Complications of traditional Chinese/herbal medicines (TCM)—a guide for perplexed oncologists and other cancer caregivers

Chiu, Joanne; Yau, Thomas; Epstein, Richard J.

doi:10.1007/s00520-008-0526-x

Cited by 43 publications

(32 citation statements)

References 104 publications

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“…However, TCM treatment methods of HCC have some inherent disadvantages, such as the unobvious effect of some herbal medicines, unclear active ingredients of TCM, lack of treatment evaluation standards, and so on [101]. Therefore, below, we summarize the current problems and deficiencies in this field for the purpose of supplying guidance for the clinician to provide scientific medical treatments for HCC.…”

Section: Current Problems and Future Application Prospects Of Tcm Trementioning

confidence: 99%

Traditional Chinese medicine combined with other therapies for treatment of hepatocellular carcinoma in clinical trials

Feng¹,

Zhu²,

Hu³

et al. 2017

Cancer Rep Rev

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Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide with a high mortality, and still there are only few effective methods to treat it. To this end, alternative medicines from traditional Chinese medicine (TCM) are being investigated for their ability to eliminate the tumor or halt its progression. A large number of studies have shown that TCM can be an effective approach to treat the HCC in clinical trials when used alone or in combination with other therapies. Thus, TCM has made significant progress, and has begun to gain worldwide popularity for promoting healthcare and HCC treatment. Because of this progress, periodic summaries are needed to facilitate further research for the use of TCM to treat HCC. This paper provides a comprehensive summary of this work with regard to the following aspects: herbalist views on the etiology and therapeutic principles for treatment of HCC, treating HCC by TCM alone, treating HCC with TCM in combination with resection, chemotherapy, radiotherapy and interventional therapy, and other therapies. Additionally, the current main problems and future application prospects for treatment of HCC by TCM described, which could provide scientific guidance for clinician as well as references for the treatment of other cancers.

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Section: Current Problems and Future Application Prospects Of Tcm Trementioning

confidence: 99%

Traditional Chinese medicine combined with other therapies for treatment of hepatocellular carcinoma in clinical trials

Feng¹,

Zhu²,

Hu³

et al. 2017

Cancer Rep Rev

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“…An editorial in JAMA emphasizes that the fundamental issue is not traditional medicine versus alternative medicine, but medical practice supported by clinical and scientific evidence or not (Fontanarosa and Lundberg, 1998). In the case of CHM, since herbs are often administered as a decoction, i.e., as a combination of multiple herbs in which the individual constituents may be difficult to determine, their 'neither-proven-nor-disproven' medicinal status is likely to prove durable (Chiu et al, 2009). The scientific proof and clinical validation of CHM require a rigorous approach that includes chemical standardization, biological assays, animal studies and clinical trials.…”

Section: Introductionmentioning

confidence: 97%

MEDLINE-based assessment of animal studies on Chinese herbal medicine

Garcia¹,

García‐Bermejo²,

Martínez³

et al. 2012

Journal of Ethnopharmacology

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The recent decade witnessed an increase in CHM research activities and CHM English publications. Based on common problems identified in publications on CHM animal studies, we have proposed a checklist that could help in preliminary selection of publications lacking the most common problems and thus would be useful for a quick search of reproducible CHM regimens that are likely to be effective in a given context. The second application of this checklist is to help avoid the most common problems when designing experiments.

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“…Currently, there is a tremendous interest in the western world in TCM. TDDS of TCM using various carriers is an effective way to enhance the bioavailability of drug and improve their curative effect (Yang, 2004;Chiu et al, 2009;Parekh et al, 2009). TCM drugs could be concentrated directly to the organs, cells, lesion tissues or cell structures after the effective transmission by these carriers.…”

Section: Introductionmentioning

confidence: 99%

Application of traditional Chinese medicine preparation in targeting drug delivery system

Xing

Dong

et al. 2014

Drug Delivery

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(2015) Application of traditional Chinese medicine preparation in targeting drug delivery system, Drug Delivery, 22:3, 258-265, DOI: 10.3109/10717544.2014 AbstractTargeting drug system (TDS) or targeted drug delivery system (TDDS) is a new kind of drug delivery system which could make drug to be directly concentrated on the target site with high curative effects and low side-effects. As the quintessence of Chinese culture, traditional Chinese medicine (TCM) has a large advantage in many disease clinical treatments, especially in cancer, hypertension and many other intractable diseases owing to their low toxicity and side-effects relative to western medicine. This article reviews literatures on development of TCM-targeted preparations which were published in the past 10 years. TDS including active-targeting, passive-targeting and physical-chemical-targeting preparations were introduced through domestic and overseas literatures to reveal the unique advantages of TCM-targeting preparations in drug delivery system. In this article, we have reviewed some kinds of TCM-targeting preparations and indicated that great attention should be paid to the research on the TCM-targeting preparations.

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Complications of traditional Chinese/herbal medicines (TCM)—a guide for perplexed oncologists and other cancer caregivers

Abstract: Through sensitive understanding of the reasons favoring TCM usage, oncologists can gain the trust and respect of their TCM-using patients while ensuring the safety and efficacy of conventional anticancer treatments.

Cited by 43 publications

References 104 publications

Traditional Chinese medicine combined with other therapies for treatment of hepatocellular carcinoma in clinical trials

Traditional Chinese medicine combined with other therapies for treatment of hepatocellular carcinoma in clinical trials

MEDLINE-based assessment of animal studies on Chinese herbal medicine

Application of traditional Chinese medicine preparation in targeting drug delivery system

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