Comparative study of intrauterine infusion of autologous platelet rich plasma in unresponsive thin endometrium in frozen ET cycle

Godha, Zeepee; Nayar, Kanad Dev; Singh, Meenal; Gupta, Shweta; Gupta, Monica; Mittal, Princy

doi:10.4103/fsr.fsr_22_19

Fertil Sci Res

2019

DOI: 10.4103/fsr.fsr_22_19

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Comparative study of intrauterine infusion of autologous platelet rich plasma in unresponsive thin endometrium in frozen ET cycle

Zeepee Godha

Kanad Dev Nayar

Meenal Singh

et al.

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2023

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“…Trial sequential analysis for (F) clinical pregnancy in Thin Endometrium (TE) studies; Table S3: Summary of the quality assessment by GRADE approach of outcomes included in the meta-analysis of Repeated Implantation Failure patients; Table S4: Summary of the quality assessment by GRADE approach of outcomes included in the meta-analysis of Thin Endometrium patients. References [ 104 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 ] are cited in the supplementary materials.…”

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Efficacy of Platelet-Rich Plasma in Women with a History of Embryo Transfer Failure: A Systematic Review and Meta-Analysis with Trial Sequential Analysis

et al. 2023

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Assisted reproductive technology (ART) is used to enhance pregnancy in infertile women. In this technique, the eggs are removed from the ovary and fertilized and injected with sperm to make embryos. Unfortunately, embryo implantation failures still occur in many of these women. Platelet-rich plasma (PRP) therapies use a patient’s own platelets to promote tissue healing and growth, including endometrium. The growth factors provided by the platelets play a criterial role on the regenerative ability of PRP. In the last years, PRP treatments have been gaining a lot of popularity to treat women with repeated ART failures. In this study, we collected and summarized all information published in the scientific literature to assess the evidence of the PRP effect on pregnancy. We only considered randomized controlled trials (RCT), a type of study designed to be unbiased and considered at the highest level of evidence. Our analysis indicates that PRP therapies might be an effective treatment in cases of poor responsiveness to conventional ART. However, additional studies (well-designed) are necessary to confirm this beneficial effect of PRP.

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Efficacy of Platelet-Rich Plasma in Women with a History of Embryo Transfer Failure: A Systematic Review and Meta-Analysis with Trial Sequential Analysis

et al. 2023

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Comparative study of intrauterine infusion of autologous platelet rich plasma in unresponsive thin endometrium in frozen ET cycle

Cited by 1 publication

References 16 publications

Efficacy of Platelet-Rich Plasma in Women with a History of Embryo Transfer Failure: A Systematic Review and Meta-Analysis with Trial Sequential Analysis

Efficacy of Platelet-Rich Plasma in Women with a History of Embryo Transfer Failure: A Systematic Review and Meta-Analysis with Trial Sequential Analysis

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