Comparison of Fluid Absorption between Transurethral Enucleation and Transurethral Resection for Benign Prostate Hyperplasia

Abstract

Introduction: Although transurethral resection of prostate (TURP) remains the reference standard for benign prostate hyperplasia(BPH), the concern about complications promotes researchers to develop alternative surgical methods with fewer complications. In this study, we compared the safety and efficacy between the transurethral plasma kinetic enucleation of prostate (TUPKEP) and transurethral plasma kinetic resection of prostate (TUPKRP), mainly including absorption of irrigation fluid, the operation time, the weight of prostate tissue removed and severe complications. Methods: Sixty BPH patients were randomly and evenly assigned to the TUPKEP or TUPKRP group. The irrigation fluid used in both groups was 1% ethanol-containing saline solution. The ethanol concentrations in the subjects' end expiration were measured during operation. The volume of irrigation fluid absorbed was calculated accordingly. Results: No significant difference was found in operation time between two groups, whereas the weight of prostate tissue resection was significantly higher in the TUPKEP than that in the TUPKRP group. Conclusion: The study provides evidence for the safety, feasibility and effectiveness of both bipolar transurethral techniques. Further, compared to the TUPKRP group, the TUPKEP group has more efficient for resection of prostatic hyperplasia tissue, even though in terms of fluid absorption, no difference has been found in both groups. Ethanol monitoring is simple, safe and effective, which is beneficial for enhancing safety procedures.

Thulium Laser Enucleation Versus Plasmakinetic Enucleation of the Prostate: A Randomized Trial of a Single Center

“…However, TURP is still associated with significant morbidity, particularly in patients with larger prostates, including bleeding, capsular perforation, and transurethral resection syndrome (TURS). 1 Thus, the quest for the ultimate and best transurethral therapy in urology continues, and many novel endoscopic technologies, such as laser technique and plasmakinetic technique, were used in the surgical treatment of BPH. 2 Plasmakinetic enucleation of the prostate (PKEP) was introduced to enucleate the prostate adenoma with the electrode loop and resectoscope tip without supernumerary equipment.…”

Plasmakinetic Vapor Enucleation of the Prostate with Button Electrode versus Plasmakinetic Resection of the Prostate for Benign Prostatic Enlargement >90 ml: Perioperative and 3-Month Follow-Up Results of a Prospective, Randomized Clinical Trial

“…This point is of great interest for our future study. The PVEP operation time was longer than some previous studies [11,12], because the tissue morcellator was not used in our study, which could increase the treatment costs and the complication of bladder injury.…”

Changes in mitotic reorientation and Wnt/AR signaling in rat prostate epithelial cells exposed to subchronic testosterone

“…Ran is a member of RAS family and has been shown to be involved in the androgen signaling pathway in addition to the regulation of DNA transcription (22). Although numerous studies have investigated the association between Ran and prostate cancer (23), more recent studies have investigated Ran in the context of benign proliferation of prostate cells (24,25).…”