Comparison of Deaths from COVID-19 and Seasonal Influenza in the USA

Jeganathan, Niranjan; Grewal, Sahib; Sathananthan, Matheni

doi:10.1007/s00408-021-00468-0

Cited by 6 publications

(5 citation statements)

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“…We did not think comparing the SARS-CoV-2 inpatient population to those traditionally admitted to the acute rehabilitation facilities with neurological deficits, traumatic brain injury or spinal cord injury would be a reasonable comparison. A recent study comparing the death rate of influenza and SARS-CoV-2 populations found that the decedents of SARS-CoV-2 were more likely to be male, between the age of 65 and 84 years, and were also more likely to have a higher incidence of a history of diabetes, hypertension, and obesity [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

Predictors of discharge disposition and mortality following hospitalization with SARS-CoV-2 infection

et al. 2023

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Importance The SARS-CoV-2 pandemic has overwhelmed hospital capacity, prioritizing the need to understand factors associated with type of discharge disposition. Objective Characterization of disposition associated factors following SARS-CoV-2. Design Retrospective study of SARS-CoV-2 positive patients from March 7th, 2020, to May 4th, 2022, requiring hospitalization. Setting Midwest academic health-system. Participants Patients above the age 18 years admitted with PCR + SARS-CoV-2. Intervention None. Main outcomes Discharge to home versus PAC (inpatient rehabilitation facility (IRF), skilled-nursing facility (SNF), long-term acute care (LTACH)), or died/hospice while hospitalized (DH). Results We identified 62,279 SARS-CoV-2 PCR+ patients; 6,248 required hospitalizations, of whom 4611(73.8%) were discharged home, 985 (15.8%) to PAC and 652 (10.4%) died in hospital (DH). Patients discharged to PAC had a higher median age (75.7 years, IQR: 65.6–85.1) compared to those discharged home (57.0 years, IQR: 38.2–69.9), and had longer mean length of stay (LOS) 14.7 days, SD: 14.0) compared to discharge home (5.8 days, SD: 5.9). Older age (RRR:1.04, 95% CI:1.041–1.055), and higher Elixhauser comorbidity index [EI] (RRR:1.19, 95% CI:1.168–1.218) were associated with higher rate of discharge to PAC versus home. Older age (RRR:1.069, 95% CI:1.060–1.077) and higher EI (RRR:1.09, 95% CI:1.071–1.126) were associated with more frequent DH versus home. Blacks, Asians, and Hispanics were less likely to be discharged to PAC (RRR, 0.64 CI 0.47–0.88), (RRR 0.48 CI 0.34–0.67) and (RRR 0.586 CI 0.352–0.975). Having alpha variant was associated with less frequent PAC discharge versus home (RRR 0.589 CI 0.444–780). The relative risks for DH were lower with a higher platelet count 0.998 (CI 0.99–0.99) and albumin levels 0.342 (CI 0.26–0.45), and higher with increased CRP (RRR 1.006 CI 1.004–1.007) and D-Dimer (RRR 1.070 CI 1.039–1.101). Increased albumin had lower risk to PAC discharge (RRR 0.630 CI 0.497–0.798. An increase in D-Dimer (RRR1.033 CI 1.002–1.064) and CRP (RRR1.002 CI1.001–1.004) was associated with higher risk of PAC discharge. A breakthrough (BT) infection was associated with lower likelihood of DH and PAC. Conclusion Older age, higher EI, CRP and D-Dimer are associated with PAC and DH discharges following hospitalization with COVID-19 infection. BT infection reduces the likelihood of being discharged to PAC and DH.

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Section: Discussionmentioning

confidence: 99%

Predictors of discharge disposition and mortality following hospitalization with SARS-CoV-2 infection

et al. 2023

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“…Considerable attention has been given to outcomes of patients hospitalised with COVID-19 6 8–12. However, limited attention has been given to outpatient care of patients with COVID-19, including managing increased volume of secure messages and clinic visits and developing guidelines for triage to the acute care setting.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of an outreach programme for patients with COVID-19 in an integrated healthcare delivery system: a retrospective cohort study

