Comparison between cine magnetic resonance velocity mapping and first-pass radionuclide angiocardiography for quantitating intracardiac shunts

Mohiaddin, Raad H.; Underwood, Richard; Romeira, Leopoldo; Anagnostopoulos, Constantinos; Karwatowski, Stefan P.; Laney, R.; Somerville, Jane

doi:10.1016/s0002-9149(99)80600-6

Cited by 34 publications

(12 citation statements)

References 21 publications

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“…This was done initially by tedious manual or semiautomated tracking of endocardial contours on a stack of end-diastolic and end-systolic GRE images of both ventricles. Later on, many have successfully applied Q-PCA of the ascending aorta and pulmonary artery, to quantify ASD, VSD or PDA shunt lesions [4,18,59,76,94,109]. This technique allows simple and reliable measurement of the pulmonary-to-systemic flow ratio, a crucial parameter in surgical decision-making.…”

Section: A 8b 8cmentioning

confidence: 99%

Congenital Heart Disease. Evaluation of Anatomy and Function by MRI

Rebergen¹,

Roos

2000

Herz

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With the increasing number of patients surviving after therapeutic intervention for congenital heart disease (CHD), accurate and frequent follow-up of their morphologic and functional cardiovascular status is required, preferably with a noninvasive imaging technique. Echocardiography, either transthoracic or transesophageal, has been the first choice for this purpose, and will probably keep that status, at least in a large segment of the CHD spectrum. Magnetic resonance imaging (MRI) is an established method for high-resolution visualization of cardiovascular morphology. In the past decade, newer MRI techniques have been developed that allow functional evaluation of CHD patients. Particularly the introduction of breath-hold imaging, contrast-enhanced MRA and user-friendly computer software for image analysis may move functional MRI of CHD from the science laboratory to clinical use. It is already evident that MRI is superior to echocardiography in certain areas of limited echocardiographic access, such as the pulmonary artery branches and the aortic arch in adult patients. But MRI has also a unique potential for accurate volumetric analysis of ventricular function and cardiovascular blood flow, without any geometric assumptions. If supported by increased cooperation between cardiologists and radiologists, MRI will grow into a useful noninvasive imaging tool that, together with echocardiography, will obviate the need for invasive catheter studies for diagnostic purposes.

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Section: A 8b 8cmentioning

confidence: 99%

Congenital Heart Disease. Evaluation of Anatomy and Function by MRI

Rebergen¹,

Roos

2000

Herz

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“…Shunt volume can be derived by comparison of either flow volumes through the ascending aorta and the pulmonary trunk (Fig. 6C) (33,36) or right and left ventricular stroke volumes (37).…”

Section: Total Repair Of Tetralogy Of Fallotmentioning

confidence: 99%

Postoperative evaluation of congenital heart disease by magnetic resonance imaging

Roest

Helbing

Wall

et al. 1999

J. Magn. Reson. Imaging

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“…Spin-echo MR imaging can often demonstrate the defect itself, and also right atrial and/or right ventricular enlargement and anomalous pulmonary venous return [6,7]. From gradient-echo MR cine loops, shunt flow can often be identified, and with MR velocity mapping, pulmonary and aortic volumetric blood flow can be measured to calculate the Qp : Qs ratio [9,10,14,15]. MR velocity mapping can also be used to visualize shunt flow directly [11].…”

Section: Mr Imaging: Additional Valuementioning

confidence: 99%

“…The clinical usefulness and accuracy of MR velocity mapping for flow measurements in the great arteries has been demonstrated previously [11][12][13]. This technique has already been used for the quantification of left to right shunts [9,10,14,15], but not often in young children. MR flow quantification studies can be obtained and analyzed within several minutes and they can complete the evaluation of ASD with MR imaging when added to the conventional spin-echo series.…”

Section: Introductionmentioning

confidence: 95%

Quantification of pulmonary and systemic blood flow by magnetic resonance velocity mapping in the assessment of atrial-level shunts

et al. 1996

Int J Cardiac Imag

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The objective of this study was to asses the feasibility and accuracy of magnetic resonance (MR) velocity mapping to calculate pulmonary-to-systemic flow ratio (Qp:Qs) in patients with a suspected or diagnosed atrial-level shunt. During a one-year period, all patients referred to our department for further evaluation of an atrial-level shunt underwent the same imaging protocol. Multiphase-multisection gradient-echo MR image sets of the heart were acquired to measure left and right ventricular stroke volumes for validation. Ascending aorta and main pulmonary artery volume flow were measured with MR velocity mapping. Qp:Qs ratios were calculated from both stroke volume data and flow data. Twelve patients, including 6 children, were studied. Six patients had an established diagnosis of atrial septal defect, and the other 6 patients were suspected to have an atrial-level shunt. Measurements of left and right ventricular stroke corresponded closely with those of aortic (r = 0.98) and pulmonary flow (r = 0.99) respectively, and Qp:Qs flow ratios agreed with stroke volume ratios (r = 0.92). In 5 patients with a suspected shunt, the diagnosis could be rejected. Shunts were demonstrated in the other 7 patients. M(r) velocity mapping offers an accurate method to measure aortic and pulmonary artery volume flow that can be useful in the evaluation of atrial-level shunts, in order to establish a definite diagnosis and/or to quantify the Qp:Qs ratio.

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Comparison between cine magnetic resonance velocity mapping and first-pass radionuclide angiocardiography for quantitating intracardiac shunts

Cited by 34 publications

References 21 publications

Congenital Heart Disease. Evaluation of Anatomy and Function by MRI

Congenital Heart Disease. Evaluation of Anatomy and Function by MRI

Postoperative evaluation of congenital heart disease by magnetic resonance imaging

Quantification of pulmonary and systemic blood flow by magnetic resonance velocity mapping in the assessment of atrial-level shunts

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