Comparison of aspiration with sclerotherapy and laparoscopic deroofing for the treatment of symptomatic simple renal cysts: a systematic review and meta-analysis

Abstract

There are currently several strategies for the treatment of symptomatic simple renal cysts, such as aspiration with sclerosants and laparoscopic deroofing. However, no clear indication exists for choosing between them. Here, we carried out a systematic review and a meta-analysis of studies, which compared symptomatic and radiological success between aspiration with sclerotherapy and laparoscopic deroofing. Results were reported as relative risk (RR) and 95% confidence interval (95% CI) using laparoscopic deroofing as control group. The symptomatic and radiological successes were evaluated by 6 and 3 studies, respectively. Notably, aspiration with sclerotherapy was associated with higher risk of failure than laparoscopic deroofing (RR = 2.82; 95% CI = 1.84–4.31 for symptomatic failure; RR = 8.31; 95% CI = 4.22–16.38 for radiological failure). On the other hand, however, aspiration with sclerotherapy was associated with less frequent complications, shorter treatment duration and post-treatment hospital stay, and lower costs. Thus, our work underlines benefits and drawbacks of each intervention, raising the need for further studies to design guidelines for the management of simple renal cysts.

Sclerotherapy of a Symptomatic Renal Cyst

“…It was reported that complications such as bleeding and infection were more common in the laparoscopic treatment group, and the operation time and hospital stay were prolonged as well. 12 Recently, pediatric literature also supports using sclerosing agent injection as the first option for symptomatic renal cysts before considering surgical intervention. 13 Additionally, Koenig et al presented a newborn with a giant renal cyst treated successfully with sclerosing agent treatment, which was treated successfully.…”

Successful management of a mixed epithelial and stromal renal tumor masquerading as lower pole renal cyst: A laparoscopic deroofing approach

“…Imaging studies are crucial for accurate diagnosis and management planning [2] . While laparoscopic deroofing is a well-established approach for symptomatic renal cysts, the finding of a MEST within such a cyst is exceedingly rare [3,4] .…”