Conceptual design of a dual reactive dividing wall column for downstream processing of lactic acid

Pazmiño-Mayorga, Isabel; Jobson, Megan; Kiss, Anton A.

doi:10.1016/j.cep.2021.108402

Cited by 13 publications

(3 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For chemical systems with nonidealities and strong interactions between acids in the vapor phase, the UNIQUAC-HOC and NRTL-HOC property models are sufficient. The UNIQUAC-HOC model was used to avoid introducing additional factors that might affect the comparison with previously published benchmark studies. , For a representative broth obtained from a bioprocess producing lactic acid, the feeding conditions to the reactive distillation are displayed in Table . It is important to mention that this is a simplified case study to test the feasibility of these structures.…”

Section: Case Studymentioning

confidence: 99%

Innovative Reactive Distillation Process for the Sustainable Purification of Lactic Acid

González-Navarrete

Sánchez‐Ramírez

Ramírez‐Márquez

et al. 2021

Ind. Eng. Chem. Res.

View full text Add to dashboard Cite

Lactic acid is commonly used in a wide range of fields, such as cosmetics, pharmaceutical products, chemistry, and food. During recent years, its use for new applications, such as the production of biodegradable and biocompatible polymers, green solvents, and oxygenated chemicals, have received considerable attention. However, the relatively high production cost of lactic acid hinders many large-scale applications. It is necessary to develop more efficient methods of separation and purification to cheapen lactic acid production processes. The main objective of this study is to investigate the use of process intensification, particularly the reactive distillation process, for a sustainable purification of lactic acid. To do so, there have been proposed, on the one hand, four intensified alternatives in which synthesis and design are based on thermal couplings and, on the other hand, three alternatives looking for water mass integration. Design and optimization of those modified configurations are carried out employing a stochastic optimization method, using as objective functions some metrics associated with the concept of sustainability (economics, environmental, and inherent safety indexes). A study on the dynamic performance of the configurations through the use of singular value decomposition is carried out in a complementary way. The results in the first redesign stage show improvements in all performance indexes. However, a great difference between the implementation of a thermal coupling that substitutes a condenser instead of a reboiler has been identified. The best scheme, based on a sustainability framework, resulted in a modified process, including a dividing wall column-based scheme.

show abstract

Section: Case Studymentioning

confidence: 99%

Innovative Reactive Distillation Process for the Sustainable Purification of Lactic Acid

González-Navarrete

Sánchez‐Ramírez

Ramírez‐Márquez

et al. 2021

Ind. Eng. Chem. Res.

View full text Add to dashboard Cite

show abstract

“…Daniel et al 174 applied the boundary value method (compositions set at the ends of the column) for the conceptual design of an R-DWC. Pazmiño-Mayorga et al 175 used a decomposition approach for the conceptual design of a dual R-DWC, where two reactionsesterification and hydrolysistake place in the same column.…”

Section: Reactive Dividing Wall Columnmentioning

confidence: 99%

Conceptual methods for synthesis of reactive distillation processes: recent developments and perspectives

Kiss,

Muthia,

Pazmiño‐Mayorga

et al. 2024

J of Chemical Tech & Biotech

Self Cite

View full text Add to dashboard Cite

Reactive distillation (RD) is a process intensification technique that offers major advantages over conventional technologies by enabling the integration of reaction and separation into a single apparatus. This integration introduces and exploits complex interaction between mass transfer, chemical reaction and hydrodynamics within an RD column; however, these complexities can hinder the adoption of reactive distillation by industry.Many approaches were developed by the scientific community to advance understanding and to expedite the initialization of RD design at the conceptual level. This paper critically discusses recent developments in conceptual methods for synthesizing RD processes. This review paper is the first to consider the range of available approaches for assessing the technical feasibility, controllability, economic viability, and sustainability, of RD units by taking into account various configurations in which RD is treated as a new unit operation, and as part of process synthesis in a different way of designing processes based on functions. The review also addresses complex configurations, such as advanced RD technologies. Special attention is paid to process modeling and simulation as well as to education. Knowledge gaps to be filled by further research are indicated.This article is protected by copyright. All rights reserved.

show abstract

“…For example, simulation studies found that R-DWC and thermally coupled arrangements are advantageous in terms of energy use when compared to conventional RD. , In addition, our previous conceptual design study helped identify the benefits of a dual R-DWC by using detailed kinetics for the main and side reactions in a rigorous simulation. The configuration improved energy use, material intensity, and water consumption . MA-RD could be used but with no specific advantage, except for the case where an azeotrope needs to be dealt with and if a suitable membrane exists.…”

Section: Case Studies To Demonstrate the Application Of The Synthesis...mentioning

confidence: 99%

A Systematic Methodology for the Synthesis of Advanced Reactive Distillation Technologies

Pazmiño-Mayorga

Jobson

Kiss

2023

Ind. Eng. Chem. Res.

Self Cite

View full text Add to dashboard Cite

This study is the first to provide a systematic approach to assessing the potential of advanced reactive distillation technologies to expand the applicability of reactive distillation. The work presented here focuses on the synthesis of advanced reactive distillation technologies, proposing a conceptually based methodology for earlystage screening. The methodology uses basic thermodynamic and kinetic data to navigate a decision-making flowchart in four steps: compositions and splits, basic properties and operating windows, kinetics, and phase equilibria. The results qualify advanced reactive distillation technologies as advantageous, technically feasible, or not applicable. Five industrially relevant case studies illustrate the application of the methodology to develop preliminary process flowsheets. The proposed methodology aims to guide technology selection using basic data while providing flexibility to meet the objectives of the design problem. This methodology contributes to integrating a technology-oriented approach normally followed in process intensification studies into a process systems engineering approach by developing a conceptual flowsheet in the early stages of process design.

show abstract

Conceptual design of a dual reactive dividing wall column for downstream processing of lactic acid

Cited by 13 publications

References 40 publications

Innovative Reactive Distillation Process for the Sustainable Purification of Lactic Acid

Innovative Reactive Distillation Process for the Sustainable Purification of Lactic Acid

Conceptual methods for synthesis of reactive distillation processes: recent developments and perspectives

A Systematic Methodology for the Synthesis of Advanced Reactive Distillation Technologies

Contact Info

Product

Resources

About