Comparison of the complications of traditional 12 cores transrectal prostate biopsy with image fusion guided transperineal prostate biopsy

Huang, Haifeng; Wang, Wei; Lin, Tong; Zhang, Qing; Zhao, Xiaozhi; Lian, Huibo; H, Guo

doi:10.1186/s12894-016-0185-z

Cited by 38 publications

(31 citation statements)

References 18 publications

(20 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Additionally, targeted biopsy may reduce the infection rate as a result of the lower number of cores taken [29]. In a recent study comparing transrectal sysPbx with transperineal targeted biopsy, Huang et al [30] reported a significantly lower infection rate in the transperineal cohort. In the present study, which focused on determining the benefit of fusPbx, sysPbx and comPbx, we therefore combined the standard transrectal with the transperineal approach.…”

Section: Discussionmentioning

confidence: 99%

Prospective comparison of transperineal magnetic resonance imaging/ultrasonography fusion biopsy and transrectal systematic biopsy in biopsy‐naïve patients

et al. 2017

View full text Add to dashboard Cite

ObjectivesTo evaluate the value of multiparametric magnetic resonance imaging (mpMRI) in the detection of significant prostate cancer (PCa) and to compare transperineal MRI/ ultrasonography fusion biopsy (fusPbx) with conventional transrectal systematic biopsy (sysPbx) in biopsy-na€ ıve patients. Patients and MethodsThis multicentre, prospective trial investigated biopsy-na€ ıve patients with suspicion of PCa undergoing transperineal fusPbx in combination with transrectal sysPbx (comPbx). The primary outcome was the detection of significant PCa, defined as Gleason pattern 4 or 5. We analysed the results after a study period of 2 years. ResultsThe study included 214 patients. The median (range) number of targeted and systematic cores was 6 (2-15) and 12 (6-18), respectively. The overall PCa detection rate of comPbx was 52%. FusPbx detected more PCa than sysPbx (47% vs 43%; P = 0.15). The detection rate of significant PCa was 38% for fusPbx and 35% for sysPbx (P = 0.296). The rate of missed significant PCa was 14% in fusPbx and 21% in sysPbx. ComPbx detected significantly more significant PCa than fusPbx and sysPbx alone (44% vs 38% vs 35%; P < 0.005). In patients presenting with Prostate Imaging Reporting and Data System (PI-RADS) 4 and 5 lesions there was a higher detection rate of significant PCa than in patients presenting with PI-RADS ≤3 lesions in comPbx (61% vs 14%; P < 0.005). ConclusionsFor biopsy-na€ ıve men with tumour-suspicious lesions in mpMRI, the combined approach outperformed both fusPbx and sysPbx in the detection of overall PCa and significant PCa. Thus, biopsy-na€ ıve patients may benefit from sysPbx in combination with mpMRI targeted fusPbx.

show abstract

Section: Discussionmentioning

confidence: 99%

Prospective comparison of transperineal magnetic resonance imaging/ultrasonography fusion biopsy and transrectal systematic biopsy in biopsy‐naïve patients

et al. 2017

View full text Add to dashboard Cite

show abstract

“…With regard to complications, with TR prostate biopsy, the incidence rate of infection and rectal bleeding is higher [16] and lesions located in the anterior part of the prostate, particularly in high volume prostates, might be missed. With TP prostate biopsy, on the other hand, the incidence of perineal swelling is higher [16], and, usually for ensuring more patient comfort, it needs to be done in general anesthesia, holding its own risks.…”

Section: Introductionmentioning

confidence: 99%

“…With TP prostate biopsy, on the other hand, the incidence of perineal swelling is higher [16], and, usually for ensuring more patient comfort, it needs to be done in general anesthesia, holding its own risks.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of MRI/Ultrasound Fusion-Guided Prostate Biopsy Using Transrectal and Transperineal Approaches

