Complications after prostate biopsies in men on active surveillance and its effects on receiving further biopsies in the Prostate cancer Research International: Active Surveillance (PRIAS) study

Bokhorst, Leonard P.; Lepistö, Inari; Kakehi, Yoshiyuki; Bangma, Chris H.; Pickles, Tom; Valdagni, Riccardo; Alberts, Arnout R.; Semjonow, Axel; Strölin, Petra; Montesino, Manuel; Berge, Viktor; Roobol, Monique J.; Rannikko, Antti

doi:10.1111/bju.13410

Cited by 54 publications

(38 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Systematic biopsies currently appear one of the largest burdens for men on AS [4,15,16], and in fact they are redundant in three-quarters of men because they do not show reclassification (Fig. 1).…”

Section: Discussionmentioning

confidence: 99%

A Decade of Active Surveillance in the PRIAS Study: An Update and Evaluation of the Criteria Used to Recommend a Switch to Active Treatment

et al. 2016

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

A Decade of Active Surveillance in the PRIAS Study: An Update and Evaluation of the Criteria Used to Recommend a Switch to Active Treatment

et al. 2016

Self Cite

View full text Add to dashboard Cite

show abstract

“…(29) The number of previous biopsies did not significantly predict the risk of infection (OR 1.04). (29) The type of antibiotic prophylaxis used was the only significant predictor of infection after biopsy. (29)…”

Section: Discussionmentioning

confidence: 99%

Optimizing safety and accuracy of prostate biopsy

Jones

Radtke²,

Hadaschik³

et al. 2016

Current Opinion in Urology

View full text Add to dashboard Cite

Purpose of review The objective of this article is to examine the safety of prostate biopsy and discuss the emerging role of MRI - ultrasound fusion technology in improving diagnostic accuracy. Recent findings Men undergoing prostate biopsy frequently experience minor complications, including hematospermia, hematuria, and infection. Quinolone-resistant bacteria are a growing concern; thus transperineal access or modification of antibiotic prophylaxis based on local antibiograms is now used to avoid infectious complications. Multiparametric MRI allows visualization of many prostate cancers, and by fusing MRI with realtime ultrasound, a biopsy needle can be directed by a urologist into suspicious regions of interest. Using this new method, detection of clinically significant prostate cancer (csCaP) has increased and the incidence of falsely negative biopsies has decreased. Summary Prostate biopsy is generally a safe procedure, and with attention to local patterns of antibiotic resistance, infectious complications can be minimized. MRI - ultrasound fusion has significantly improved the accuracy of prostate biopsy, allowing tracking and targeting not previously possible.

show abstract

“…The AS protocols were approved to delay radical treatment and spare treatment; however AS can influence quality of life related to health defined as "a physical, mental, and social well-being and not merely the absence of disease" [3]. In fact AS consists in repeating rectal examination, serial PSA evaluations and yearly repeated biopsies, that may be associated with side effects: haematuria, haemospermia, infection, [4][5][6], anxiety and Erectile Dysfunction (ED) [6].…”

Section: Introductionmentioning

confidence: 99%

New Onset of Erectile Dysfunction in a Cohort of Patients Enrolled in Active Surveillance for Low Risk Prostate Cancer: A Preliminary Study to Evaluate Incidence and Prognostic Factors

Quaresima¹,

Polito²

2016

Reprod Syst Sex Disord

View full text Add to dashboard Cite

Objective: Active Surveillance (AS) is a viable alternative to surgery or radiotherapy dedicated to selected patients suffering from low-risk prostate cancer. Aim of the study was to evaluate the onset of Erectile Dysfunction (ED) in patients underwent to AS option and identify potential factors associated to the onset of ED. Methods:From January 2011 to May 2014 were prospectively assessed patients included in AS; we evaluated baseline comorbidity including Diabetes, Hypertension, Body Mass Index (BMI), International Prostate Symptoms Score (IPSS) and International Index of Erectile Function-5 (IIEF-5) score. Were excluded from the assessment patients with baseline ED, defined as an IIEF-5 score < 22 and patient with follow-up less than 24 months. Results:Among the 28 patients underwent to AS aged between 48 and 67 years who meet the selection criteria, 16 (57%) developed new onset of ED with different degrees. At multivariate analysis, no comorbidity were statistically associated to ED even thought a correlation with the onset of E.D. and BMI, Diabetes, Hypertension and age were founded. Conclusions:AS is associated to a high occurrence of ED; among the comorbidities, BMI, Diabetes and Hypertension showed a correlation to a new onset of ED; additional studies are needed to confirm this hypothesis.

show abstract

Complications after prostate biopsies in men on active surveillance and its effects on receiving further biopsies in the Prostate cancer Research International: Active Surveillance (PRIAS) study

Cited by 54 publications

References 20 publications

A Decade of Active Surveillance in the PRIAS Study: An Update and Evaluation of the Criteria Used to Recommend a Switch to Active Treatment

A Decade of Active Surveillance in the PRIAS Study: An Update and Evaluation of the Criteria Used to Recommend a Switch to Active Treatment

Optimizing safety and accuracy of prostate biopsy

New Onset of Erectile Dysfunction in a Cohort of Patients Enrolled in Active Surveillance for Low Risk Prostate Cancer: A Preliminary Study to Evaluate Incidence and Prognostic Factors

Contact Info

Product

Resources

About