Comparative point prevalence survey of antimicrobial consumption between a hospital in Northern Ireland and a hospital in Jordan

El‐Hajji, Feras Darwish; Al-Taani, Ghaith; Anani, L.; Al-Masri, Sahar; Abdalaziz, Haneen; Qabba’h, Su’ad H.; Bawab, Abdel Qader Al; Scott, Michael; Farren, David; Gilmore, Fiona; Versporten, Ann; Goossens, Herman; Aldeyab, Mamoon A.

doi:10.1186/s12913-018-3656-y

Cited by 33 publications

(27 citation statements)

References 34 publications

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“…Similar to previous studies [ 24 , 25 ], a high proportion of broad-spectrum antibiotic prescribing for surgical prophylaxis was noticed for several types of surgeries for more than one day in the included wards. Prolonged surgical prophylaxis was also common in Southern and Eastern Europe (85%, 86.3% respectively) [ 17 , 18 ], although it does not prevent the development of postoperative infections.…”

Section: Discussionsupporting

confidence: 86%

Antimicrobial Consumption and Resistance in a Tertiary Care Hospital in Jordan: Results of an Internet-Based Global Point Prevalence Survey

et al. 2020

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Background: The Global Point Prevalence Survey (Global-PPS) provides a standardised method to conduct surveillance of antimicrobial prescribing and resistance at hospital level. The aim of the present study was to assess antimicrobial consumption and resistance in a Jordan teaching hospital as part of the Global-PPS network. Methods: Detailed antimicrobial prescription data were collected according to the Global Point Prevalence Survey protocol. The internet-based survey included all inpatients present at 8:00 am on a specific day in June–July 2018. Resistance data were based on microbiological results available on the day of the PPS. Results: Data were collected for 380 patients admitted to adult wards, 72 admitted children, and 36 admitted neonates. The overall prevalence of antimicrobial use in adult, paediatric, and neonatal wards was 45.3%, 30.6%, and 22.2% respectively. Overall, 36 patients (7.4%) were treated for at least one healthcare-associated infection (HAI). The most frequent reason for antimicrobial treatment was pneumonia. Cephalosporins and carbapenems were most frequent prescribed among adult (50.6%) and paediatric/neonatal wards (39.6%). Overall resistance rates among patients treated for a community or healthcare-associated infection was high (26.0%). Analysis of antibiotic quality indicators by activity revealed good adherence to treatment guidelines but poor documentation of the reason for prescription and a stop/review date in the notes. Conclusion: The present study has established baseline data in a teaching hospital regarding the quantity and quality of prescribed antibiotics in the hospital. The study should encourage the establishment of tailor-made antimicrobial stewardship interventions and support educational programs to enhance appropriate antibiotic prescribing.

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Section: Discussionsupporting

confidence: 86%

Antimicrobial Consumption and Resistance in a Tertiary Care Hospital in Jordan: Results of an Internet-Based Global Point Prevalence Survey

et al. 2020

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“…High adherence of prescriptions to the standard treatment guidelines in the current study (84.0%) is similar to previous studies in South Africa (98.0%), Northern Ireland (72.0%–81.8%), Jordan (92.2%–92.7%), Brazil (76.5%–87.3%) and Belgium (76.6%). 23–26 In contrast to these findings, a study in Nigeria found low adherence, ranging from 0.3% to 7.2%. 22 The finding of high adherence in Mbeya ZRH (94.0%), in contrast to the 63.0% found in 2018 by another study in the same hospital, may be accounted for by the possibility of postsurvey sensitisation and/or awareness.…”

Section: Discussionmentioning

confidence: 87%

Antimicrobial use across six referral hospitals in Tanzania: a point prevalence survey

