Compared to an active control condition, in persons with multiple sclerosis two different types of exercise training improved sleep and depression, but not fatigue, paresthesia, and intolerance of uncertainty

Bahmani, Dena Sadeghi; Razazian, Nazanin; Farnia, Vahid; Alikhani, Mostafa; Tatari, Faezeh; Brand, Serge

doi:10.1016/j.msard.2019.07.032

Cited by 42 publications

(44 citation statements)

References 78 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…If this is the case, it is unlikely that dysfunctional personality traits would have been modified by physical activity alone over a 12 weeks period. In a related vein, an intervention program for individuals with Multiple Sclerosis involving regular physical activity produced changes in state variables such as depression and sleep quality, but not trait dimensions such as mental toughness or intolerance of uncertainty [40]. To put it in another way, it would be unwise to overstate the impact of regular physical activity on a broad range of psychological functioning.…”

Section: Discussionmentioning

confidence: 99%

Influence of Regular Physical Activity on Mitochondrial Activity and Symptoms of Burnout—An Interventional Pilot Study

Brand

Ebner

Mikoteit

et al. 2020

JCM

Self Cite

View full text Add to dashboard Cite

Background: Occupational burnout is both a serious public and individual health concern. Psychopharmacological and psychological interventions are often employed, while interventions involving physical activity have been less frequently studied. The aims of the present study were (1) to investigate the effects of physical activity on mitochondrial activity levels and symptoms of burnout, (2) to compare the mitochondrial activity levels and symptoms of burnout of individuals suffering burnout with those of healthy controls (HCs), and (3) to explore the associations between mitochondrial activity and burnout symptoms. Methods: Twelve males with burnout (mean age: M = 45.8 years) took part in the study. At baseline and after 12 weeks of an intervention involving physical activity, participants completed questionnaires covering symptoms of burnout and depression. In parallel, blood samples were taken to measure changes in mitochondrial functional outcomes, such as ATP levels, oxygen consumption and complex I. For comparison, baseline values of healthy controls (HCs; depression and burnout questionnaires; blood samples) were assessed. Results: Over time, symptoms of burnout (emotional exhaustion and depersonalization) and depression significantly decreased in participants with burnout (large effect sizes) but remained significantly higher than those of HCs (medium to large effect sizes). Personal accomplishment increased over time (medium effect size) but was still lower than for HCs (large effect size). At baseline and compared to HCs, individuals with burnout had significantly lower ATP levels of mitochondrial functional outcomes. Over time, mitochondrial activity levels increased among individuals with burnout. High baseline mitochondrial activity was significantly correlated with lower depression and burnout scores both at baseline and at the end of the study. Conclusions: In individuals with burnout, regular physical activity had positive effects on mitochondrial activity and on symptoms of burnout and depression. However, when compared to healthy controls, full remission was not achieved.

show abstract

Section: Discussionmentioning

confidence: 99%

Influence of Regular Physical Activity on Mitochondrial Activity and Symptoms of Burnout—An Interventional Pilot Study

Brand

Ebner

Mikoteit

et al. 2020

JCM

Self Cite

View full text Add to dashboard Cite

show abstract

“…The positive effects of exercise, CBT, or educational interventions in the improvement of sleep disorders in patients with MS has been reported in the previous studies. 10,12,14 It is reported that exercise is associated with changes in endocrine system functioning, as well as reducing depression and anxiety levels that lead to an improvement in quality of sleep. 13 Additionally, the effectiveness of CBT has been attributed to changes in thoughts and behaviors related to sleep which may maintain insomnia.…”

Section: Discussionmentioning

confidence: 99%

“…13 Additionally, the effectiveness of CBT has been attributed to changes in thoughts and behaviors related to sleep which may maintain insomnia. 12,14 As previously stated, the intervention utilized in the present study was based on the PEOP model 32 and focuses on three levels: person, environment, and occupation. In the sleep-targeted program, which is occupation-based, all of these aspects were considered and incorporated into the program.…”

Section: Discussionmentioning

confidence: 99%

“…The intervention used in the current study was compromised of a combination of common interventions used for patients with sleep problems, including patients with MS and those receiving occupational therapy interventions. The common intervention included the interventions which effectiveness have been demonstrated in previous studies in patients with MS such as sleep hygiene education 13 (including an explanation of caffeine intake reduction, excessive night-time eating, and smoking cessation), physical activity 14 (including moderate levels of aerobic exercises during the week lasting 10 to 30 minutes, depending on patient endurance, such as walking, running, and cycling four hours before falling asleep), CBT 12 (including the exploration of dysfunctional thinking patterns surrounding sleep and teaching Jacobson relaxation techniques). Occupational therapy interventions were focused on the occupational balance based on the Person-Environment-Occupation Performance (PEOP) model.…”

Section: Interventionsmentioning

confidence: 99%

“…11,12 Physical activity and aerobic exercise have also received support and studies demonstrate a positive relationship with sleep parameters in patients with MS. 13 However, these interventions produce different effects in the outcome measures of fatigue and depression. 14 Additionally, educational interventions such as improving sleep hygiene behaviors have been recognized as effective methods to improve sleep quality. 15 It is likely that disagreement and controversy exist when determining the most effective method of sleep interventions in MS as a result of the complex nature of this disease and its consequences, including tone disturbance, pain, cognitive disorder, and disability.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

