2005
DOI: 10.1111/j.1439-0507.2005.01128.x
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Comparison of in vitro activities of antifungal drugs and ethanolic extract of propolis against Trichophyton rubrum and T. mentagrophytes by using a microdilution assay

Abstract: The in vitro activities of propolis against 29 strains of dermatophytes were compared with those of terbinafine, itraconazole, ketoconazole, and fluconazole. Minimal inhibitory concentrations (MICs) were determined according to a National Committee for Clinical Laboratory Standards broth microdilution method. Among the systemic antifungals tested, terbinafine was the most potent. Propolis showed important antifungal activity and it merits further investigation as a potentially useful agent for the treatment of… Show more

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Cited by 62 publications
(48 citation statements)
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“…These results are consistent with those of Ota et al [22] and Koc et al [23]. Antifungal activity correlated only partially with flavonoid content in extracts, e.g.…”
Section: Discussionsupporting
confidence: 83%
See 1 more Smart Citation
“…These results are consistent with those of Ota et al [22] and Koc et al [23]. Antifungal activity correlated only partially with flavonoid content in extracts, e.g.…”
Section: Discussionsupporting
confidence: 83%
“…As far as the constituents that are probably responsible for the antifungal effects are concerned, they are comparable with propolis samples originating from other countries reported in the literature [20][21][22][23][24][25][26][27][28][29][30][31][32]. Future research of propolis is needed, particularly in the field of isolation and detailed description of its biologically active compounds.…”
Section: Discussionmentioning
confidence: 62%
“…Selection of agar dilution MIC endpoints presents a similar source of variability that must be controlled, but that is not unique to the test of antifungal agents. Koç et al advised that the NCCLS M27-A broth microdilution method was superior for the antifungal activity of propolis (34).…”
Section: Discussionmentioning
confidence: 99%
“…Ethanolic extract of Turkish propolis (PEE) collected from various areas show multi-properties activity as antibacterial (Keskin et al, 2001;Ozcan et al, 2004), antifungal (Koc et al, 2005), antioxidant (Kolankaya et al, 2002;Orhan et al, 1999) and anticarcinogenic (Ozkul et al, 2005). The chemicals compounds in propolis and biological activities depend on different factors such as the geographical regions, collection time and plant source (Bankova, 2005;Hegazi et al, 2014).…”
Section: Introductionmentioning
confidence: 99%