et al. 2020

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ObjectiveTo delineate the prevalence and factors associated with antimicrobial use across six referral hospitals in Tanzania using WHO point prevalence survey (PPS) methodology to inform hospital-specific antimicrobial stewardship programmes.DesignCross-sectional analytical study.SettingSix referral hospitals in Tanzania.ParticipantsPatients irrespective of age and gender (n=948) admitted in the six referral hospital wards before 8:00 hours on each day of the survey were included in December 2019. Using the WHO PPS methodology, data on hospitals, wards, patients, antibiotics, and indications for antibiotics were collected.Outcome measuresWe analysed the prevalence of antibiotic use by referral hospital, ward, indication and patient characteristics as the main outcomes. We also described adherence to the Tanzania Standard Treatment Guidelines (STG) and WHO’s AWaRe categorisation of antibiotics.ResultsApproximately 62.3% of inpatients were prescribed antibiotics, predominantly from the Access group of antibiotics (ceftriaxone, metronidazole or ampicillin–cloxacillin). The overall adherence of antibiotic prescriptions to the Tanzania STG was high (84.0%), with the exception of Sekou Toure Regional Referral Hospital (68.0%) and Maweni Regional Referral Hospital (57.8%). The most common indication for antibiotic prescriptions was community-acquired infections (39.8%). Children less than 2 years of age (OR 1.73, 95% CI 1.02 to 2.92, p=0.039); admission to surgical wards (OR 4.90, 95% CI 2.87 to 8.36, p <0.001); and admission to paediatric wards (OR 3.93, 95% CI 2.16 to 7.15, p <0.001) were associated with increased odds of antibiotic use. Only 2 of 591 patients were prescribed antibiotics based on culture and antimicrobial susceptibility testing results.ConclusionsEmpirical use of antibiotics is common, and the Access group of antibiotics is predominantly prescribed in children less than 2 years and patients admitted to surgical and paediatric wards. Lack of utilisation of antimicrobial susceptibility testing services in these hospitals requires urgent interventions. Routine monitoring of antibiotic use is recommended to be part of antibiotic stewardship programmes in Tanzania.

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“…To identify inappropriate antibiotic prescribing, we investigated five indicators of quality, which could easily be used to set benchmarks for quality improvement of antibiotic use in hospitals. [8] In our study, diagnosis was mentioned in 83.11% ( n = 64) of prescriptions [Figure 1]. Documentation of the reason for prescription ensures communication of diagnosis and treatment among clinicians and other health-care providers, and allows for recording of prescription stop or review dates and other interventions such as de-escalation.…”

Section: Discussionmentioning

confidence: 94%

A pilot point prevalence study of antimicrobial drugs in indoor patients of a teaching hospital in Central India

Najmi

Sadasivam

Jhaj

et al. 2019

J Family Med Prim Care

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Aim: To evaluate the point prevalence of antimicrobial drug use by using point prevalence survey method. Methodology: A cross-sectional point prevalence study was done on patients admitted in AIIMS Bhopal hospital. This study included all inpatients receiving an antimicrobial that were on the ward at 8 AM on a specific day in May 2018. Information regarding age, gender, occupation, income group, diagnosis, patient's present/past medical history, treatment, any adverse drug reactions, and investigations are recorded in a pro forma. Results: A total of 77 patients (31.95%) were included out of total 241 patients who received at least one antimicrobial. Of patients who received at least one antimicrobial, diagnosis was mentioned in 83.11% of prescriptions. Targeted treatment was given to 10.38% of patients. Reasons for antimicrobial were recorded in 12.98% of patients. Most common healthcare infection recorded was catheter-associated urinary tract infections followed by postoperative surgical site infections. Penicillin with beta lactamase inhibitors was most commonly prescribed antibiotic group followed by third generation cephalosporins and fluoroquinolones. Stop or review date was recorded in 19.48% of patients. Parenteral administration was given to 30.55% of patients. Compliance to guidelines was followed in 64.11% of patients. Local antibiotic guideline and antibiogram were available in hospital. Biomarkers were utilized in 9.77% of patients to guide the choice of therapy. Conclusion: Availability of antibiotic policy, antibiogram, local antibiotic guidelines, drugs, and therapeutic committee were some of the encouraging findings. Diagnosis was mentioned in majority of prescriptions. Most patients were prescribed oral antimicrobial drugs, which can reduce complications with parenteral route. Underutilizations of microbiological facilities, prolonged use of antibiotics for surgical prophylaxis, and polypharmacy were areas of concern.

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Comparative point prevalence survey of antimicrobial consumption between a hospital in Northern Ireland and a hospital in Jordan

Cited by 33 publications

References 34 publications

Antimicrobial Consumption and Resistance in a Tertiary Care Hospital in Jordan: Results of an Internet-Based Global Point Prevalence Survey

Antimicrobial Consumption and Resistance in a Tertiary Care Hospital in Jordan: Results of an Internet-Based Global Point Prevalence Survey

Antimicrobial use across six referral hospitals in Tanzania: a point prevalence survey

A pilot point prevalence study of antimicrobial drugs in indoor patients of a teaching hospital in Central India

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