Congenital Anomalies of the Median Raphe

Wooldridge, Wilfred E.

doi:10.1001/archderm.1955.01540300035008

Cited by 13 publications

(6 citation statements)

References 3 publications

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“…The canals are lined by stratified squamous epithelium that does not communicate with the urethra [20]. The formation of the structure can be explained by two theories: the presence of epithelial residues at the site of incomplete genital fold closure and the migration of cell populations after genital fold closure [21][22][23]. There are two possible pathogeneses of gonococcal infection of the penile raphe [2].…”

Section: Discussionmentioning

confidence: 99%

Clinical Study on Gonococcal Infection of the Penile Raphe

Fan

Zhang²,

Wei

et al. 2023

Urol Int

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Introduction: Gonococcal infection of the penile raphe is rarely encountered in the clinical setting. The study aimed to understand the incidence, sites, clinical manifestations, and treatment of gonococcal infection of the penile raphe. Methods: We enrolled men with gonococcal infection of the penile raphe and men with urethral gonorrhea from January 2010 to December 2021. All patients’ demographic data and clinical characteristics were recorded. All patients were treated with ceftriaxone. Incision and drainage were performed in patients with non-ruptured abscesses. Nodules and sinus tract-like lesions that did not resolve after 1 month of treatment were excised. Results: Among 2,736 men who presented with urethral gonorrhea from January 2010 to December 2021, 5 (0.18%) had accompanying gonococcal infection of the penile raphe. An additional two men presented with gonococcal infection of the penile raphe without urethritis. Thus, 7 (0.26%; confidence interval, 0.11–0.56%) of 2,738 men had urethral gonorrhea or gonococcal infection of the penile raphe confirmed both clinically and by laboratory testing. Lesions were present in the frenulum of the prepuce and at the median aspect, proximal end, distal end, and both the proximal and distal ends of the penile raphe. The lesions manifested as abscesses, ulcers, a nodule, and a nodule with a sinus-like lesion. All lesions exhibited tenderness. All seven patients were cured after treatment. Conclusion: Gonococcal infection of the penile raphe is a rare, atypical type of involvement of the male urogenital tract by Neisseria gonorrhoeae. It may be a local complication of urethral gonorrhea or an independent primary infection. The proximal end, distal end, and median aspect of the penile raphe can be infected by N. gonorrhoeae. Cutaneous lesions present as abscesses, ulcers, nodules, and sinus-like lesions. Ceftriaxone is effective, but sinus-like lesions require surgery.

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Section: Discussionmentioning

confidence: 99%

Clinical Study on Gonococcal Infection of the Penile Raphe

Fan

Zhang²,

Wei

et al. 2023

Urol Int

View full text Add to dashboard Cite

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“…On the other hand, the cysts may be either ectodermal or endodermal in origin 2,4 . If there has been a secondary infection, only granulation tissue may be observed 5,7 …”

Section: Commentsmentioning

confidence: 99%

“…The treatment of choice is surgical excision, 2–7 although success with surgical drainage followed by electrocoagulation has also been reported 2,6 …”

Section: Commentsmentioning

confidence: 99%

“…The incidence of cases presenting these malformations is considerably more than would be expected. Although these afflictions were described in the last century, 1 very few cases have been published, and the majority have been reported by dermatovenereologists 2–7 …”

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confidence: 99%

“…Although these afflictions were described in the last century,' very few cases have been published, and the majority have been reported by dermatovenereologists. 2- 7 We have recently had the opportunity to observe a dysembryonic cyst of the penis, which was surgically treated with excellent results.…”

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confidence: 99%

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