Comparison of Effect of IV Esmolol and I.V. Metoprolol For Attenuation of Pressor Response to Laryngoscopy And Intubation During Elective General Surgical Procedures Under General Anaesthesia

Shende, Sunita Y.; Gorgile, Rupali N.; Naik, Sanyogita Vijay; Marathe, Radhika M

doi:10.9790/0853-1601010106

Cited by 2 publications

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“…While Panti et al 9 reported that intravenous lidocaine reduces cough resulting from these procedures, very few studies evaluated the efficacy of esmolol to prevent these events. Shende et al 19 did not find superiority in intubation conditions (mandibular relaxation, coughing, patient movements, and vocal cord movements) in patients that received esmolol and metoprolol. In our study, patients who received esmolol had a lower occurrence of coughing or movement, however, there was no statistical difference between the groups.…”

Section: Discussionmentioning

confidence: 94%

Effects of lidocaine and esmolol on hemodynamic response to tracheal intubation: a randomized clinical trial

Mendonça¹,

Silva²,

Nilton³

et al. 2022

Brazilian Journal of Anesthesiology (English Edition)

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Section: Discussionmentioning

confidence: 94%

Effects of lidocaine and esmolol on hemodynamic response to tracheal intubation: a randomized clinical trial

Mendonça¹,

Silva²,

Nilton³

et al. 2022

Brazilian Journal of Anesthesiology (English Edition)

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“…Shende et al, 6 (2017) conducted a randomized controlled trial to compare the effects of bolus doses of metoprolol and esmolol heart rate, systolic blood pressure, and rate pressure product during laryngoscopy and intubation. Sixty patients of ASA I and II randomly received placebo or study group 1mg/kg of esmolol or 80gµg/kg of metoprolol in 20ml normal saline.…”

Section: Discussionmentioning

confidence: 99%

Attenuation of cardiovascular responses to laryngoscopy and intubation –A comparative study between IV esmolol hydrochloride and lignocaine hydrochloride

Gowthami²,

et al. 2022

Asian J Med Sci

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Background: Laryngoscopy and tracheal intubation are frequently associated with sympathetic stress response. Lignocaine and esmolol are useful to decrease the sympathetic response to laryngoscopy and intubation. Aims and Objectives: The aim of the study was to study the effectiveness of lignocaine and esmolol administered intravenously before laryngoscopy and intubation in attenuating the sympathetic response. Materials and Methods: The prospective, randomized, and controlled study was conducted in Maharajah’s Institute of Medical Sciences Hospital for a period of 18 months from January 2016 to June 2017. A clinical comparative study of attenuation of sympathetic response to laryngoscopy and intubation was done in 90 patients posted for elective surgeries. The sample size estimation is calculated based on findings from the previous study done by Singh et al., (2013).Group I was control group. In this group, no drug was administered. Group II was lignocaine group. Here, patients received 1.5mg/kg lignocaine i.v. bolus. Group III was esmolol group. All patients in this group received 2mg/kg i.v. bolus. Statistical Analysis: Descriptive data presented as Mean±SD and in percentage. Pair-wise comparison between the groups was done by “Z” test. For all tests,“Z” value of >1.96 was considered significant and “P’ <0.05” was considered significant. Results: Esmolol at a bolus dose of 2mg/kg i.v. administered 3 min before laryngoscopy and intubation is more efficient than lignocaine given at a dose of 1.5mg/kg. Conclusions: Esmolol at bolus dose of 2mg/kg i.v. administered can be recommended to attenuate sympathetic responses due to laryngoscopy and intubation.

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Comparison of Effect of IV Esmolol and I.V. Metoprolol For Attenuation of Pressor Response to Laryngoscopy And Intubation During Elective General Surgical Procedures Under General Anaesthesia

Cited by 2 publications

References 0 publications

Effects of lidocaine and esmolol on hemodynamic response to tracheal intubation: a randomized clinical trial

Effects of lidocaine and esmolol on hemodynamic response to tracheal intubation: a randomized clinical trial

Attenuation of cardiovascular responses to laryngoscopy and intubation –A comparative study between IV esmolol hydrochloride and lignocaine hydrochloride

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