Comparison of the efficacy of a synthetic dog‐appeasing pheromone with clomipramine for the treatment of separation‐related disorders in dogs

Gaultier, E.; Bonnafous, L.; Bougrat, L.; Lafont, Céline; Pageat, Patrick

doi:10.1136/vr.156.17.533

Cited by 59 publications

(66 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Results of the physiological parameters appear to be consistent with the observations made in various species treated with pheromones belonging to the appeasines range (Gaultier et al, 2005). Indeed, we noticed a stabilization of heart rates, and limitation of the extent of cardiac emotional reaction.…”

Section: Discussionsupporting

confidence: 77%

See 1 more Smart Citation

Effect of a synthetic equine maternal pheromone during a controlled fear-eliciting situation

Falewee¹,

Gaultier²,

Lafont³

et al. 2006

Applied Animal Behaviour Science

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 77%

“…Pheromonotherapy (Pageat, 2001;Pageat and Gaultier, 2003) enables a simplification of treatment for anxiety and phobia related issues in various species (dogs, cats, rabbits, pigs) (Gaultier et al, 2005;Griffith et al, 2000;Mc Glone et al, 1993) but its effectiveness in horses has only been studied in isolated cases.…”

Section: Introductionmentioning

confidence: 99%

Effect of a synthetic equine maternal pheromone during a controlled fear-eliciting situation

Falewee¹,

Gaultier²,

Lafont³

et al. 2006

Applied Animal Behaviour Science

View full text Add to dashboard Cite

“…Previous studies have shown the value of using a synthetic analogue of the dog-appeasing pheromone (DAP) (CEVA Santé Animale) in a variety of fear-inducing circumstances, such as transport (Gaultier and Pageat 2003, Gandia Estellés and Mills 2006), separation from people (Gaultier and others 2005, 2008), firework displays (Sheppard and Mills 2003), attendance at veterinary clinics (Mills and others 2006) and living in a shelter for dogs (Tod and others 2005). In two placebo-controlled studies, in which DAP was used with puppies during an eight-week training programme, Denenberg and others (2005) and Denenberg and Landsberg (2008) observed that puppies without DAP were more distracted and expressed more fear-related signs, such as aggression, avoidance, submissive urination, and fearful postures when facing new circumstances.…”

mentioning

confidence: 99%

Efficacy of dog‐appeasing pheromone in reducing behaviours associated with fear of unfamiliar people and new surroundings in newly adopted puppies

Gaultier¹,

Bonnafous²,

Vienet-Lagué³

et al. 2009

Veterinary Record

Self Cite

View full text Add to dashboard Cite

This study was designed to determine the potential value of dog-appeasing pheromone (DAP) in reducing behaviours associated with fear of unfamiliar people and new surroundings in puppies newly adopted from a pet shop. The study was triple-blinded, randomised and placebo-controlled. It used 66 puppies (32 fitted with a DAP collar and 34 control) and the adoptive owners were contacted by phone three days and 15 days after they had adopted the puppy to question them about its reactions to specific situations eliciting fear. Fifteen days after the treatments significantly fewer of the puppies with the DAP collars showed signs of fear when facing unfamiliar people at home and/or during outings. This difference was irrespective of breed size.

show abstract

“…It can be delivered into the home via a plug-in air diffuser and has been reported to be useful in relieving canine anxiety associated with firework noises (Sheppard and Mills, 2003), travelling (Gandia Estelles and Mills, 2006), being left alone (Gaultier et al, 2005) and within the rescue shelter environment (Tod et al, 2005). In all these situations, tendency to vocalise in particular was reduced.…”

Section: Introductionmentioning

confidence: 99%

A placebo-controlled study to investigate the effect of Dog Appeasing Pheromone and other environmental and management factors on the reports of disturbance and house soiling during the night in recently adopted puppies (Canis familiaris)

Taylor¹,

Mills²

2007

Applied Animal Behaviour Science

View full text Add to dashboard Cite

Disturbance and house soiling during the night are common problems faced by the new puppy dog owner. They may result as consequence of a mismatch between the developmental status of the puppy and its new environment and/or separation distress in a typically social animal. The aim of this study was to examine the effect of Dog Appeasing Pheromone (DAP, Ceva Santé Animale) as well as a range of other management and environmental factors that might affect this process. It has been suggested that DAP may help the puppy settle into the new home by continuing the provision of the maternal appeasing pheromone. In order to test this, a double-blind, placebo-controlled trial of DAP was conducted with 60 pedigree puppies, aged between 6 and 10 weeks, as they entered their new home. A few days prior to the puppy's arrival, volunteer owners were supplied with either a verum or placebo plug-in diffuser designed for the slow release of the pheromone analogue over 4 weeks. Owners reported daily on disturbance and house soiling during the previous night over the following 8 weeks from the puppy's first night in the new home. The effect of the treatment together with the gender of the puppy, its maternal environment, the use of a puppy crate, sleeping with other dogs at night and the experience of the owner were included in a general linear model to explain the total number of nights spent disturbing and house soiling. Sleeping with another dog reduced the puppies' tendency to disturb at night to almost zero. Over 70% of puppies sleeping alone disturbed during the first night. The mean total number of nights of disturbance over the 2 months was between five and six nights, mostly in the first week in the home. A significant effect of DAP treatment was found in the case of the gundog breeds only ( p = 0.003), gundogs receiving placebo cried for a median of nine nights, those receiving verum cried for a median of three nights. No effect of DAP treatment was observed on the total number of nights that the puppy soiled the house ( p > 0.05). However, puppies that were placed in crates during the night ( p = 0.004) or had come from domestic maternal environments ( p = 0.006) had significantly fewer reports of house soiling over the first 2 months in the new home. #

show abstract

Comparison of the efficacy of a synthetic dog‐appeasing pheromone with clomipramine for the treatment of separation‐related disorders in dogs

Cited by 59 publications

References 20 publications

Effect of a synthetic equine maternal pheromone during a controlled fear-eliciting situation

Effect of a synthetic equine maternal pheromone during a controlled fear-eliciting situation

Efficacy of dog‐appeasing pheromone in reducing behaviours associated with fear of unfamiliar people and new surroundings in newly adopted puppies

A placebo-controlled study to investigate the effect of Dog Appeasing Pheromone and other environmental and management factors on the reports of disturbance and house soiling during the night in recently adopted puppies (Canis familiaris)

Contact Info

Product

Resources

About