Comparison of the efficacy of new laser flow cytometer UF-5000 with UF-1000i in predicting bacteria growth patterns in patients with uncomplicated urinary tract infections

Chen, Y.; Yang, Chun‐Chun; Chang, S-J.; Song, Yang

doi:10.1016/s2666-1683(20)33592-8

Cited by 2 publications

(1 citation statement)

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“…The results showed that UF-5000 could effectively screen the bacterial culture urine samples by selecting the appropriate cut-off value of white blood cell count and bacterial count. There was a signi cant concordance between the positive results of bacterial classi cation and bacterial culture (9)(10)(11)(12)(13). At present, there is little research on the comprehensive analysis and establishment of a perfect screening strategy.…”

Section: Introductionmentioning

confidence: 97%

Sysmex UC-3500 and UF-5000 urine pipeline can quickly and effectively exclude bacterial urinary tract infection

Chen

Zhang

Diao

et al. 2022

Preprint

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ObjectAim to study the role of urine pipeline composed of Sysmex urine dry chemistry analyzer UC-3500 and urine particle analyzer UF-5000 in screening bacterial urinary tract infection (UTI).MethodsWe analyzed 2600 urine specimens from patients with suspected UTI using a urine dry chemistry analyzer (UC-3500) and a fully automated sediment analyzer (UF-5000). After the instruments test, all specimens were sent to our clinical microbiology laboratory with a culture request.ResultsThe consistency of UF-5000 bacterial classification and bacterial culture was fair(kappa = 0.3387). The level of WBC, NIT, was raised with sequential group designs(P<0.001). The cut-off value of BACT was 104.80/µ L for males (AUC,0.956, 95%CI,0.936–0.976) and 705.50/µL for females (AUC,0.940, 95%CI,0.920–0.959). The Youden index, sensitivity, and specificity of BACT were relatively high, which were sufficient for diagnosing infection. All six schemes had good negative predictive value (NPV), and coincidence rate. The NPV of strategy② was 97.54%.ConclusionUF-5000 classification of bacteria can’t be used as a practical reference. 163.25/µL(male), 50.20/µL(female) for WBC and 104.80 /µL(male), 705.50 /µL(female) for BACT were used as cut off values, which could effectively determine whether UTI occurred. The single index BACT parameter is suitable for the rapid and effective exclusion of bacterial UTI.

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Section: Introductionmentioning

confidence: 97%