Comparison of Quorum Sensing Inhibition and Antimicrobial Properties of Some Commercial and Wild Mushrooms Extracted with Supercritical CO2

Abstract

Recently, bioactive properties of mushrooms have been intensively investigated, and their wealth in bioactive compounds particularly of medicinal properties have increased their consumption. In this study, quorum sensing inhibition and anti-microbial properties of some commercial and wild mushroom species were investigated. Agaricus bisporus species were purchased from three different commercial companies. Laccaria bicolor, Bovista plumbea, Lactarius deliciosus and Boletus edulis were collected from Trabzon, Turkey. Compounds extractions were performed using supercritical fluid extraction (CO2) method. Quorum sensing inhibition activity was tested using Chromobacterium violaceum as bacterium-model. Antimicrobial potential of extracts was tested using agar well diffusion method against Staphylococcus aureus, Escherichia coli, Enterococcus faecalis, Pseudomonas aeruginosa, Salmonella Typhimurium, Klebsiella pneumoniae, Proteus mirabilis, Listeria monocytogenes, Candida parapsilosis and Candida albicans. All wild mushroom extracts except for B. plumbea inhibited the violacein production of C. violaceum. L. bicolor, A. bisporus (1), B. plumbea, A. bisporus (2) extracts inhibited the bacterial growth of S. aureus. In addition, L. bicolor extract inhibited K. pneumoniae and L. monocytogenes whereas A. bisporus (2) extract inhibited P. aeruginosa. Among all mushrooms, L. bicolor extract showed remarkable results.