Comparison of Different Cardiac MRI Sequences at 1.5 T/3.0 T with Respect to Signal-to-Noise and Contrast-to-Noise Ratios - Initial Experience

Gutberlet, M.; Spors, Birgit; Gutberlet, Matthias; Freyhardt, Patrick; Schwinge, Kerstin; Plotkin, Michail; Amthauer, Holger; Noeske, Ralph; Felix, Ramon A.

doi:10.1055/s-2004-813220

Cited by 32 publications

(53 citation statements)

References 7 publications

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“…Cardiac imaging at 3.0 T has demonstrated the potential for significant improvement in signal-to-noise ratios (SNR) and image quality [24,25], but may be associated with greater B 1 and B 0 field inhomogeneities, longer T1 relaxation and power deposition limitations [26]. Multiecho imaging of the heart therefore poses a number of challenges at high field strength.…”

Section: Discussionmentioning

confidence: 99%

Cardiac T2* and lipid measurement at 3.0 T-initial experience

et al. 2007

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This study was designed to assess whether breath-hold cardiac multiecho imaging at 3.0 T is achievable without significant image artefacts and if fat/water phase interference modulates the exponential T2* signal decay. Twelve healthy volunteers (mean age 39) were imaged on a Philips Intera 3.0 T MRI scanner. Multiecho imaging was performed with a breath-hold spoiled gradient echo sequence with a seven echo readout (echo times 1.15-8.05 ms, repetition time 11 ms) using a black-blood prepulse and volume shimming. T2* values were calculated with both mono- and biexpoential fits from the mean signal intensity of the interventricular septum. The global mean T2* was 27.3 ms +/- 6.4. The mean signal-to-noise ratio (SNR) of the septum was 22.8 +/- 9.9, and the contrast-to-noise ratio (CNR) of the septum to the left ventricular cavity 20.3 +/- 9.4. A better fit was obtained with a biexponential model and the mean fat fraction derived was 3.7%. Cardiac functional parameters were in the normal range and showed no correlation with T2*. Cardiac T2* estimation with gradient multiecho imaging at 3.0 T can be achieved with minimal artefact and modelling the signal decay with a biexponential function allows estimation of myocardial lipid content as well as T2* decay.

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Section: Discussionmentioning

confidence: 99%

Cardiac T2* and lipid measurement at 3.0 T-initial experience

et al. 2007

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“…Although we did not perform a direct comparison between 1.5 Tesla and 3.0 Tesla, other studies have shown improvement in SNR at 3.0 Tesla (Gutberlet et al, 2006;Gutberlet et al, 2004;Lotz et al, 2005;Wittlinger et al, 2005). This increase in SNR from 1.5 Tesla to 3.0 Tesla can be bartered to improve either spatial resolution or temporal resolution as desired for a given application.…”

Section: In Vivo Coronary Artery Studymentioning

confidence: 93%

“…Improvements in spatial resolution and signal-to-noise ratio (SNR) for cardiac imaging applications can be achieved by using higher field strength 3.0 Tesla scanners (Gutberlet et al, 2006;Gutberlet et al, 2004). Validation studies of 3.0 Tesla PC-MRI in larger diameter vessels have recently been performed showing good precision and accuracy at high flow rates (Lotz et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

Coronary artery flow measurement using navigator echo gated phase contrast magnetic resonance velocity mapping at 3.0 T

Johnson

Sharma

Oshinski

2008

Journal of Biomechanics

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A validation study and early results for noninvasive, in vivo measurement of coronary artery blood flow using phase contrast magnetic resonance imaging (PC-MRI) at 3.0 Tesla is presented. Accuracy of coronary artery blood flow measurements by phase contrast MRI is limited by heart and respiratory motion as well as the small size of the coronary arteries. In this study, a navigator-echo gated, cine phase velocity mapping technique is described to obtain time-resolved velocity and flow waveforms of small diameter vessels at 3.0 Tesla. Phantom experiments using steady, laminar flow are presented to validate the technique and show flow rates measured by 3.0 Tesla phase contrast MRI to be accurate within 15% of true flow rates. Subsequently, in vivo scans on healthy volunteers yield velocity measurements for blood flow in the right, left anterior descending, and left circumflex arteries. Measurements of average, cross-sectional velocity were obtainable in 224/243 (92%) of the cardiac phases. Time-averaged, cross-sectional velocity of the blood flow was 6.8±4.3 cm/s in the LAD, 8.0 ±3.8 cm/s in the LCX, and 6.0±1.6 cm/s in the RCA.

