavalli³

et al. 2006

Rev. Bras. Ginecol. Obstet.

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RESUMOObjetivo: analisar os resultados obtidos em programa de rastreamento e diagnóstico de arritmias e cardiopatias congênitas centrado em uma unidade terciária e determinar a importância do diagnóstico precoce na evolução fetal e neonatal. Método: foram analisados os resultados da avaliação cardíaca fetal efetuada em 1159 gestantes em dois níveis diferentes. Nível I: uso da ultra-sonografia morfológica com o objetivo de rastrear a presença de alteração cardíaca, sem estabelecer um diagnóstico diferencial. Nível II: por ecocardiograma fetal com o objetivo de diagnosticar as cardiopatias fetais existentes. Os resultados da detecção de arritmias bem como da avaliação das alterações estruturais foram comparados, sendo estabelecidas a sensibilidade e a especificidade para ambos os níveis no pré-natal, ao exame pós-natal ou à necropsia. A concordância entre ambos os níveis foi calculada pelo índice kappa. Resultados: as arritmias detectadas no nível I foram confirmadas em todos os casos e não houve falso-negativos, sendo que em cinco pacientes houve necessidade de tratamento intra-útero. A detecção das alterações estruturais obtidas no nível I teve sensibilidade de 72% e especificidade de 98%, com 28% de falso-positivos. No nível II estes parâmetros foram, respectivamente, de 100 e 99%. De acordo com o coeficiente kappa de 57%, um grau de concordância de categoria moderada foi observado entre ambos os níveis. Das cardiopatias congênitas da nossa série 51% necessitaram intervenção farmacológica ou invasiva no período neonatal. Conclusão: o estudo ultra-sonográfico obstétrico é fundamental no rastreamento das alterações cardíacas fetais. O ecocardiograma fetal apresentou alto índice de sensibilidade e especificidade no diagnóstico das arritmias e cardiopatias congênitas, possibilitando o tratamento precoce das alterações graves. PALAVRAS-CHAVE: Cardiopatias congênitas; Diagnóstico pré-natal; Ecocardiografia/uso diagnóstico; Doenças fetais/ ultrasonografia; Cardiopatias congênitas/ultrasonografiaABSTRACT Purpose: to analyze the results of a screening and diagnostic program of arrhythmias and congenital heart disease in a reference hospital and the relevance of early diagnosis in the fetal and neonate evolution. Method: cardiac evaluation of 1159 fetuses was done in two different levels. Level I: by morphological ultrasound examination with the objective to detect the existence of either arrhythmias or structural cardiac malformations. Level II: by fetal echocardiography to establish the differential diagnosis. The results of level I in the arrhythmia group were compared with those of level II, and in the group with malformations the results of both levels were confronted with the neonate echocardiogram or necropsy. The kappa index was calculated to evaluate the concordance between the two levels. Results: all detected arrhythmias in level I were confirmed in level II, there were no false negative cases and five patients with severe arrhythmia required pharmacological therapy. The diagnosis of structural malformation by...

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“…Yagel et al 2 found that 64% of congenital heart defects are detectable during the first transvaginal scan at 13-16 weeks of gestation, and Moyano et al 3 demonstrated that heart malformations can be diagnosed reliably in the first trimester, at the time of nuchal translucency (NT) measurement.…”

Section: Non-invasive Prenatal Testing -It's All a Matter Of Timingmentioning

confidence: 99%

Non‐invasive prenatal testing – it's all a matter of timing

Zalel

2014

Ultrasound in Obstet & Gyne

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Congenital Heart Defects

Abstract: Although most fetal cardiac anomalies are detectable early in gestation, some may evolve in utero at different stages of pregnancy.

Cited by 237 publications

References 29 publications

Anomalies of the fetal aortic arch: a novel sonographic approach to in‐utero diagnosis

Anomalies of the fetal aortic arch: a novel sonographic approach to in‐utero diagnosis

Rastreamento e diagnóstico ecocardiográfico das arritmias e cardiopatias congênitas fetais

Non‐invasive prenatal testing – it's all a matter of timing

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