Myers,

Lawson,

Escobar

et al. 2024

BMJ Open

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ObjectivesIn the first year of the COVID-19 pandemic, health systems implemented programmes to manage outpatients with COVID-19. The goal was to expedite patients’ referral to acute care and prevent overcrowding of medical centres. We sought to evaluate the impact of such a programme, the COVID-19 Home Care Team (CHCT) programme.DesignRetrospective cohort.SettingKaiser Permanente Northern California.ParticipantsAdult members before COVID-19 vaccine availability (1 February 2020–31 January 2021) with positive SARS-CoV-2 tests.InterventionVirtual programme to track and treat patients with ‘CHCT programme’.OutcomesThe outcomes were (1) COVID-19-related emergency department visit, (2) COVID-19-related hospitalisation and (3) inpatient mortality or 30-day hospice referral.MeasuresWe estimated the average effect comparing patients who were and were not treated by CHCT. We estimated propensity scores using an ensemble super learner (random forest, XGBoost, generalised additive model and multivariate adaptive regression splines) and augmented inverse probability weighting.ResultsThere were 98 585 patients with COVID-19. The majority were followed by CHCT (n=80 067, 81.2%). Patients followed by CHCT were older (mean age 43.9 vs 41.6 years, p<0.001) and more comorbid with COmorbidity Point Score, V.2, score ≥65 (1.7% vs 1.1%, p<0.001). Unadjusted analyses showed more COVID-19-related emergency department visits (9.5% vs 8.5%, p<0.001) and hospitalisations (3.9% vs 3.2%, p<0.001) in patients followed by CHCT but lower inpatient death or 30-day hospice referral (0.3% vs 0.5%, p<0.001). After weighting, there were higher rates of COVID-19-related emergency department visits (estimated intervention effect −0.8%, 95% CI −1.4% to −0.3%) and hospitalisation (−0.5%, 95% CI −0.9% to −0.1%) but lower inpatient mortality or 30-day hospice referral (−0.5%, 95% CI −0.7% to −0.3%) in patients followed by CHCT.ConclusionsDespite CHCT following older patients with higher comorbidity burden, there appeared to be a protective effect. Patients followed by CHCT were more likely to present to acute care and less likely to die inpatient.

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“…The annual number of deaths from influenza-related respiratory diseases is estimated to be approximately 650,000 (7). Compared with other seasonal flu pathogens, the transmission rate and mortality rate of COVID-19 were found to be higher (8). Therefore, more stringent measures such as mask-distance and hand hygiene (MDH), isolation, and quarantine practices have been adopted to prevent the spread of the virus compared with other pandemics.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Mask-Distance-Hygiene Measures on Non-Covid-19 Viral Upper Respiratory Tract Diseases

Akgündüz,

Uçan,

Özdemir

2024

esmj

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ÖZET Amaç: Bu çalışmada pandemi döneminde uygulanan maske, mesafe ve el hijyeni uygulamalarının COVID-19 dışı üst solunum yolu viral enfeksiyonlarına etkisinin araştırılması amaçlanmıştır. Yöntemler: Araştırma kesitsel anket araştırması olarak dizayn edildi. Göğüs hastalıkları kliniğine başvuran hasta ve hasta yakınlarına pandemi öncesi ve pandemi döneminde ilk bir yıl içerisinde COVID-19 dışı mevsimsel viral üst solunum yolu enfeksiyonu semptom ve bulgularının sorgulandığı bir anket uygulandı. Bulgular: 322 katılımcının yaş ortalaması 44.5±15.4 idi. Katılımcıların 177’si (%55) kadındı. 133 katılımcı pandemi öncesi ve sonrası Üst Solunum Yolu Enfeksiyonu(ÜSYE) geçirmemişti. Pandemi öncesi dönemde, pandemi dönemine göre ÜSYE nedeniyle hastaneye başvuranların oranı 1.28 kat daha fazlaydı. Katılımcıların %34.8’i COVID-19 öncesi ÜSYE geçirmemişti. Bu olguların %19.6’sı pandemi döneminde ÜSYE geçirmişti. Pandemi öncesi ÜSYE geçirenlerin oranı pandemi sonrası ÜSYE geçirenlere göre daha yüksekti ve bu istatistiksel olarak anlamlıydı. (p:0.001). Sonuç: Maske kullanımı solunumsal viral patojenlerin yayılmasında, hastalığın önlenmesinde etkili olmuştur. Özellikle bu patojenlerin görüldüğü mevsimlerde pandemi sonrasında da maskemesafe- el hijyeni kurallarının toplumda uygulanmasının sürekliliğinin sağlanması hastalıkların önlenmesinde basit ve etkili yöntemlerdir. Anahtar Sözcükler: COVID-19, viral üst solunum yolu enfeksiyon, maske, mesafe, el hijyen

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Comparison of Deaths from COVID-19 and Seasonal Influenza in the USA

Cited by 6 publications

References 1 publication

Predictors of discharge disposition and mortality following hospitalization with SARS-CoV-2 infection

Predictors of discharge disposition and mortality following hospitalization with SARS-CoV-2 infection

Evaluation of an outreach programme for patients with COVID-19 in an integrated healthcare delivery system: a retrospective cohort study

The Effect of Mask-Distance-Hygiene Measures on Non-Covid-19 Viral Upper Respiratory Tract Diseases

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