Comparative evaluation of Morinda citrifolia with chlorhexidine as antimicrobial endodontic irrigants and their effect on micro-hardness of root canal dentin:
An in vitro study

Prabhakar, A R; Basavraj, Priyanka; Basappa, N

doi:10.4103/2231-6027.122086

Cited by 19 publications

(21 citation statements)

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“…Using a diamond disc, two grooves; one on the buccal and one on the lingual external roots' surfaces were created under watercooling without penetration into the root-canals. Each root was then split longitudinally into two halves by a chisel (12,13).…”

Section: Introductionmentioning

confidence: 99%

A comparative ex-vivo study of effects of different irrigation protocols with/without laser activation on the root dentine’s micro-hardness

et al. 2019

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To compare the effects of different irrigation protocols, with/without laser activation, on the radicular dentine's micro-hardness. Methods: Eighty-two human extracted premolars were decoronated and divided into 7 groups. Roots were longitudinally split into two halves. The micro-hardness was measured for one half before and after irrigation protocols. The groups were; G1: MTAD without laser-activation, G2: MTAD with laser-activation, G3: sodiumhypochlorite (SH) with laser-activation, G4: SH then EDTA with laser-activation, G5: SH then MTAD with laseractivation, G6: SH without laser-activation. G7: distilled water (control). In the two-irrigants groups G4 and G5), samples were irrigated first with SH then with MTAD or EDTA irrigants, which were activated by the laser. The difference between the before-and after-irrigation micro-hardness was calculated to obtain the microhardness difference. Data were analyzed using the Paired Sample-t and Two-ways ANOVA tests at P=0.05. Results: Overall, the mean dentine's micro-hardness after-irrigation (103.1) was lower than before-irrigation (116.1) (P<0.001); except for the distilled-water group, (116.6 and 112.9, respectively) (P=0.075). The microhardness reduction of SH without laser-activation group (32.5) was the greatest (P<0.001). The single-irrigant or laser-activation irrigation protocols caused significantly less micro-hardness reduction compared to the two-irrigants or no laser-activation protocols. The mean micro-hardness reduction of SH and MTAD groups (both with laser-activation) (5.8 and 9.3, respectively) were significantly lower than other groups, but not from that of the control group (3.7). Conclusion:Using irrigants significantly reduced the root-dentine's micro-hardness. Although irrigants agitation by an Er: Yag laser significantly minimized micro-hardness reduction, it did not suppress the adverse effects on dentine micro-hardness when two-irrigants were used.

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Section: Introductionmentioning

confidence: 99%

A comparative ex-vivo study of effects of different irrigation protocols with/without laser activation on the root dentine’s micro-hardness

et al. 2019

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“…Very few studies [9][10][11][12][13] have been reported on antibacterial activity of Morinda Citrifolia juice on Enterococcus Faecalis (E. Faecalis), the effect of Ethanolic Extract of Morinda Citrifolia has yet not clearly identified. The present study was mainly aimed at evaluating the invitro antimicrobial efficacy of Novel Ethanolic Extract of Morinda Citrifolia by agar well diffusion and Broth dilution methods.…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial efficacy of Novel Ethanolic Extract of Morinda Citrifolia Against Enterococcus Feacalis by Agar Well Diffusion Method and Minimal Inhibitory Concentration- An Invitro Study.

Gummuluri¹,

Teja

Kaligotla

2019

BDS

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Introduction: the long term success of root canal treatment is ultimately related to the effective debridement and disinfection of the root canal system. Hence, the irrigants play an important role in achieving the good penetrability and bactericidal activity. The present study was mainly aimed at evaluating the invitro antimicrobial efficacy of Novel Ethanolic Extract of Morinda Citrifolia by agar well diffusion and minimal inhibitory concentration. Materials and Methods:the antimicrobial efficacy of the Novel Ethanolic Extract of Morinda Citrifolia was tested using agar well diffusion and minimal inhibitory concentration was assessed. The zone of inhibitions were determined at 10 mg/ml concentration of Ethanolic Extract of Morinda Citrifolia on agar well plate and Minimal Inhibitory Concentration (MIC) against tested microorganism. Results: results obtained in the present study by both qualitative and quantitative experiments revieled that the tested Ethanolic Extract of Morinda Citrifolia possesses potential antibacterial activity against Enterococcus Feacalis when compared with standard antibiotic tetracycline. the highest zone of inhibition of 15mm was showed at 1000micrograms by agar well diffusion assay. The optimal antimicrobial activity was seen at 250micrograms for Morinda Citrifolia against Enterococcus Feacalis.Conclusion: novel Ethanolic extract of Morinda Citrifolia has shown an optimal antimicrobial activity against E.Feaclais. But still, future studies are still needed.

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“…1 This goal can be accomplished using mechanical 10.5005/jp-journals-10015-1524 instrumentation and chemical irrigation, with medication of the root canal system between treatment sessions. 2 One should completely understand the microbio logy involved in the endodontic pathologies. Endodontic microbiology, such as Prevotella, Porphyromonas, Actinomyces spp., Propionibacterium propionicum, Parvimonas micra (previously called Peptostreptococcus micros or Micromonas micros), Streptococcus species, and Enterococcus faecalis are most often opportunistic pathogens.…”

Section: Introductionmentioning

confidence: 99%

Morindacitrifolia: A Fruit to Future Endodontics

Mookhtiar¹

2018

World Journal of Dentistry

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The aim of this article is to review Morinda citrifolia in the field of endodontics. Herbal medicaments have been used as remedies for various illnesses and diseases for centuries. Furthermore, it has been a topic of interest in dentistry for many years. Morinda citrifolia juice (MCJ), also commonly known as "Noni," a tropical fruit, has a wide range of uses in endodontics and in the eradication of endodontic pathogens without any potential side effects. A literature review is conducted using electronic databases, such as "PubMed," "Google Scholar," and "Scopus," using keywords "Herbal Medicine" and "M. citrifolia." Furthermore, an advanced or refined search was carried out using the keywords "Endodontics," "Root canal Therapy," "Irrigation," "Herbal Endodontics," and "Endodontic Disinfection." The MCJ can be used as an endodontic irrigant along with ethylenediaminetetraacetic acid (EDTA) as an adjuvant to sodium hypochlorite and chlorhexidine (CHX) due to its better smear layer removal properties and antimicrobial activity. It also does not have any major side effects as compared with sodium hypochlorite and CHX. It also helps in caries prevention and control, which is the main crux for the requirement for endodontic treatment. Further studies on MCJ on the endodontic aspect of dentistry can alter the chemical aspect of endodontic therapy in the near future. The MCJ, due to its advantages compared with sodium hypochlorite and CHX, can be used in the field of endodontics.

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Comparative evaluation of Morinda citrifolia with chlorhexidine as antimicrobial endodontic irrigants and their effect on micro-hardness of root canal dentin: An in vitro study

Cited by 19 publications

References 0 publications

A comparative ex-vivo study of effects of different irrigation protocols with/without laser activation on the root dentine’s micro-hardness

A comparative ex-vivo study of effects of different irrigation protocols with/without laser activation on the root dentine’s micro-hardness

Antimicrobial efficacy of Novel Ethanolic Extract of Morinda Citrifolia Against Enterococcus Feacalis by Agar Well Diffusion Method and Minimal Inhibitory Concentration- An Invitro Study.

Morindacitrifolia: A Fruit to Future Endodontics

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