“…[8,9] Radiological features alone are inadequate to differentiate pyogenic brain abscess from fungal, nocardial or tuberculous abscess, inflammatory granuloma (tuberculoma), neurocysticercosis, toxoplasmosis, metastasis, glioma, resolving haematoma, infarct, hydatid cyst lymphoma and radionecrosis. [27][28][29][30] However, fever, meningism, raised ESR, multilocularity, leptomeningeal or ependymal enhancement, reduction of ring enhancement in delayed scan and finding of gas within the lesion favor a diagnosis of abscess. [9] Positive labeling in radionuclide imaging with III-Indium labeled leukocytes, C-reactive protein, 99m TC-hexamethylpropylene amine oxime leukocyte scintigraphy, diffusion weighted MRI, Thallium-201 GCS: Glasgow Coma Scale single photon emission CT, and proton MRS are helpful in differentiating abscess from tumor.…”