2015
DOI: 10.1016/j.bjane.2013.12.003
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Abstract: Twenty two of 60 patients included in the study were male and 38 were female. In both groups significant improvements were detected in all of the observed parameters: visual analog scale, Western Ontario McMaster Osteoarthritis Index (pain, physical activity, knee stiffness) and Lequesne index scores and in the evaluations performed in 1st week, 1st month and 3rd month with respect to pre-treatment values. Besides, a better compliance to treatment and gastrointestinal system tolerability in tenoxicam IA group … Show more

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Cited by 5 publications
(11 citation statements)
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“…Of the two studies that did not use Kellgren–Lawrence scores one used an unspeficied, but similar radiologic severity criteria 50 and the other did not use a radiologic severity criteria 49,50 . Of the nine studies using Kellgren–Lawrence scoring, studies most commonly included patients with Kellgren–Lawrence scores of 2 or 3 ( N = 6); however, some studies included patients with Kellgren–Lawrence scores of 0 or 1 ( N = 3) 48,51,52 …”
Section: Resultsmentioning
confidence: 99%
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“…Of the two studies that did not use Kellgren–Lawrence scores one used an unspeficied, but similar radiologic severity criteria 50 and the other did not use a radiologic severity criteria 49,50 . Of the nine studies using Kellgren–Lawrence scoring, studies most commonly included patients with Kellgren–Lawrence scores of 2 or 3 ( N = 6); however, some studies included patients with Kellgren–Lawrence scores of 0 or 1 ( N = 3) 48,51,52 …”
Section: Resultsmentioning
confidence: 99%
“…Most studies did not clearly define primary versus secondary outcomes. Only 3 studies used a statistical correction for multiple comparisons 9,52,53 . Of the three studies that did not use VAS, one study had their own scoring system based only on pain with various degrees of movement 50 .…”
Section: Resultsmentioning
confidence: 99%
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“…The most studied species of the family is tenoxicam (Tenox), IUPA name: 4‐hydroxy‐2‐methyl‐N‐2‐pyridinyl‐2H‐thieno(2,3‐e)‐1,2‐thiazine‐3‐carboxamide 1,1‐dioxide.Tenox is a well‐established non‐steroidal anti‐inflammatory drug, widely used as treatment for various musculoskeletal and joint disorders, rheumatoid arthritis, knee osteoarthritis, acute gout, and symptomatic relief of pain, inflammation and post‐surgical pain. It is characterized by its good efficacy and reduced side effects in comparison to other NSAIDs . It has a five‐membered heteroatom ring that strengthens the clinical activity of the drug, and its neutral molecule exists in the keto–enol form (Figure ).…”
Section: Introductionmentioning
confidence: 99%
“…Diğer yandan tenoksikam, oksikam sınıfından bir NSAİİ olup uzun yarı ömürlü olması özelliğiyle diz ve omuz eklemi içi uygulamaları ağrı yönetiminde sıkça kullanılmaktadır [6]. Yine tenoksikamın yapılan invitro çalışmalarda OA'lı kartilaj dokusunda faydalı olabileceği ve kıkırdaktan ziyade sinovyumda biriktiği, kondroprotektif etkili olduğu, proteoglikanaz ve kollagenaz enzimlerini inhibe ederek kıkırdak yıkımını azalttığı ve böylece dejenerasyonun ilerlemesini azalttığı gösterilmiştir [7][8][9]. Literatürde Ha ve tenoksikam uygulamalarının etkinliğinin değerlendirildiği bir çok klinik ve deneysel çalışma bulunmaktadır [7][8][9][10][11][12][13][14][15][16][17][18].…”
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