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“…Among the cardiac applications of MR imaging, signal-to-noise (SNR) limited methods such as myocardial perfusion MR (perfusion MR) are most likely to benefit from higher field strength (1)(2)(3)(4)(5)(6)(7)(8)(9). Initial studies have shown improvements in SNR, contrast enhancement and diagnostic accuracy for perfusion MR at 3.0 Tesla compared with 1.5 Tesla (1,2,5).…”

Section: Introductionmentioning

confidence: 99%

k-Space and Time Sensitivity Encoding–accelerated Myocardial Perfusion MR Imaging at 3.0 T: Comparison with 1.5 T

Plein¹,

Schwitter²,

Suerder³

et al. 2008

Radiology

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Purpose-To determine the feasibility and diagnostic accuracy of high spatial resolution myocardial perfusion MR at 3.0 Tesla using k-space and time domain undersampling with sensitivity encoding (k-t SENSE).Materials and Methods-The study was reviewed and approved by the local ethic review board. k-t SENSE perfusion MR was performed at 1.5 Tesla and 3.0 Tesla (saturation recovery gradient echo pulse sequence, repetition time/echo time 3.0ms/1.0ms, flip angle 15°, 5x k-t SENSE acceleration, spatial resolution 1.3×1.3×10mm 3 ). Fourteen volunteers were studied at rest and 37 patients during adenosine stress. In volunteers, comparison was also made with standardresolution (2.5×2.5×10mm 3 ) 2x SENSE perfusion MR at 3.0 Tesla. Image quality, artifact scores, signal-to-noise ratios (SNR) and contrast-enhancement ratios (CER) were derived. In patients, diagnostic accuracy of visual analysis to detect >50% diameter stenosis on quantitative coronary angiography was determined by receiver-operator-characteristics (ROC).Results-In volunteers, image quality and artifact scores were similar for 3.0 Tesla and 1.5 Tesla, while SNR was higher (11.6 vs. 5.6) and CER lower (1.1 vs. 1.5, p=0.012) at 3.0 Tesla. Compared with standard-resolution perfusion MR, image quality was higher for k-t SENSE (3.6 vs. 3.1, p=0.04), endocardial dark rim artifacts were reduced (artifact thickness 1.6mm vs. 2.4mm, p<0.001) and CER similar. In patients, area under the ROC curve for detection of coronary stenosis was 0.89 and 0.80, p=0.21 for 3.0 Tesla and 1.5 Tesla, respectively. Address for correspondence: Dr. S. Plein, Academic Unit of Cardiovascular Medicine, University of Leeds, G-floor Jubilee Wing, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, United Kingdom, Tel +44 113 3925404, Fax +44 113 3925405, Email: s.plein@leeds.ac.uk. Advances in knowledge 1. k-space and time domain undersampling with sensitivity encoding (k-t SENSE) can be used to accelerate myocardial perfusion MR imaging at 3.0 Tesla. 2.Compared with 1.5 Tesla, k-t SENSE accelerated perfusion MR imaging at 3.0 Tesla improves SNR and yields similar diagnostic accuracy to detect significant coronary artery stenosis.3. Using the acceleration provided by k-t SENSE to improve spatial resolution yields high image quality and reduces image artifacts compared with perfusion MR at lower resolution. Implications for patient care1. The combination of k-t SENSE acceleration with acquisition at high field strength offers a promising tool for improved detection of coronary artery stenosis by perfusion MR imaging. Conclusions-k-t SENSE accelerated high-resolution perfusion MR at 3.0 Tesla is feasible with similar artifacts and diagnostic accuracy as at 1.5 Tesla. Compared with standard-resolution perfusion MR, image quality is improved and artifacts are reduced. Europe PMC Funders Group

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Comparison of Different Cardiac MRI Sequences at 1.5 T/3.0 T with Respect to Signal-to-Noise and Contrast-to-Noise Ratios - Initial Experience

Cited by 32 publications

References 7 publications

Cardiac T2* and lipid measurement at 3.0 T-initial experience

Cardiac T2* and lipid measurement at 3.0 T-initial experience

Coronary artery flow measurement using navigator echo gated phase contrast magnetic resonance velocity mapping at 3.0 T

k-Space and Time Sensitivity Encoding–accelerated Myocardial Perfusion MR Imaging at 3.0 T: Comparison with 1.5 T

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