Conducting Polymers: A Versatile Material for Biomedical Applications

Mattam, Liya Benny; Bijoy, Anusha; Thadathil, Ditto Abraham; George, Louis; Varghese, Anitha

doi:10.1002/slct.202201765

Cited by 14 publications

(8 citation statements)

References 157 publications

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“…Advances in conducting polymer technology have paved the path for all-polymer electronic components and circuits ( De Gans et al, 2023 ). Conductive polymer coatings can improve the electrical performance of brain recording and stimulation electrodes by lowering the interfacial impedance and improving the charge transfer density ( Benny Mattam et al, 2022 ). Because of their unique polymeric nature as well as favorable electrical and mechanical properties, stability, and biocompatibility, conducting polymers, a class of polymers with intrinsic electrical conductivity, have been one of the most promising materials in applications such as flexible electronics ( Someya et al, 2016 ) and bioelectronics ( Yuk et al, 2019 ).…”

Section: Printable Materials For Neural Device Fabricationmentioning

confidence: 99%

Printable devices for neurotechnology

Matta,

Moreau,

O’Connor

2024

Front. Neurosci.

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Printable electronics for neurotechnology is a rapidly emerging field that leverages various printing techniques to fabricate electronic devices, offering advantages in rapid prototyping, scalability, and cost-effectiveness. These devices have promising applications in neurobiology, enabling the recording of neuronal signals and controlled drug delivery. This review provides an overview of printing techniques, materials used in neural device fabrication, and their applications. The printing techniques discussed include inkjet, screen printing, flexographic printing, 3D printing, and more. Each method has its unique advantages and challenges, ranging from precise printing and high resolution to material compatibility and scalability. Selecting the right materials for printable devices is crucial, considering factors like biocompatibility, flexibility, electrical properties, and durability. Conductive materials such as metallic nanoparticles and conducting polymers are commonly used in neurotechnology. Dielectric materials, like polyimide and polycaprolactone, play a vital role in device fabrication. Applications of printable devices in neurotechnology encompass various neuroprobes, electrocorticography arrays, and microelectrode arrays. These devices offer flexibility, biocompatibility, and scalability, making them cost-effective and suitable for preclinical research. However, several challenges need to be addressed, including biocompatibility, precision, electrical performance, long-term stability, and regulatory hurdles. This review highlights the potential of printable electronics in advancing our understanding of the brain and treating neurological disorders while emphasizing the importance of overcoming these challenges.

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Section: Printable Materials For Neural Device Fabricationmentioning

confidence: 99%

Printable devices for neurotechnology

Matta,

Moreau,

O’Connor

2024

Front. Neurosci.

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“…Many CPs (such as PTh and PPy) are not naturally biodegradable [7,9,132]; however, they can be made biodegradable using a variety of techniques [38,46,133]. The first method involves combining conductive polymers with a biodegradable polymer to synthesize a composite [134,135].…”

Section: Biodegradabilitymentioning

confidence: 99%

Revolutionizing Drug Delivery and Therapeutics: The Biomedical Applications of Conductive Polymers and Composites-Based Systems

et al. 2023

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The first conductive polymers (CPs) were developed during the 1970s as a unique class of organic substances with properties that are electrically and optically comparable to those of inorganic semiconductors and metals while also exhibiting the desirable traits of conventional polymers. CPs have become a subject of intensive research due to their exceptional qualities, such as high mechanical and optical properties, tunable electrical characteristics, ease of synthesis and fabrication, and higher environmental stability than traditional inorganic materials. Although conducting polymers have several limitations in their pure state, coupling with other materials helps overcome these drawbacks. Owing to the fact that various types of tissues are responsive to stimuli and electrical fields has made these smart biomaterials attractive for a range of medical and biological applications. For various applications, including the delivery of drugs, biosensors, biomedical implants, and tissue engineering, electrical CPs and composites have attracted significant interest in both research and industry. These bimodalities can be programmed to respond to both internal and external stimuli. Additionally, these smart biomaterials have the ability to deliver drugs in various concentrations and at an extensive range. This review briefly discusses the commonly used CPs, composites, and their synthesis processes. Further highlights the importance of these materials in drug delivery along with their applicability in various delivery systems.

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“…In their pure form, conjugate polymers function as an insulator for a semiconductor, and the conductivity increases with dopant concentration. 160…”

Section: Nanomaterials For Mfc Cathode Electrodesmentioning

confidence: 99%