Complications of third-trimester amniocentesis using continuous ultrasound guidance

Gordon, Michael; Narula, Komal; O’Shaughnessy, R.; Barth, William H.

doi:10.1016/s0029-7844(01)01715-x

Cited by 43 publications

(30 citation statements)

References 7 publications

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“…Only five studies [9][10][11][12][13] have been published, but in only one [8] the indication was fetal karyotyping. In the other studies amniocentesis was performed to assess fetal lung maturity [10][11][12][13] and thus they would not be appropriate for comparison with our study. However, Piiroinen et al [10] performed 501 amniocenteses in 370 women and had a pPROM rate of 1.8% of cases within 24 h, without evidence of fetal damage or chorioamnionitis.…”

Section: Discussionmentioning

confidence: 99%

“…Fisk et al [8] and Shalev et al [9] were the first to describe late amniocentesis as an alternative for women who are unwilling to accept the risks of early fetal karyotyping in a small series of 3 [8] and 14 [9] women. However, the risks of amniocentesis for fetal karyotyping, performed in the third-trimester, are poorly described [8][9][10][11][12][13][14] .…”

Section: Introductionmentioning

confidence: 99%

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Fear of Pregnancy Loss and Fetal Karyotyping: A Place for Third-Trimester Amniocentesis?

et al. 2007

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Objective: To assess the complications of third-trimester amniocentesis for fetal karyotyping in women unwilling to accept the fetal loss risks of second-trimester amniocentesis. Methods: Retrospective study of singleton pregnancies that underwent a third-trimester amniocentesis for karyotyping. 150 complete charts between 1998 and 2005 were reviewed. Results: The indications were: isolated abnormal second-trimester biochemical markers (n = 57), isolated maternal age >38 years (n = 46), integrated risk (maternal age, first-trimester nuchal translucency, second-trimester maternal serum markers) >1/250 (n = 22), history of chromosomal abnormality (n = 17) or maternal choice (n = 8). The median maternal age and gestational age at sampling were: 40 years (23–48), 32.4 weeks (29.7–37.1). Median interval between amniocentesis, definitive result of amniocentesis, and delivery were 14 days (7–42), and 49 days (10–67) respectively. There were no abnormal karyotypes and no termination of pregnancy. Six women out of 150 (4%) had spontaneous labor before 36 weeks (2% after 36 weeks). Conclusion: The risk of spontaneous labor before 37 weeks after late amniocentesis is 4% (2% before 36 weeks). This technique provides a late but safe reassurance to women who are unwilling to accept the risks of earlier fetal karyotyping. This is of interest to countries such as France where legislation permits late termination of pregnancy.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Fear of Pregnancy Loss and Fetal Karyotyping: A Place for Third-Trimester Amniocentesis?

et al. 2007

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“…In conclusion, treatment with NSAID during the last trimester may increase the risk of adverse neonatal outcomes but may also be crucial in the palliative treatment of polyhydramnios and in delaying delivery in this condition. Third-trimester amniocentesis only involves low risk of complications when continuously guided by ultrasound [13] .…”

Section: Discussionmentioning

confidence: 99%

Acute Recurrent Polyhydramnios: A Combination of Amniocenteses and NSAID May Be Curative Rather than Palliative

Rode¹,

Bundgaard²,

Skibsted

et al. 2007

Fetal Diagn Ther

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Acute recurrent polyhydramnios is a rare occurrence characterized by a poor fetal outcome. This is a case report describing a 34-year-old woman presenting with acute recurrent polyhydramnios. Treatment with non-steroidal anti-inflammatory drugs (NSAID) and therapeutic amniocenteses was initiated immediately and resulted in a decreased amniotic fluid production from 30 weeks’ gestation. Even after the discontinuation of NSAID treatment, the amniotic fluid production normalized, and the woman delivered a healthy boy at 39 weeks 2 days’ gestation. Amniotic prolactin was measured at three occasions using an enzyme-linked immunosorbent assay. As in normal pregnancies, amniotic prolactin levels decreased by 80% from highest to lowest value in this case of resolving acute recurrent polyhydramnios.

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“…Complications due to amniocentesis have been reported in the first 48 h after the procedure that merit urgent resolution of pregnancy or before the completion of lung maturity. These include alterations in fetal heart rate, placental hemorrhage, placental abruption, uterine rupture, preterm labor and rupture of membranes [4,[9][10][11]. The total rate of pregnancy loss after amniocentesis varies from 0.3% to 11.2% [4,10,[12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Complications Associated With Amniocentesis in the Third Trimester of Pregnancy

Ramírez-Montiel¹,

Casillas-Barrera²,

Morales-Morales³

et al. 2017

J Clin Gynecol Obstet

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Complications of third-trimester amniocentesis using continuous ultrasound guidance

Abstract: Third-trimester amniocentesis performed with continuous ultrasound guidance has a high success rate and low risk for complications.

Cited by 43 publications

References 7 publications

Fear of Pregnancy Loss and Fetal Karyotyping: A Place for Third-Trimester Amniocentesis?

Fear of Pregnancy Loss and Fetal Karyotyping: A Place for Third-Trimester Amniocentesis?

Acute Recurrent Polyhydramnios: A Combination of Amniocenteses and NSAID May Be Curative Rather than Palliative

Complications Associated With Amniocentesis in the Third Trimester of Pregnancy

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