2017
DOI: 10.1177/0037549717712603
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Abstract: Bileaflet mechanical heart valves (BMHVs) are widely used to replace diseased heart valves. However, patients may suffer from implant complications, such as platelet aggregation and damage to blood cells, which could lead to BMHV failure. These complications are related to the blood flow patterns in the BMHV. A three-dimensional computational fluid dynamic (CFD) model was developed to investigate blood hydrodynamics and shear stresses at different cardiac cycles. A user-defined function (UDF) code was develope… Show more

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Cited by 22 publications
(17 citation statements)
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“…Optimization of the design of mechanical valves is achieved using computational and experimental methods [9][10][11] to improve the velocity profiles and minimize the complications that are caused by prosthetics. Modern numerical simulation methods such as DNS, URANS, LES, and DES are used for calculations [12][13][14].…”
Section: Methodsmentioning
confidence: 99%
“…Optimization of the design of mechanical valves is achieved using computational and experimental methods [9][10][11] to improve the velocity profiles and minimize the complications that are caused by prosthetics. Modern numerical simulation methods such as DNS, URANS, LES, and DES are used for calculations [12][13][14].…”
Section: Methodsmentioning
confidence: 99%
“…Bileaflet mechanical heart valve (BMHV) shown in Figure is the most preferred prosthetic replacement to the native aortic valve; however, the thromboembolic complications associated with BMHV still remain a major concern . BMHVs generate non‐physiological blood flow patterns characterized by high shear stresses, shed vortices, and recirculation of blood . Such flow patterns cause platelets to activate, which aggregate to form a blood clot (thrombosis) …”
Section: Introductionmentioning
confidence: 99%
“…Computational investigation of the blood flow in artificial organs and biomedical devices such as heart pumps in various designs has equally attracted attention . A further field where CFD approaches have been extensively utilized comprises design engineering and performance monitoring of heart valves …”
Section: Introductionmentioning
confidence: 99%
“…[12][13][14][15] A further field where CFD approaches have been extensively utilized comprises design engineering and performance monitoring of heart valves. [16][17][18][19] One of the early CFD analyses of oxygenators (including the membrane and the hardshell reservoir) is due to Gage et al, 20 who investigated a commercial membrane oxygenator computationally and experimentally, with emphasis on the pressure drop. A Newtonian behavior for the blood was assumed, along with the assumption of a laminar flow.…”
Section: Introductionmentioning
confidence: 99%