Comparison of Outcomes of Asymptomatic Moderate Aortic Stenosis With Preserved Left Ventricular Ejection Fraction in Patients ≥80 Years Versus 70-79 Years Versus &lt;70 Years

Chew, Nicholas; Kong, Gwyneth; Ngiam, Jinghao Nicholas; Phua, Kailun; Cheong, Clare; Sia, Ching‐Hui; Kuntjoro, Ivandito; Wen, Rong; Loh, Poay-Huan; Lee, Chi‐Hang; Kong, William; Yeo, Tiong‐Cheng; Tan, Huay‐Cheem; Poh, Kian‐Keong

doi:10.1016/j.amjcard.2021.07.015

Cited by 10 publications

(3 citation statements)

References 23 publications

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“…This finding was supported by a study done among HCWs in China (39). The possible reasons are individuals who perceive the COVID-19 disease as severe and serious might choose to be vaccinated (49). Again, it's known that the health belief model (HBM) is a widely used model in vaccination behavior, particularly COVID-19.…”

Section: Discussionmentioning

confidence: 75%

Acceptance of COVID-19 vaccine and associated factors among health care workers at public hospitals in Eastern Ethiopia using the health belief model

Getachew

Lami

Eyeberu

et al. 2022

Front. Public Health

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IntroductionAcceptance of vaccination among Health Care Workers is mandatory to lessen and curve the spread of transmission of COVID-19. Even though the Health Belief Model is one of the most widely used models for understanding vaccination behavior against COVID-19 disease, COVID-19 vaccine acceptance among Health Care Workers in Ethiopia was not adequately explored by using the Health Belief Model domains.PurposeThis study aimed to assess COVID-19 vaccine acceptance and associated factors among Health care workers in eastern, Ethiopia.MethodsInstitutional-based cross-sectional study design was used among 416 health care workers selected by a systematic random sampling method from June 1- 30/2021. The data were collected by face-to-face interviews using semi-structured questionnaires and analyzed using STATA version 14 statistical software. Multivariable binary logistic regression analysis with a 95% confidence interval was carried out to identify factors associated with willingness to COVID-19 vaccine acceptance and a statistical significance was declared at a P-value < 0.05.ResultsThe willingness of health care workers to accept the COVID-19 vaccine was 35.6% making a response rate of 99.7%. Age 30-39 (AOR = 4.16;95% CI: 2.51, 6.88), age ≥ 40 years (AOR = 3.29;95% CI: 1.47, 7.39), good attitude (AOR = 1.97; 95% CI: 1.00, 3.55), perceived susceptibility (AOR = 1.93; 95% CI: 1.12, 3.32), and perceived severity (AOR = 1.78; 95% CI: 1.03, 3.10) were factors significantly associated with Health Care Workers acceptance of COVID-19 vaccine.ConclusionThe willingness to accept the COVID-19 vaccine was low. Factors significantly associated with the willingness to accept the COVID-19 vaccine were age, good attitude, perceived susceptibility, and perceived severity of the disease. The low willingness of Health Care Workers to accept the COVID-19 vaccine was alarming and it needs more emphasis from the government in collaboration with other stakeholders to provide reliable information to avert misconceptions and rumors about the vaccine to improve the vaccine status of Health Care Workers to protect the communities.

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Section: Discussionmentioning

confidence: 75%

Acceptance of COVID-19 vaccine and associated factors among health care workers at public hospitals in Eastern Ethiopia using the health belief model

Getachew

Lami

Eyeberu

et al. 2022

Front. Public Health

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“…A report showed that only 21% of HCWs in Egypt held a positive attitude toward COVID-19 vaccines (25). A survey on the Asia Pacific region showed that the acceptance of COVID-19 vaccines by HCWs in six countries, including China and India, approached nearly 96% (16). Since a compulsory vaccination program can effectively increase the overall vaccination coverage rate (83), we considered the views of HCWs on this measure, and the results showed that approximately 59% of HCWs agreed with it.…”

Section: Discussionmentioning

confidence: 99%

Acceptance of coronavirus disease 2019 (COVID-19) vaccines among healthcare workers: A meta-analysis

