2016
DOI: 10.1055/s-0036-1580603 View full text |Buy / Rent full text
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Abstract: The selection of mitral valve surgery, including mitral valve repair and mitral valve replacement, is still an important dilemma for patients with chronic ischemic mitral regurgitation. We carry out a meta-analysis to evaluate the effectiveness and safety of mitral valve repair versus replacement for ischemic mitral regurgitation. We searched PubMed, Embase, the Cochrane Library, and Web of Science to identify studies from their inception to July 2015. A meta-analysis was performed using RevMan 5.3 software (C… Show more

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“…While mortality did not differ between groups in the CTSN trial, the trial was not powered to detect differences in survival. In contrast, a recent meta-analysis that included this CTSN trial [19] and previous five meta-analyses [20][21][22][23][24] reported lower 30-day mortality associated with MVr compared to MVR.…”
Section: Discussionmentioning
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“…While mortality did not differ between groups in the CTSN trial, the trial was not powered to detect differences in survival. In contrast, a recent meta-analysis that included this CTSN trial [19] and previous five meta-analyses [20][21][22][23][24] reported lower 30-day mortality associated with MVr compared to MVR.…”
Section: Discussionmentioning
“…While mortality did not differ between groups in the CTSN trial, the trial was not powered to detect differences in survival. In contrast, a recent meta‐analysis that included this CTSN trial 19 and the previous five meta‐analyses 20–24 reported lower 30‐day mortality associated with MVr compared to MVR.…”
Section: Discussionmentioning
“…Some authors found lower mortality with MV repair versus MV replacement (66), although others did not observe significant differences (67,68). Several studies describe an increase in the recurrence of IMR with MV repair (19,66,(68)(69)(70), although this does not usually translate into a worsening of functional status, quality of life or the appearance of major adverse events (19,68). The American Association for Thoracic Surgery Guidelines are the only ones, so far, that offer us guidance based on the presence or absence of different predictors of IMR recurrence (basal aneurysm/dyskinesia, significant venous traction, ventricular dilation) (59).…”
Section: Replacement Versus Repairmentioning