2021
DOI: 10.1007/s11606-021-06662-3 View full text |Buy / Rent full text
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Abstract: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.

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“…In the rare instances in which such elevated dosages are required for children and young adults (eg, cancer pain), interventions to mitigate overdose risk should be considered, such as coprescribing naloxone. 34 Moreover, 4.6% of opioid prescriptions dispensed to adolescents and young adults overlapped with a benzodiazepine prescription. In this population, benzodiazepines have limited evidence of efficacy for anxiety, the most common indication for these medications.…”
Section: Discussionmentioning
“…16 times higher than generic naloxone($8.16). However, among the uninsured population, the mean OOP cost per claim of Evzio was $1089.17 (95% CI, $884.17-$1294.17), compared with $73.62 (95% CI, $69.24-$78.00) per Narcan claim and $67.99 (95% CI, $61.42-$74.56) per generic naloxone claim.…”
mentioning
“…15 Despite guidelines promoting opioid/naloxone coprescribing, naloxone prescribing rates are low (below 3%) even for those receiving long-term opioid therapy. 16 Although there has been considerable attention on the legal barriers to naloxone distribution, far less attention has been given to the financial barriers of expanding access, particularly to individuals (carriers) likely to be in a position to help someone who has overdosed. The out-of-pocket (OOP) cost of naloxone is an important determinant of access, and there is evidence that naloxone demand responds to price.…”
Section: Introductionmentioning
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“…Individuals should be counseled that an increase in dosing may be required due to the physiology of pregnancy 48,53 . We recommend all buprenorphine prescriptions be provided with education on and a prescription for naloxone for overdose prevention 60 .…”
Section: Outpatient Initiation Of Buprenorphinementioning