Wang

Cheng

et al. 2022

Front. Public Health

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Background: The coronavirus disease (COVID-) pandemic has posed increasing challenges to global health systems. Vaccination against COVIDcan e ectively prevent the public, particularly healthcare workers (HCWs), from being infected by this disease.Objectives: We aim to understand the factors influencing HCWs' acceptance of COVID-vaccines.Methods: We searched PubMed, Embase and Web of Science to collect literature published before May , , about HCWs' acceptance of COVID-vaccines. The Newcastle-Ottawa quality assessment scale was used to assess the risk of bias and the quality of the included studies. We utilized Stata . software for this meta-analysis with a random-e ects model, and odds ratios (ORs) with % confidence intervals (CIs) were reported. This meta-analysis was conducted in alignment with the preferred reporting items for systematic review and meta-analysis (PRISMA) guideline.Results: Our meta-analysis included articles with , HCWs involved. The research showed that the acceptance of vaccines had significantly increased among HCWs compared to non-HCWs (OR = . , % CI: . -. ). A willingness to undergo COVID-vaccination was observed in % ( % CI: . -. ) of HCWs. Among the HCWs involved, doctors showed a generally increased intention to be vaccinated compared with nurses (OR = . , % CI: . -. ). Additionally, males were found to hold more positive attitudes toward vaccination than females (OR = . , % CI: . -. ). When the e ectiveness of COVID-vaccines was improved, the vaccination acceptance of HCWs was greatly increased accordingly (OR = . , % CI: . -. ). The HCWs who were willing to vaccinate against seasonal influenza showed an increased acceptance of COVID-vaccines (OR = . , % CI: . -. ). Our study also showed that HCWs who were willing to be vaccinated against COVIDexperienced a reduced rate of severe acute respiratory syndrome coronavirus (SARS-CoV-) infection (OR = . , % CI: . -. ).

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“…Both European and American guidelines for the management of valvular heart diseases mostly focus on severe aortic stenosis with indications for TAVI or SAVR mainly driven by age and comorbidities. 1,5 Nonetheless, several small recent studies individually showed that mAS (even if asymptomatic) might negatively affect prognosis, [12][13][14][15][16][17][18][19][20][21][22][23][24][25][26] although a precise estimate of the mortality risk associated with mAS is unknown. Some older studies revealed that mAS is relatively benign, but the definition of the disease and the population affected have changed over time.…”

Section: Discussionmentioning

confidence: 99%

Natural history and clinical burden of moderate aortic stenosis: a systematic review and explorative meta-analysis

Morelli

Galasso

Esposito

et al. 2023

Journal of Cardiovascular Medicine

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Aims The mortality risk of patients with moderate aortic stenosis is not well known, but recent studies suggested that it might negatively affect prognosis. We aimed to assess the natural history and clinical burden of moderate aortic stenosis and to investigate the interaction of patients’ baseline characteristics with prognosis. Methods Systematic research was conducted on PubMed. The inclusion criteria were inclusion of patients with moderate aortic stenosis; and report of the survival at 1-year follow-up (minimum). Incidence ratios related to all-cause mortality in patients and controls of each study were estimated and then pooled using a fixed effects model. All patients with mild aortic stenosis or without aortic stenosis were considered controls. Meta-regression analysis was performed to assess the impact of left ventricular ejection fraction and age on the prognosis of patients with moderate aortic stenosis. Results Fifteen studies and 11 596 patients with moderate aortic stenosis were included. All-cause mortality was significantly higher among patients with moderate aortic stenosis than in controls in all timeframes analysed (all P < 0.0001). Left ventricular ejection fraction and sex did not significantly impact on the prognosis of patients with moderate aortic stenosis (P = 0.4584 and P = 0.5792), while increasing age showed a significant interaction with mortality (estimate = 0.0067; 95% confidence interval: 0.0007–0.0127; P = 0.0323). Conclusion Moderate aortic stenosis is associated with reduced survival. Further studies are necessary to confirm the prognostic impact of this valvulopathy and the possible benefit of aortic valve replacement.

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Comparison of Outcomes of Asymptomatic Moderate Aortic Stenosis With Preserved Left Ventricular Ejection Fraction in Patients ≥80 Years Versus 70-79 Years Versus <70 Years

Cited by 10 publications

References 23 publications

Acceptance of COVID-19 vaccine and associated factors among health care workers at public hospitals in Eastern Ethiopia using the health belief model

Acceptance of COVID-19 vaccine and associated factors among health care workers at public hospitals in Eastern Ethiopia using the health belief model

Acceptance of coronavirus disease 2019 (COVID-19) vaccines among healthcare workers: A meta-analysis

Natural history and clinical burden of moderate aortic stenosis: a systematic review and explorative meta-analysis

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