Comparison of Left Atrial Volume Parameters in Detecting Left Ventricular Diastolic Dysfunction Versus Tissue Doppler Recordings

Hsiao, Shih Hung; Lin, Kun‐Der; Chiou, Kuan Rau

doi:10.1016/j.amjcard.2011.10.040

Cited by 35 publications

(44 citation statements)

References 27 publications

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“…Recent work by the authors showed that the LA expansion index, which accurately reflects instantaneous LV filling pressure (logarithmic correlation) in many disease entities, is useful for predicting AF after coronary artery bypass graft surgery. [16][17][18][19][20] Because the LA expansion index mirrors LV filling pressure, we hypothesized that the LA expansion index predicts long-term events not only in patients with heart disease, but also in relatively low-risk subjects such as consecutive patients visiting cardiovascular clinics for dyspnea.…”

mentioning

confidence: 99%

Left Atrial Expansion Index Predicts Atrial Fibrillation in Dyspnea

Hsiao

Chiou

2013

Circ J

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confidence: 99%

Left Atrial Expansion Index Predicts Atrial Fibrillation in Dyspnea

Hsiao

Chiou

2013

Circ J

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“…This study demonstrated that maximal and minimal LA volumes and LAEF were associated linearly with LV filling pressures. It was further shown that LA distensibility and LA ejection fraction had logarithmic association with filling pressures and were more accurate in predicting LVEDP [15 mmHg than E/e 0 ratio [29]. Nonetheless, it has been recently shown that RFP may also be related to duration of myocardial ischemia [23], which was not confirmed in our study.…”

Section: Discussionmentioning

confidence: 81%

“…However, the large LA may not able to further dilate faced with increased LVEDP in MI [25][26][27][28] which is why we postulated that mild increase in LAVI (normal ± 1SD or 28 ml/m 2 ) can Our data also suggest that initial rise of LVEDP may cause LA dilatation before restrictive filling pattern develops, indicating that LA volume may be a more sensitive indicator of duration of ischemia than restrictive filling pattern. The potential of LA volume to reflect the increase in LVEDP during AMI has been investigated in the study including more than 600 patients, who underwent simultaneous cardiac catheterization with LVEDP [29]. This study demonstrated that maximal and minimal LA volumes and LAEF were associated linearly with LV filling pressures.…”

Section: Discussionmentioning

confidence: 89%

Relationship of ischemic times and left atrial volume and function in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention

Ilić

Stanković

Vidaković

et al. 2015

Int J Cardiovasc Imaging

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Little is known about the impact of duration of ischemia on left atrial (LA) volumes and function during acute phase of myocardial infarction. We investigated the relationship of ischemic times, echocardiographic indices of diastolic function and LA volumes in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI). A total of 433 consecutive STEMI patients underwent echocardiographic examination within 48 h of primary PCI, including the measurement of LA volumes and the ratio of mitral peak velocity of early filling to early diastolic mitral annular velocity (E/e'). Time intervals from onset of chest pain to hospital admission and reperfusion were collected and magnitude of Troponin I release was used to assess infarct size. Patients with LA volume index (LAVI) ≥28 ml/m(2) had longer total ischemic time (410 ± 347 vs. 303 ± 314 min, p = 0.007) and higher E/e' ratio (15 ± 5 vs. 10 ± 3, p < 0.001) than those with LAVI <28 ml/m(2), while the indices of LA function were similar between the study groups (p > 0.05, for all). Significant correlation was found between E/e' and LA volumes at all stages of LA filling and contraction (r = 0.363-0.434; p < 0.001, for all) while total ischemic time along with E/e' and restrictive filling pattern remained independent predictor of LA enlargement. Increased LA volume is associated with longer ischemic times and may be a sensitive marker of increased left ventricular filling pressures in STEMI patients treated with primary PCI.

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“…Abnormal diastolic functioning results in elevated LV filling pressures that are transmitted back to the left atrium [5]. The thin-walled atrium is seriously affected by increased load, and the elevated LA pressures result in an increase in LA wall tension and enlargement of the LA [6]. Mild LA enlargement is common in HCM.…”

Section: Discussionmentioning

confidence: 99%

“…The thin-walled left atrium is sensitive to volume and pressure changes. Sustained elevated pressure on the left atrium leads to its remodeling, which is closely associated with the occurrence of AF [6,7,8]. …”

Section: Introductionmentioning

confidence: 99%

Assessment of Atrial Conduction Abnormalities in Patients with Hypertrophic Cardiomyopathy Before and One Year after Alcohol Septal Ablation

Shi¹,

Yuan²,

Zhang

et al. 2012

Cardiology

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Objectives: Intra- and interatrial electromechanical delay (AEMD) can be used to evaluate the development of atrial fibrillation (AF). Percutaneous transluminal septal myocardial ablation (PTSMA) is an alternative therapy for patients with hypertrophic obstructive cardiomyopathy (HOCM) that results in sustained improvements in atrial structure and function. We investigated the effects of PTSMA on the intra- and inter-AEMD of HOCM patients using tissue Doppler imaging. Methods: Conventional echocardiographic and AEMD parameters were obtained in 25 healthy controls and 31 HOCM patients before and 1 year after septal ablation procedures. Results: Compared with the healthy controls, the left atrial volumes indexed by body surface area (LAVI) and the intra- and inter-AEMD were significantly higher in the HOCM patients. At 1 year after PTSMA, the LAVI was decreased (37.2 ± 11.4 to 27.0 ± 8.5 ml/m², p < 0.001). The intra- and inter-AEMD were also significantly decreased (22.7 ± 9.2 to 16.6 ± 7.7 ms, p < 0.001 and 37.0 ± 8.4 to 26.6 ± 8.0 ms, p < 0.001, respectively). These changes correlated well with the reductions in LAVI (r = 0.83, p < 0.001; r = 0.66, p < 0.001). Conclusions: Both the intra- and inter-AEMD were significantly prolonged in the HOCM patients. PTSMA can improve the prolonged and inhomogeneous propagation of sinus impulses in atria.

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Comparison of Left Atrial Volume Parameters in Detecting Left Ventricular Diastolic Dysfunction Versus Tissue Doppler Recordings

Cited by 35 publications

References 27 publications

Left Atrial Expansion Index Predicts Atrial Fibrillation in Dyspnea

Left Atrial Expansion Index Predicts Atrial Fibrillation in Dyspnea

Relationship of ischemic times and left atrial volume and function in patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention

Assessment of Atrial Conduction Abnormalities in Patients with Hypertrophic Cardiomyopathy Before and One Year after Alcohol Septal Ablation

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