<p>The Effectiveness of Occupational Therapy-Based Sleep Interventions on Quality of Life and Fatigue in Patients with Multiple Sclerosis: A Pilot Randomized Clinical Trial Study</p>

Akbarfahimi

Nabavi

Kor

et al. 2020

NDT

View full text Add to dashboard Cite

Purpose: Sleep difficulties are common in patients with multiple sclerosis (MS), which may increase feelings of fatigue, negatively interfere with daily activities, and consequently reduce their quality of life. Studies examining the effects of sleep-targeted interventions in MS are currently limited in the literature. Therefore, we aim to assess the effects of occupational therapy interventions on sleep quality, fatigue, and quality of life in patients with MS. Patients and Methods: In a single-blind, randomized, controlled trial, which occurred between April 2018 and March 2019 in Tehran, Iran, 20 eligible patients with MS were assessed using the Pittsburgh Sleep Quality Index (PSQI), Fatigue Impact Scale (FIS), Fatigue Severity Scale (FSS), and Short-Form Health Survey (SF-36). Patients were allocated randomly into the two following groups: patients receiving care-as-usual for MS (CAU) and patients receiving care-as-usual plus intervention (CAU + intervention). Both intervention groups underwent 2-3 sessions per week lasting 30-45 minutes for 8 weeks and received follow-up assessments. Data were analyzed using independent sample t-tests and Mann-Whitney U tests using SPSS (16 ver.) statistical software. Results: In the intervention group, sleep quality improved significantly across all items (p<0.001, effect size = 0.60) except for sleep efficiency and the use of sleep medications. FSS and FIS in the sleep intervention group were significantly reduced (p<0.001, effect size = 0.76 and p<0.001, effect size = 0.82, respectively). The quality of life in the intervention group improved significantly (p<0.004, effect size = 0.51-0.76) with the exception of the social functioning subgroup. Conclusion: Although this is the result of a pilot study and more patients should be added, this intervention program demonstrates improvement in sleep quality and quality of life while decreasing fatigue in patients with MS. Adjunction of this program, if results are similar with more patients, to routine occupational therapy (OT) interventions can help improve the rehabilitation program of MS patients.

show abstract

Quality of reporting health behaviors for multiple sclerosis (QuoRH‐MS): A scoping review to inform intervention planning and improve consistency of reporting

Probst,

Kinnane

2024

Brain and Behavior

View full text Add to dashboard Cite

BackgroundMultiple sclerosis (MS) is a neurological condition that necessitates a multidisciplinary approach to aid those living with MS in managing their disease. Health behavior, or lifestyle modification, is an emerging approach to MS self‐management. MS researchers utilize measurement tools to ensure that interventions are best suited to the outcomes, thereby potentially influencing practice. The aim of this study was to investigate which tools are being used for health behavior management studies in people living with MS and develop an aid for tool selection.MethodsA scoping review guided by the PRISMA‐Sc checklist and the JBI manual for evidence synthesis was employed with a systematic search strategy executed across four scientific databases: Medline, PubMed, CINAHL, and Cochrane Libraries. The types of assessment tools used were extracted from the included studies. Each tool was categorized into the health behavior intervention discipline (nutrition, exercise, and psychology) and then subcategorized by the tool's purpose. The frequency of use was determined for each tool. Reporting of validation of the assessment tools were collated to inform a tool selection checklist.ResultsThe review identified a total of 248 tools (12 nutrition, 55 exercise, and 119 psychology unique reports) from 166 studies. Seventy‐seven multidimensional tools were identified including measures of quality of life, fatigue, and functional scales. Only 88 studies (53%) referred to the validity of the tools. The most commonly reported tools were the dietary habits questionnaire (n = 4, nutrition), 6‐minute walk test (n = 17, exercise), Symbol Digits and Modalities Test, and Hospital Anxiety and Depression Scale (n = 15 each, psychology) with the Expanded Disability Status Scale reported 43 times.ConclusionEvidence from interventions may inform practice for health professionals. This review provides insights into the range of tools reported across health behavior intervention studies for MS and offers a guide toward more consistent reporting of study methods.

show abstract

Compared to an active control condition, in persons with multiple sclerosis two different types of exercise training improved sleep and depression, but not fatigue, paresthesia, and intolerance of uncertainty

Cited by 42 publications

References 78 publications

Influence of Regular Physical Activity on Mitochondrial Activity and Symptoms of Burnout—An Interventional Pilot Study

Influence of Regular Physical Activity on Mitochondrial Activity and Symptoms of Burnout—An Interventional Pilot Study

<p>The Effectiveness of Occupational Therapy-Based Sleep Interventions on Quality of Life and Fatigue in Patients with Multiple Sclerosis: A Pilot Randomized Clinical Trial Study</p>

Quality of reporting health behaviors for multiple sclerosis (QuoRH‐MS): A scoping review to inform intervention planning and improve consistency of reporting

Contact Info

Product

Resources

About