Compositional studies and antioxidant potential of Albizia lebbeck (L.) Benth. pods and seeds

Zia-Ul-Haq, Muhammad; Ahmad, Shakeel; Qayum, Mughal; Erċışlı, Sezai

doi:10.3906/biy-1204-38

Cited by 15 publications

(4 citation statements)

References 28 publications

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“…The other oils contained mainly α- and γ-T in varying proportion, with most of the oils containing more α-T than γ-T except for D. latifolia , which contained almost exclusively γ-T. A previous investigation of A. lebbeck seed oil reported a much smaller tocopherol concentration (84.93 mg 100 g −1 ) and a different tocopherol profile. The proportion of α-T was larger, the γ-T was smaller and a higher β-T content and proportion was observed [ 42 ].…”

Section: Resultsmentioning

confidence: 99%

Evaluation of Selected Medicinal, Timber and Ornamental Legume Species’ Seed Oils as Sources of Bioactive Lipophilic Compounds

et al. 2023

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Bioactive lipophilic compounds were investigated in 14 leguminous tree species of timber, agroforestry, medicinal or ornamental use but little industrial significance to elucidate their potential in food additive and supplement production. The tree species investigated were: Acacia auriculiformis, Acacia concinna, Albizia lebbeck, Albizia odoratissima, Bauhinia racemosa, Cassia fistula, Dalbergia latifolia, Delonix regia, Entada phaseoloides, Hardwickia binata, Peltophorum pterocarpum, Senegalia catechu, Sesbania sesban and Vachellia nilotica. The hexane-extracted oils of ripe seeds were chromatographically analysed for their fatty acid composition (GC-MS), tocochromanol (RP-HPLC/FLD), squalene and sterol (GC-FID) content. A spectrophotometrical method was used to determine total carotenoid content. The results showed generally low oil yield (1.75–17.53%); the highest was from H. binata. Linoleic acid constituted the largest proportion in all samples (40.78 to 62.28% of total fatty acids), followed by oleic (14.57–34.30%) and palmitic (5.14–23.04%) acid. The total tocochromanol content ranged from 100.3 to 367.6 mg 100 g−1 oil. D. regia was the richest and the only to contain significant amount of tocotrienols while other oils contained almost exclusively tocopherols, dominated by either α-tocopherol or γ-tocopherol. The total carotenoid content was highest in A. auriculiformis (23.77 mg 100 g−1), S. sesban (23.57 mg 100 g−1) and A. odoratissima (20.37 mg 100 g−1), and ranged from 0.7 to 23.7 mg 100 g−1 oil. The total sterol content ranged from 240.84 to 2543 mg 100 g−1; A. concinna seed oil was the richest by a wide margin; however, its oil yield was very low (1.75%). Either β-sitosterol or Δ5-stigmasterol dominated the sterol fraction. Only C. fistula oil contained a significant amount of squalene (303.1 mg 100 g−1) but was limited by the low oil yield as an industrial source of squalene. In conclusion, A. auriculiformis seeds may hold potential for the production of carotenoid-rich oil, and H. binata seed oil has relatively high yield and tocopherol content, marking it as a potential source of these compounds.

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Section: Resultsmentioning

confidence: 99%

Evaluation of Selected Medicinal, Timber and Ornamental Legume Species’ Seed Oils as Sources of Bioactive Lipophilic Compounds

et al. 2023

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“…With the advancement of analytical technology, methods including stable isotope and multi-element analyses, liquid and gas chromatographic techniques, molecular biology methods and spectroscopic techniques have been applied in favor of food traceability over the last few decades [ 4 ]. Among them, stable isotope analysis (SIA) has become a common and relatively efficient analytical method for determining the geographical origins of foods.…”

Section: Introductionmentioning

confidence: 99%

Impact of Noodle Formulation, Boiling Methodology and Their Interactions on Stable Hydrogen and Oxygen Isotope Ratios

