Abstract:In this study, a mathematical model of bacterial resistance considering the immune system response and antibiotic therapy is examined under random conditions. A random model consisting of random differential equations is obtained by using the existing deterministic model. Similarly, stochastic effect terms are added to the deterministic model to form a stochastic model consisting of stochastic differential equations. The results from the random and stochastic models are also compared with the results of the de… Show more
“…The approximate expected value of 2 is shown in Figure 2. It should be noted that more terms are needed for accurate approximate expectations [ 1 ], [ 2 ]. The first three terms have been given to present the calculation method and to underline the improvements obtained by the modification.…”
Section: Expected Value Of the Two Dimensional Zeeman Modelmentioning
In this paper, the differential transformation method is used to examine the random Zeeman Heartbeat Model. Some of the parameters and the initial conditions of the model are taken as random variables with Beta and Normal distributions, respectively. The approximate analytical solution of the random Zeeman Model is obtained and used to find the expectation and variance of the model components. The results from the random models including Beta and normal distributed random effects are compared and the approximate numerical characteristics are obtained for these cases. The approximate formulas are also modified by using Laplace-Padé Method to increase the convergence interval of the approximations.
“…The approximate expected value of 2 is shown in Figure 2. It should be noted that more terms are needed for accurate approximate expectations [ 1 ], [ 2 ]. The first three terms have been given to present the calculation method and to underline the improvements obtained by the modification.…”
Section: Expected Value Of the Two Dimensional Zeeman Modelmentioning
In this paper, the differential transformation method is used to examine the random Zeeman Heartbeat Model. Some of the parameters and the initial conditions of the model are taken as random variables with Beta and Normal distributions, respectively. The approximate analytical solution of the random Zeeman Model is obtained and used to find the expectation and variance of the model components. The results from the random models including Beta and normal distributed random effects are compared and the approximate numerical characteristics are obtained for these cases. The approximate formulas are also modified by using Laplace-Padé Method to increase the convergence interval of the approximations.
“…model such events is a better modeling approach in contrast to the deterministic case. Several popular methods are used for analyzing stochastic differential equation systems, such as Euler-Maruyama and Milstein methods [1,2], which are the pioneering approximation techniques.…”
In this study, three Ito stochastic differential equations with multiplicative noise are investigated with Wong-Zakai method. The stochastic differential equations are also analyzed by Euler-Maruyama, Milstein and Runge Kutta stochastic approximation methods. The relative errors of these three methods are compared and the performance of Wong-Zakai method is shown alongside numerical results.
“…The parameters in the deterministic System (1) are added random effects to investigate the random characteristics of the model. A random analysis of models using random differential equations with random parameters has been used before for a model of avian-influenza by Merdan and Khaniyev in 2008 and for bacterial resistance by Merdan et al, which was the motivation for the method used in this work [ 18 , 32 ]. The random model is analyzed to investigate the numerical characteristics of the event and thus comment on the random behavior of the model components.…”
The deterministic stability of a model of Hepatitis C which includes a term defining the effect of immune system is studied on both local and global scales. Random effect is added to the model to investigate the random behavior of the model. The numerical characteristics such as the expectation, variance and confidence interval are calculated for random effects with two different distributions from the results of numerical simulations. In addition, the compliance of the random behavior of the model and the deterministic stability results is examined.
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