Comparison of Innovative and Traditional Cardiometabolic Indices in Estimating Atherosclerotic Cardiovascular Disease Risk in Adults

Abstract

This study aimed to investigate the performance of innovative and traditional cardiometabolic indices, including body mass index (BMI), waist circumference (WC), Chinese visceral adiposity index (CVAI), visceral adiposity index, lipid accumulation product, a body shape index (ABSI), body roundness index, conicity index (CI), triglyceride-glucose (TyG) index, TyG-BMI, and TyG-WC, in estimating atherosclerotic cardiovascular disease (ASCVD) risk in 3143 Taiwanese adults aged 20–79 years. Elevated 10-year ASCVD risk was defined as ≥7.5% using the Pooled Cohort Equations. The performance of different indices in estimating elevated ASCVD risk was assessed by receiver operating characteristic (ROC) curves. In multivariate-adjusted logistic regression analyses, all cardiometabolic indices (p-value < 0.001) were significantly associated with elevated ASCVD risk in both genders, except for ABSI and CI in women. In particular, CVAI had the largest area under the curve (AUC) in men (0.721) and women (0.883) in the ROC analyses. BMI had the lowest AUC in men (0.617), while ABSI had the lowest AUC in women (0.613). The optimal cut-off value for CVAI was 83.7 in men and 70.8 in women. CVAI performed best among various cardiometabolic indices in estimating elevated ASCVD risk. CVAI may be a reliable index for identifying people at increased risk of ASCVD.

Chinese Visceral Adiposity Index Is Associated With Incident Renal Damage in Patients With Hypertension and Abnormal Glucose Metabolism: A Longitudinal Study

“…In a recent cross-sectional study, CVAI showed the strongest association with cardiovascular disease among the commonly used abdominal obesity indices (30). Similarly, several other studies have demonstrated that CVAI is related to cardiovascular risk or its risk factors, such as carotid atherosclerosis (31)(32)(33). Our study extends this field by demonstrating an association between CVAI and incident renal damage.…”

Association Between Chinese Visceral Adiposity Index and Incident Type 2 Diabetes Mellitus in Japanese Adults

“…The study found that CVAI was more effective than various cardiometabolic indices, including BMI, WC, VAI, LAP, ABSI, triglyceride-glucose (TyG) index, TyG-BMI, and TyG-WC. 33 Thus, CVAI is a better predictor of the state of visceral fat than conventional obesity indicators. Therefore, this study suggests that CVAI is a valuable predictive biomarker for new-onset T2DM.…”

Association of Visceral Obesity-Related Indices With Coronary Collateralization in Patients With Chronic Total Occlusion

“…BAI is a marker of adipose function and distribution, and LAP is associated with insulin resistance, reflecting central fat accumulation ( 29 , 30 ). Additionally, mounting evidence supports that these visceral obesity-related indices better identify individuals at elevated risk for metabolic diseases such as T2DM and CVD ( 31 ). For instance, LAP is a better predictor of 10-year cardiovascular events than BMI, and WC and LAP are simple and accurate predictors for metabolic syndrome in undiagnosed adults ( 29 , 32 ).…”