Complications of wound healing: causes and prevention

Abstract

Where the normal wound healing stages are interrupted or delayed, chronic or non-healing wounds develop. Wound healing complications may arise due to systemic and local factors. Knowledge of likely impediments to normal wound healing allows recognition and prevention of potentially problematic wounds.

A Case Series Analysis of Dental Extractions’ Outcome in Cats with Chronic Gingivostomatitis Carrying Retroviral Disease

“…FeLV-positive cats had significantly less proliferative stomatitis and less TR than control cases. Considering that wound healing is impaired in immunosuppressed cats [ 48 , 49 ], and FeLV can infect fibroblast precursor cells and interfere with fibroblast function [ 50 ], this could explain why oral lesions in this group are predominantly non-proliferative. The occurrence of TR was not positively associated with cats carrying FeLV infection, which meets the observations previously reported by other authors [ 51 , 52 ], where age is pointed as the main risk factor to the development of TR in cats.…”

The Wound Healing Potential of 2,3 Dimethylquinoxaline Hydrogel in Rat Excisional Wound Model

“…Wounds are defined as harm to the skin's structural integrity brought on by many causes such as burns, cuts, scalds, and lesions such as foot complications of diabetes [1]. Improper management of wounds is associated with many complications such as infections, wound dehiscence, inflammation, scarring, and improper angiogenesis and regeneration [2,3].…”

The activity of Aloe arborescens Miller varieties on wound-associated pathogens, wound healing and growth factor production

“…Each of these growth factors have overlapping functions in wound healing through the modulation of angiogenesis and cell migration (Barrientos et al, 2008;Lynch et al, 1989). Complications or imbalances with the wound healing process may lead to negative downstream effects such as chronic wounds or pathogenic infection (Aldridge, 2015). Bacterial infection may cause increased inflammation at or around the wound site causing excessive swelling, which may hinder the wound healing process (Aldridge, 2015).…”

“…Complications or imbalances with the wound healing process may lead to negative downstream effects such as chronic wounds or pathogenic infection (Aldridge, 2015). Bacterial infection may cause increased inflammation at or around the wound site causing excessive swelling, which may hinder the wound healing process (Aldridge, 2015). Adverse pathogenic infection of wounds may spread to deeper tissues of the body and may reach the bloodstream, causing bacteremia.…”