Yang,

Erasmus,

Sun

et al. 2024

Foods

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Stable isotopes are commonly utilized for the geographical origin verification of foods, including wheat. However, assessing processed products poses a greater challenge due to the alterations that take place during processing and which have not been fully elucidated yet. In the current study, the effects of the formulation (the mass ratios of gluten to starch), boiling process and their interaction on the stable hydrogen (δ2H) and oxygen (δ18O) isotopic ratios of wheat noodles were evaluated. The δ2H and δ18O of noodles with different formulations (the mass ratios of gluten to starch) as raw materials, in uncooked and cooked (boiled in water) noodles, were examined. The results indicated that the δ2H of the boiled noodles ranged from −80.1‰ to −46.8‰ and were significantly lower than those of the raw materials, which ranged from −73.0‰ to −39.2‰, and the uncooked noodles, which ranged from −73.3‰ to −39.6‰. Oppositely, 18O was enriched in the boiled noodles, ranging from 27.7‰ to 31.3‰, compared with the uncooked noodles, ranging from 28.4‰ to 29.6‰. In addition, a significant interaction effect between the formulation and the boiling process was recorded for δ18O. This study shows that the hydrogen and oxygen stable isotopic compositions of noodles were significantly changed during the boiling process, and the isotopic fractionation varies with the different formulations.

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“…The A. lebbeck flower from the Saudi Arabia region, extracted using dichloromethane with 71.6% yield, showed anti-inflammatory activity. This study suggests the use of the plant in treating inflammation and recommends isolating the components responsible for the anti-inflammatory activity [ 17 ]. Saponins are the major phytochemical constituents found on the flower of the plant, and the two types of saponins named lebbeckosides A and B isolated from revealed significant cytotoxic activity on glioblastoma stem-like TG1 human and glioblastoma U-87 MG cells lines.…”

Section: Introductionmentioning

confidence: 99%

Prediction of Cell Migration in MDA-MB 231 and MCF-7 Human Breast Cancer Cells Treated with Albizia Lebbeck Methanolic Extract Using Multilinear Regression and Artificial Intelligence-Based Models

Umar¹,

Rizaner

Usman³

et al. 2023

Pharmaceuticals

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Breast cancer is a common cancer affecting women worldwide, and it progresses from breast tissue to other parts of the body through a process called metastasis. Albizia lebbeck is a valuable plant with medicinal properties due to some active biological macromolecules, and it’s cultivated in subtropical and tropical regions of the world. This study reports the phytochemical compositions, the cytotoxic, anti-proliferative and anti-migratory potential of A. lebbeck methanolic (ALM) extract on strongly and weakly metastatic MDA-MB 231 and MCF-7 human breast cancer cells, respectively. Furthermore, we employed and compared an artificial neural network (ANN), an adaptive neuro-fuzzy inference system (ANFIS), and multilinear regression analysis (MLR) to predict cell migration on the treated cancer cells with various concentrations of the extract using our experimental data. Lower concentrations of the ALM extract (10, 5 & 2.5 μg/mL) showed no significant effect. Higher concentrations (25, 50, 100 & 200 μg/mL) revealed a significant effect on the cytotoxicity and proliferation of the cells when compared with the untreated group (p < 0.05; n ≥ 3). Furthermore, the extract revealed a significant decrease in the motility index of the cells with increased extract concentrations (p < 0.05; n ≥ 3). The comparative study of the models observed that both the classical linear MLR and AI-based models could predict metastasis in MDA-MB 231 and MCF-7 cells. Overall, various ALM extract concentrations showed promising an-metastatic potential in both cells, with increased concentration and incubation period. The outcomes of MLR and AI-based models on our data revealed the best performance. They will provide future development in assessing the anti-migratory efficacies of medicinal plants in breast cancer metastasis.

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Compositional studies and antioxidant potential of Albizia lebbeck (L.) Benth. pods and seeds

Cited by 15 publications

References 28 publications

Evaluation of Selected Medicinal, Timber and Ornamental Legume Species’ Seed Oils as Sources of Bioactive Lipophilic Compounds

Evaluation of Selected Medicinal, Timber and Ornamental Legume Species’ Seed Oils as Sources of Bioactive Lipophilic Compounds

Impact of Noodle Formulation, Boiling Methodology and Their Interactions on Stable Hydrogen and Oxygen Isotope Ratios

Prediction of Cell Migration in MDA-MB 231 and MCF-7 Human Breast Cancer Cells Treated with Albizia Lebbeck Methanolic Extract Using Multilinear Regression and Artificial Intelligence-Based Models

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