2016
DOI: 10.1155/2016/2073076
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Computer-Assisted Classification Patterns in Autoimmune Diagnostics: The AIDA Project

Abstract: Antinuclear antibodies (ANAs) are significant biomarkers in the diagnosis of autoimmune diseases in humans, done by mean of Indirect ImmunoFluorescence (IIF) method, and performed by analyzing patterns and fluorescence intensity. This paper introduces the AIDA Project (autoimmunity: diagnosis assisted by computer) developed in the framework of an Italy-Tunisia cross-border cooperation and its preliminary results. A database of interpreted IIF images is being collected through the exchange of images and double … Show more

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Cited by 21 publications
(18 citation statements)
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“…As mentioned in [39], the classification accuracy and mean class accuracy (MCA) are used to evaluate the performance of the algorithm. CCR k is first defined as the correct classification rate for class k, as shown in Eq.…”
Section: Performance Measurementsmentioning
confidence: 99%
“…As mentioned in [39], the classification accuracy and mean class accuracy (MCA) are used to evaluate the performance of the algorithm. CCR k is first defined as the correct classification rate for class k, as shown in Eq.…”
Section: Performance Measurementsmentioning
confidence: 99%
“…To evaluate the performance of a binary segmentation method, the accuracy metric has been the most commonly used in literature. However, because accuracy metric is low sensitive to imbalanced classes, in this work the metrics of mean class accuracy [20], sensitivity, specificity, positive predictive value, and Dice similarity coefficient are also employed to evaluate the segmentation performance of the proposed method. The six metrics are in the range [0, 1].…”
Section: Performance Evaluationmentioning
confidence: 99%
“…Elgaaied Benammar et al [24] have optimized and tested a CAD system on HEp-2 images which is able to recognize seven fluorescence patterns. The system searches and classifies positive and negative mitosis, within the image; the classification of mitosis occurs by using two neural network classifiers, the final decision-making process for the detection of fluorescence pattern is achieved by using a K-Nearest Neighbors classifier.…”
Section: Related Workmentioning
confidence: 99%
“…The development of a CAD system is intimately linked to a data collection. In this work the dataset provided by the AIDA (AutoImmunité, Diagnostic Assisté par ordinateur) project [24] was used. In this project, using a uniform approach, seven immunology services (three Tunisian and four Sicilian) contributed to collect images of the IIF test on HEp-2 cells.…”
Section: Databasementioning
confidence: 99%