Comparison of antibacterial efficacy of cinnamon extract, neem extract as irrigant and sodium hypochlorite against Enterococcus fecalis: An in vitro study

Panchal, Veerale; Gurunathan, Deepa; Muralidharan, N. P.

doi:10.4103/ijdr.ijdr_177_18

Cited by 14 publications

(12 citation statements)

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“…The effect of cinnamon EO as a root canal irrigant is weaker than 3% NaOCl but could lead to 80–85% intracanal bacterial reduction [ 87 ]. A 20% ethanolic extract of C. zeylanicum was found to be even more effective against E. faecalis ATCC 29212 compared to 3% NaOCl [ 88 ]. The significant antimicrobial effect of C. cassia EO was proved against C. albicans and E. faecalis (MIC was 0.56 mg/mL).…”

Section: Antimicrobial Effect Of Cinnamon Eo and Cinnamon Extractsmentioning

confidence: 99%

Effects of Cinnamon (Cinnamomum spp.) in Dentistry: A Review

Yanakiev

2020

Molecules

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Dental medicine is one of the fields of medicine where the most common pathologies are of bacterial and fungal origins. This review is mainly focused on the antimicrobial effects of cinnamon essential oil (EO), cinnamon extracts, and pure compounds against different oral pathogens and the oral biofilm and the possible effects on soft mouth tissue. Basic information is provided about cinnamon, as is a review of its antimicrobial properties against the most common microorganisms causing dental caries, endodontic and periodontal lesions, and candidiasis. Cinnamon EO, cinnamon extracts, and pure compounds show significant antimicrobial activities against oral pathogens and could be beneficial in caries and periodontal disease prevention, endodontics, and candidiasis treatment.

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Section: Antimicrobial Effect Of Cinnamon Eo and Cinnamon Extractsmentioning

confidence: 99%

Effects of Cinnamon (Cinnamomum spp.) in Dentistry: A Review

Yanakiev

2020

Molecules

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“…Cinnamon extract irrigant shows better reduction in E. faecalis as compared to three percent of sodium hypochlorite and neem extract irrigant 47 . The sugar sweetened cinnamon chewing gum may benefit halitosis by reducing volatile sulphur compounds producing anaerobes within the mouth.…”

Section: Cinnamon Zeylanicummentioning

confidence: 88%

Herbal Care in Dentistry- A Review of Emerging Trends

Shilpa

Mahalakshmi

2022

IJCD

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Herbs are staging a comeback and herbal ‘renaissance’ is happening all over the globe. The herbal products, today, symbolize safety, in contrast to the synthetics that are regarded as unsafe to humans and the environment. An herb, botanically speaking, is any plant that lacks the woody tissue which is characteristic of shrubs or trees. More specifically, herbs are plants which are used medicinally or for their flavor or scent. Herbs with medicinal properties are a useful and an effective source of treatment for various disease processes. Herbal extracts have been successfully used in dentistry as tooth cleaning and antimicrobial plaque agents. The use of herbal medicines continues to expand rapidly across the world. Many people take herbal medicines or herbal products now for their health care in different national healthcare settings. Herbal extracts have been used in dentistry for reducing inflammation, as antimicrobial plaque agents, for preventing release of histamine and as antiseptics, antioxidants, antimicrobials, antifungals, antibacterials, antivirals and analgesics. They also aid in healing and are effective in controlling microbial plaque in gingivitis and periodontitis, thereby improving immunity.

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“…In fact, some studies suggest that neem has greater antibacterial activity than Commiphora myrrha (myrrh), Acacia tree (e.g., catechu), Cinnamomum verum (cinnamon), Salvadora persica (miswak), Syzygium aromaticum (clove), Zingiber officinale (ginger), Allium sativum (garlic) and Curcuma longa (tumeric) extracts against some species of bacteria and cultured dental caries ( Kanth et al, 2016 ; Jagannathan et al, 2020 ; Arora et al, 2021 ). This being said, it is important to note that certain bacterial species (e.g., S. mutans and E. faecalis ) appear to be more susceptible to extracts from other plants in some studies ( Jain et al, 2015 ; Dedhia et al, 2018 ; Kalita et al, 2019 ; Panchal et al, 2020 ). While this does not diminish the antimicrobial potential of A. indica , it does underline the importance of thoroughly taking advantage of the wide variety of antimicrobial plants and compounds that are at the disposal of modern medicine.…”

Section: Antibacterial Evidencementioning

confidence: 98%

“…and Shigella spp. that have been tested, which includes more than a dozen multidrug-resistant isolates from patients suffering from typhoid fever complications, are susceptible to seed, bark, and leaf extracts of neem from either ethanol, methanol, or acetone extraction; in some cases, the activity of neem extract was also found to be greater than that of gentamycin, erythromycin, and other plants used in traditional medicine ( Mahfuzul Hoque et al, 2007 ; Susmitha et al, 2013 ; Tesso et al, 2015 ; Melese et al, 2016 ; Al Akeel et al, 2017 ; Panchal et al, 2020 ; Essuman et al, 2021 ). Similarly, dried leaf, seed, and bark neem extracts in any of the three previously mentioned solvents have significant antibacterial activity against E. coli , with the methanolic extract of neem seeds demonstrating the greatest level of activity ( Susmitha et al, 2013 ; Sharma and Nupur, 2014 ; Melese et al, 2016 ).…”

Section: Antibacterial Evidencementioning

confidence: 99%

The Antimicrobial Potential of the Neem Tree Azadirachta indica

Wylie

Merrell

2022

Front. Pharmacol.

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Azadirachta indica (A. Juss), also known as the neem tree, has been used for millennia as a traditional remedy for a multitude of human ailments. Also recognized around the world as a broad-spectrum pesticide and fertilizer, neem has applications in agriculture and beyond. Currently, the extensive antimicrobial activities of A. indica are being explored through research in the fields of dentistry, food safety, bacteriology, mycology, virology, and parasitology. Herein, some of the most recent studies that demonstrate the potential of neem as a previously untapped source of novel therapeutics are summarized as they relate to the aforementioned research topics. Additionally, the capacity of neem extracts and compounds to act against drug-resistant and biofilm-forming organisms, both of which represent large groups of pathogens for which there are limited treatment options, are highlighted. Updated information on the phytochemistry and safety of neem-derived products are discussed as well. Although there is a growing body of exciting evidence that supports the use of A. indica as an antimicrobial, additional studies are clearly needed to determine the specific mechanisms of action, clinical efficacy, and in vivo safety of neem as a treatment for human pathogens of interest. Moreover, the various ongoing studies and the diverse properties of neem discussed herein may serve as a guide for the discovery of new antimicrobials that may exist in other herbal panaceas across the globe.

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Comparison of antibacterial efficacy of cinnamon extract, neem extract as irrigant and sodium hypochlorite against Enterococcus fecalis: An in vitro study

Cited by 14 publications

References 0 publications

Effects of Cinnamon (Cinnamomum spp.) in Dentistry: A Review

Effects of Cinnamon (Cinnamomum spp.) in Dentistry: A Review

Herbal Care in Dentistry- A Review of Emerging Trends

The Antimicrobial Potential of the Neem Tree Azadirachta indica

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