volume 93, issue 0, P3-P-354 2020
DOI: 10.1254/jpssuppl.93.0_3-p-354
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Abstract: The structure of piceatannol (PIC) is similar to that of a polyphenol resveratrol (RSV), an activator of an NAD +dependent protein deacetylase SIRT1. However, whether the PIC exhibit cytoprotective effect through the SIRT1 activation remains unclear. Here we compared to the cytoprotective effect through SIRT1 activation of PIC and RSV. [Results and Methods] We used the C2C12 myoblasts in this experiment. Treatment with antimycin A, an inhibitor of complex III that induces reactive oxygen species (ROS), fluore…

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