Comparative study of two diagnostic methods of demodicosis in patients with acne and rosacea

Kravchenko, Anzhela

doi:10.19100/jdvi.v2i3.62

Cited by 1 publication

(31 citation statements)

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“…47 Treatment monitoring was the focus of six studies (43%), 28,33,[46][47][48][49] while the remaining 8 (57%) characterized acne lesions, unaffected skin in acne patients or both. 27,29,30,32,44,45,50,51 Acne severity was not reported in four articles (28.57%). 45,47,50,51 Most articles (i.e.…”

Section: R E Su Ltsmentioning

confidence: 99%

“…27,29,30,32,44,45,50,51 Acne severity was not reported in four articles (28.57%). 45,47,50,51 Most articles (i.e. 7%-50%) considered patients with mild-moderate acne, [28][29][30]32,44,48,49 whereas three articles (21.43%) included patients with mild acne.…”

Section: R E Su Ltsmentioning

confidence: 99%

“…We identified five articles (36%) reporting means and standard deviations [28][29][30]32,44 and nine (64%), lacking this information. 27,33,[45][46][47][48][49][50][51] With regards to study design, most articles (i.e. 7%-50% 27,28,30,33,45,48,50 ) were cohort, six (42.86%) 29,32,44,46,49,51 were case-control, and one (7.14%) was a case report.…”

Section: R E Su Ltsmentioning

confidence: 99%

“…27,33,[45][46][47][48][49][50][51] With regards to study design, most articles (i.e. 7%-50% 27,28,30,33,45,48,50 ) were cohort, six (42.86%) 29,32,44,46,49,51 were case-control, and one (7.14%) was a case report. 47 Treatment monitoring was the focus of six studies (43%), 28,33,[46][47][48][49] while the remaining 8 (57%) characterized acne lesions, unaffected skin in acne patients or both.…”

Section: R E Su Ltsmentioning

confidence: 99%

“…Of the nine articles missing means and standard deviation, 5 (56%) examined the infundibulum size. [46][47][48][49]51 Two studies (22%) described this feature as present or absent, without exact size specification. 46,47 One article (11%) reported the percentage of patients with small or large infundibula, however, without specifying the exact categories.…”

Section: Infundibulum Sizementioning

confidence: 99%

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The role of in vivo reflectance confocal microscopy for the management of acne: A systematic review

Cretu

Papachatzopoulou

Dascălu

et al. 2023

Acad Dermatol Venereol

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Acne diagnosis, severity assessment and treatment follow‐up rely primarily on clinical examination. In vivo reflectance confocal microscopy (RCM) provides non‐invasively, real‐time images of skin lesions with a level of detail close to histopathology. This systematic literature review aims to provide an overview of RCM utility in acne and a summary of specific features with clinical application that may increase objectivity in evaluating this condition. We used the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines for reporting our results. We systematically searched three databases: PubMed, Clarivate and Google Scholar (January 2022). All included studies used RCM to investigate acne in human patients and reported the investigated skin area and type (acne lesions or clinically uninvolved skin), the substance used in the case of treatment. Our search identified 2184 records in the three databases investigated. After duplicate removal, 1608 records were screened, 35 were selected for full‐text assessment, and 14 were included in this review. We used the QUADAS‐2 tool to evaluate the risk of bias and applicability concerns. RCM was selected as the index test and clinical examination as the reference standard. The total number of patients from all studies was 291, with 216 acne patients and 60 healthy participants aged between 13 and 45 years. The 14 considered studies analysed 456 follicles from healthy participants, 1445 follicles from uninvolved skin in acne patients and 1472 acne lesions. Consistent RCM findings concerning follicles of acne patients reported across studies were increased follicular infundibulum size, thick, bright border, intrafollicular content and inflammation. Our analysis indicates that RCM is a promising tool for acne evaluation. Nevertheless, standardization, a unified terminology, consistent research methods and unitary reporting of RCM findings are necessary. PROSPERO registration number CRD42021266547.

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