Tewes

Peters

Tiemeyer

et al. 2017

BioMed Research International

View full text Add to dashboard Cite

Purpose To evaluate transrectal (TR) and transperineal (TP) approaches for MRI/ultrasound (MRI/US) fusion-guided biopsy to detect prostate cancer (PCa). Materials and Methods 154 men underwent multiparametric MRI and MRI/US fusion-guided biopsy between July 2012 and October 2016. 79/154 patients were biopsied with a TR approach and 75/154 with a TP approach. MRI was retrospectively analyzed according to PI-RADS version 2. PI-RADS scores were compared with histopathological results. Descriptive statistics, accuracy, and negative and positive predictive values were calculated. Histopathological results of first, second, and third MRI targeted biopsy cores were compared to evaluate the impact of one verus multiple targeted cores. Results Detection rates of PCa were 39% for TR biopsy and 75% for TP biopsy. Sensitivity/specificity for tumor detection with PI-RADS ≥ 4 were 81/69% for TR biopsy and 86/84% for TP biopsy. In 31% for TR biopsy and 19% for TP biopsy, PCa was found in the second or third MRI targeted biopsy core only. Conclusion MRI/US fusion-guided biopsy may be conducted with the TR as well as the TP approach with high accuracy, giving more flexibility for diagnosis and the option for focal treatment of PCa.

show abstract

“…Since this study was a retrospective analysis, it was subject to data collection restrictions and did not provide information about postoperative complications. However, current studies have shown that the incidence rates of complications did not differ significantly among the 8‐ to 12‐core biopsy methods . Therefore, we believe that if there is evidence supporting statistically significant differences in the PCa and csPCa detection rates, we should use the biopsy method with the higher detection rate.…”

Section: Discussionmentioning

confidence: 78%

“…However, current studies have shown that the incidence rates of complications did not differ significantly among the 8-to 12-core biopsy methods. 20,27 Therefore, we believe that if there is evidence supporting statistically significant differences in the PCa and csPCa detection rates, we should use the biopsy method with the higher detection rate. This work was a retrospective study, and all of the information used was based on historical data from a US workstation.…”

Section: Discussionmentioning

confidence: 99%

How Many Cores Does Systematic Prostate Biopsy Need?: A Large‐Sample Retrospective Analysis

Wang

Sun

et al. 2018

J of Ultrasound Medicine

View full text Add to dashboard Cite

Objectives To explore the best individualized systematic prostate biopsy method. Methods We retrospectively analyzed the clinical data of 1211 patients who underwent 12‐core systematic prostate biopsy guided by transrectal ultrasound from January 2011 to March 2018. Other biopsy core methods (6‐, 8‐, and 10‐core) were estimated from the 12‐core biopsy that was performed. Differences in the detection rates of prostate cancer (PCa) and clinically significant prostate cancer (csPCa) were compared. Results A total of 498 cases of PCa (41.1%) were detected, and 423 cases (34.9%) were csPCa. There was no significant difference between the 12‐ and 10‐core prostate biopsy strategies in the total detection rates of PCa and csPCa (P > .05). In the subgroup of patients with a maximal prostate cross‐sectional area of less than 15 cm2, there was a significant difference between the 12‐core method and the standard 6‐core method (P = .03) but no significant differences between the other methods in the detection rate of PCa (P > .05), but in the detection rate of csPCa, the 12‐core method differed significantly from the other methods (P = .02–.04) except for the 10‐core method (P > .05). In patients with a prostate‐specific antigen concentration of 20 ng/mL or higher, there were no significant differences between the 12‐core method and all of the other methods (P > 0.05). In patients younger than 70 years and 70 years or older, the 12‐core method differed significantly from the other methods (P < .01–.03) except for the 10‐core method (P > .05). Conclusions Ten‐ or 12‐core biopsy showed a higher detection rate than the other schemes. However, for patients with a prostate‐specific antigen concentration of 20 ng/mL or higher, the 6‐core systematic biopsy is preferred.

show abstract

Comparison of the complications of traditional 12 cores transrectal prostate biopsy with image fusion guided transperineal prostate biopsy

Cited by 38 publications

References 18 publications

Prospective comparison of transperineal magnetic resonance imaging/ultrasonography fusion biopsy and transrectal systematic biopsy in biopsy‐naïve patients

Prospective comparison of transperineal magnetic resonance imaging/ultrasonography fusion biopsy and transrectal systematic biopsy in biopsy‐naïve patients

Evaluation of MRI/Ultrasound Fusion-Guided Prostate Biopsy Using Transrectal and Transperineal Approaches

How Many Cores Does Systematic Prostate Biopsy Need?: A Large‐Sample Retrospective Analysis

Contact Info

Product

Resources

About