Comparative studies on phytochemistry, antioxidant and antibacterial activity of direct and sequential extracts of chromolaena odorata leaves

K, Udaya Prakash N; Sriraman,; Shanmugasundaram, Devika; Peneena,; Sripriya, N; Srinivasan, Badrinarayanan; Balamurugan, S.

doi:10.26452/ijrps.v10i2.275

Cited by 7 publications

(4 citation statements)

References 27 publications

(29 reference statements)

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“…Salama et al, 2018 reprted that Dodonaea viscose leave extracts showed moderate to low activity against various tested pathogens (zone of inhibition in the range 7 -10 mm) whereas we found strong antibacterial activity in our study (30-9 mm). In this search, Staphylococcus aureus showed higher response for the extracts of D. viscose except chloroform extract and this report is similar to that of (Udaya prakash et al, 2012) 17 . But the record result for Bacillus subtilis is differ, as Udaya prakash et al found that B. subtilis was affected with all extracts we found n-butanol extract not influenced.…”

Section: Antimicrobial Activitysupporting

confidence: 89%

Phytochemical Study and Antimicrobial Activity of Two Medicinal Plants from Al-Baha Region

2019

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The plant is a huge therapeutic source with enormous applications in curative industry. For new sources of antimicrobial agents, chloroform, ethyl acetate, and n–butanol extracts of two medicinal plants (Dodonaea viscose and Capparis spinosa) were prepared by liquid – liquid extraction. The plants were collected from Shuda mountain / Al-Baha region/ Saudi Arabia and then evaluated systematically. Phytochemical screening tests detect the existence of flavonoids, alkaloids, tannin, terponoids, saponnins and carbohydrates in most of the performed extracts. Antimicrobial activity was assessed against five bacterial and one fungal race. The extracts of the two plants leaves showed wide vision antibacterial activity and significant antifungal activity. The antibacterial activity (zone of inhibition) of Dodonaea viscose species varied from 30 to 18 mm, whereas of Capparis spinosa the range from 20 to 16 mm for ethyl acetate extracts, for n- butanol extracts the inhibition zone differ from 15 – 10 and 16 - 10 mm respectively. These results indicated that antimicrobial activities of plant species differ to a wide range not only between species themselves but also within the tests for antimicrobial evaluation. The current result supports the medicinal use of the leaves of these studied plants which works as an antimicrobial agent. These results compare to other studies carried out for the same plants in different countries in different environments exhibited diverse outcome in chemical constituents in the plant extracts and in their effects on tested types of micro organismswhich may have been due to a number of factors, including geographical location, season and environmental factors, and the method of extraction. This study for the two plant species was first time performed in this area of Saudi Arabia.

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Section: Antimicrobial Activitysupporting

confidence: 89%

Phytochemical Study and Antimicrobial Activity of Two Medicinal Plants from Al-Baha Region

2019

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“…Among the solvents studied, all the secondary metabolites except for alkaloids were extracted highly in methanol when compared with chloroform. Yields of different phytochemicals from plant extracts are found to vary depending on the method of extraction and the solvent used (Udayaprakash et al, 2019).…”

Section: Discussionmentioning

confidence: 99%

Phytochemical composition and antioxidant activity of coconut cotyledon

Kannaian

Edwin²,

Rajagopal³

et al. 2020

Heliyon

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Coconut tree (Cocos nucifera L.), a perennial, monocot tree, belonging to the family Arecaceae, is distributed through the tropics. Bioactivities of coconut water, husk fiber, oil, flowers, spadix and mesocarp of coconut fruit are widely reported. However, there is no study on cotyledon of coconut. In this study, carbohydrates, proteins, lipids, phenols, flavonoids, tannins, alkaloids and antioxidants were quantified in hot and cold percolated extracts of coconut cotyledon. Further, the antioxidant activity was studied using 2,2-diphenyl-1-picrylhydrazyl (DPPH); ferric reducing antioxidant power (FRAP); ferric thiocyanate (FTC); thiobarbituric acid (TBA); nitric oxide (NO) radical scavenging and β-carotene bleaching assays. Among the secondary metabolites, only cardiac glycosides were detected. Methanolic extraction by cold percolation extracted high content of secondary metabolites and exhibited significant antioxidant activity in DPPH, FRAP, NO and β-carotene bleaching assays, with EC 50 of 0.12, 6.43, 16.21 and 8.09 mg/ml respectively. The chloroform extracts recorded high lipid content and scavenged the radicals in FTC (EC 50 13.31 mg/ml) and TBA (EC 50 9.21 mg/ml) assays. The study recommends extraction of compounds using methanol through cold percolation. The cotyledon of coconut is found to be a potent nutritive source equivalent to the endosperm.

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“…Pomegranate peel, which accounts for approximately 50% of the fruit weight, is distinguished by the presence of high molecular weight phenolics, ellagitannins, proanthocyanidins, complex polysaccharides, flavonoids, and significant amounts of microelements, all of which have anti-mutagenic, antioxidant, antimicrobial, and apoptotic properties (Dikmen et al, 2011;Li et al, 2006;Prakash et al, 2013;Ricci et al, 2006;Tezcan et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

Role of Punica granatum-derived nanosilver in helminth protection

Thagfan

Abdel‐Gaber

MAREY

et al. 2023

Food Sci. Technol (Campinas)

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Pomegranate is a long-known edible fruit with medicinal properties. Helminth infections are among the most common human illnesses worldwide, due to a lack of suitable sanitary systems and safe drinking water sources. Although these illnesses are seldom deadly, they cause development limitations in children, which damage their school performance and make them susceptible to other illnesses. The present study has been conducted to investigate the anthelmintic activity of silver nanoparticles (AgNPs) synthesized from Pomegranate peel extract (PPE-AgNPs). Also, the cytotoxicity of PPE-AgNPs was tested in liver (Huh7), colon (HCT116) and breast (MDA-MB 231) cancer lines. Three doses were used (5, 2.5 and 1.25 mg/ml) to study the anthelmintic activity of PPE-AgNPs. Eisenia fetida was used as a model worm. Also, Mebendazole was used as a reference drug. Phytochemical analysis using FT-IR showed the presence of 13 compounds. In all tests, a dose-dependent effectiveness was shown. The most efficient dose, 5mg/ml showed the time to paralysis and death were 8.118 ± 0.26 and 9.338 ± 0.14 min, respectively. In all treated worms, histological examination revealed significant malformation of surface architecture of worms. We conclude that PPE-AgNPs has strong anthelmintic properties and low cytotoxicity, stimulating its use in the biomedical field.

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Comparative studies on phytochemistry, antioxidant and antibacterial activity of direct and sequential extracts of chromolaena odorata leaves

Cited by 7 publications

References 27 publications

Phytochemical Study and Antimicrobial Activity of Two Medicinal Plants from Al-Baha Region

Phytochemical Study and Antimicrobial Activity of Two Medicinal Plants from Al-Baha Region

Phytochemical composition and antioxidant activity of coconut cotyledon

Role of Punica granatum-derived nanosilver in helminth protection

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