Compared to Individuals with Mild to Moderate Obstructive Sleep Apnea (OSA), Individuals with Severe OSA Had Higher BMI and Respiratory-Disturbance Scores

Abstract

Objective: Individuals with obstructive sleep apnea (OSA) are at increased risk to suffer from further somatic and sleep-related complaints. To assess OSA, demographic, anthropometric, and subjective/objective sleep parameters are taken into consideration, but often separately. Here, we entered demographic, anthropometric, subjective, and objective sleep- and breathing-related dimensions in one model. Methods: We reviewed the demographic, anthropometric, subjective and objective sleep- and breathing-related data, and polysomnographic records of 251 individuals with diagnosed OSA. OSA was considered as a continuous and as categorical variable (mild, moderate, and severe OSA). A series of correlational computations, X2-tests, F-tests, and a multiple regression model were performed to investigate which demographic, anthropometric, and subjective and objective sleep dimensions were associated with and predicted dimensions of OSA. Results: Higher apnea/hypopnea index (AHI) scores were associated with higher BMI, higher daytime sleepiness, a higher respiratory disturbance index, and higher snoring. Compared to individuals with mild to moderate OSA, individuals with severe OSA had a higher BMI, a higher respiratory disturbance index (RDI) and a higher snoring index, while subjective sleep quality and daytime sleepiness did not differ. Results from the multiple regression analysis showed that an objectively shorter sleep duration, more N2 sleep, and a higher RDI predicted AHI scores. Conclusion: The pattern of results suggests that blending demographic, anthropometric, and subjective/objective sleep- and breathing-related data enabled more effective discrimination of individuals at higher risk for OSA. The results are of practical and clinical importance: demographic, anthropometric, and breathing-related issues derived from self-rating scales provide a quick and reliable identification of individuals at risk of OSA; objective assessments provide further certainty and reliability.

Subjective HRQoL in Patients with Sleep Apnea Syndrome Who Underwent PAP Therapy in a Rehabilitation Setting: A Longitudinal Study

“…Secondly, regarding the comparison between baseline and 1-year follow-up, sleep breathing patterns had normalized after PAP treatment (41.8 ± 20.6 vs. 2.7 ± 2.8, p = 0.001), and we observed a significant reduction in subclinical ESS scores (5.9 ± 3.9 vs. 2.4 ± 2.6, p = 0.001). These data are consistent with the existing literature on the efficacy of the PAP treatment for reducing clinical and sleepiness symptoms, even if patients in this study were not sleepy [28][29][30][31]. In addition, there was a significant reduction of anxious symptoms (6.8 ± 3.6 vs. 5.4 ± 3.8, p = 0.001) and a significant improvement in HRQoL (0.6 ± 0.4 vs. 0.7 ± 0.5, p = 0.032; 70.4 ± 19.0 vs. 79.2 ± 20.3, p = 0.001).…”

Effect of Velopharyngeal Insufficiency on Long-Term Patient-Reported Sleep-Related Impairment in Patients With Cleft Palate

“…Sleep-related impairment was also positively correlated with BMI ≥ 25, similar to the general population. 38,39 When controlling for BMI ≥ 25, a history of VPI, VPI surgery, and sphincter pharyngoplasty were all found to be independently predictive of worse sleep-related impairment in their respective regression models. Of note, patients treated with sphincter pharyngoplasty were assessed on average 12.1 ± 5.2 years after surgery.…”

Effects of the Combination of Continuous Nursing Care and Breathing Exercises on Respiratory Function, Self‐Efficacy, and Sleep Disorders in Patients with Lung Cancer Discharged from Hospital

“…At the same time, sleep disorders can lead to depressed mood in patients, reduce their treatment compliance, reduce the quality of generation and self-cognitive efficacy of patients, and seriously threaten the prognosis of patients. After sleep improvement intervention for patients with lung cancer, it is found [12] that high-quality sleep can significantly improve the physical function and role cognition of patients with lung cancer and increase their response to treatment. Compared with general surgery, lung tissue resection had certain particularities, but there were few reports on the intervention of insomnia disorder in patients with lung cancer after surgery.…”