Comparative evaluation of hemodynamic, vasoconstrictive, and SpO2variability during different stages of periodontal surgery performed using 0.5% ropivacaine or 2% lignocaine HCl (1:80,000 adrenaline) local anesthesia: A randomized, double-blind, split-mouth pilot study

Mishra, Ashank; Lalani, Zohra; Kalakonda, Butchibabu; Krishnan, Preeti; Pandey, Ruchi; Reddy, Krishnajaneya

doi:10.4103/jisp.jisp_18_18

Cited by 7 publications

(5 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The above study also supports our result that peri-tonsillar infiltration of ropivacaine with adrenaline is effective in reducing intraoperative bleeding. 16 A crucial result of our study was the decreased bleeding observed with ropivacaine peritonsillar infiltration when compared to the control group. Hence, we recommend the use of peri-tonsillar infiltration of ropivacaine (0.75%) in view of better management of intra-operative blood loss…”

Section: Discussionmentioning

confidence: 65%

A clinical study of effect of peri-tonsillar infiltration of ropivacaine on tonsillectomy haemorrhage

Ravi¹,

Naik²,

Nikethan³

et al. 2022

Int J Otorhinolaryngol Head Neck Surg

View full text Add to dashboard Cite

Background: The aim of this study to determine the relationship between the peritonsillar infiltration of ropivacaine hydrochloride and haemorrhage in patients undergoing tonsillectomy.Methods This prospective study was conducted in the department of otorhinolaryngology and head and neck surgery, Adichunchanagiri institute of medical sciences, B. G. Nagara, Mandya district. A sample size of 30 patients which satisfied the inclusion criteria were included in the study. Ropivacaine (0.75%) was locally infiltrated on the right side (R-side) in the peri-tonsillar region before the surgery. The left side was considered as the control side. Intra-operative blood loss was estimated separately for both the sides. The data from the study will be analysed using chi square test and Student t test technique.Results: The 17 (56.7%) females and 13 (43.3%) males participated in the study. Majority of the cases belonged to <10 years of age group. By analysing the data, blood loss was found to be higher on the left side (control side) compared to the right side on which peri-tonsillar infiltration of ropivacaine was given. The association between the blood loss on the right side and the left side (control side) was found to be significant (p<0.0001).Conclusions: Based on the result of our study it can be derived that the peri-tonsillar infiltration of Ropivacaine (0.75%) is very effective in reducing intra-operative bleeding and at the same time providing a better bloodless field during surgery. Hence, we recommend the use of peri-tonsillar infiltration of Ropivacaine (0.75%) in view of better management of intra-operative blood lossissn.2454-5929.ijohns20220041

show abstract

Section: Discussionmentioning

confidence: 65%

A clinical study of effect of peri-tonsillar infiltration of ropivacaine on tonsillectomy haemorrhage

Ravi¹,

Naik²,

Nikethan³

et al. 2022

Int J Otorhinolaryngol Head Neck Surg

View full text Add to dashboard Cite

show abstract

“…In studies by Reddy et al [ 4 ] and Mishra et al [ 11 ], the perioperative changes in heart rate and blood pressure were insignificant. Bansal et al [ 14 ] noted no statistically significant difference in the mean systolic and diastolic pressure values pre- and postoperatively 45 min after administration of 0.75% ropivacaine and 2% lignocaine with adrenaline, while the mean systolic blood pressure was increased in the ropivacaine and lignocaine groups.…”

Section: Discussionmentioning

confidence: 99%

“…After its commercial release, ropivacaine has been extensively used for perioperative pain relief in the medical field, with consistently better outcomes than other local anesthetic agents [ 4 ]. Its use in the dental discipline has expanded to studies on periodontic procedures to evaluate its anesthetic efficacy [ 11 ], topical anesthesia of the oral mucosa [ 12 ], simple extraction procedures [ 3 13 14 ], lower third molar surgeries[ 1 4 5 15 16 17 18 19 ], surgical removal of the upper third molars[ 20 ], surgical removal of chronic periapical lesions [ 21 ], oral aphthosis [ 22 ], mandibular osteotomy [ 23 ], and postoperative pain control after elective cleft palate repair in children [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

Clinical efficacy of 0.75% ropivacaine vs. 2% lignocaine hydrochloride with adrenaline (1:80,000) in patients undergoing removal of bilateral maxillary third molars: a randomized controlled trial

Kakade

Joshi

Naik

et al. 2021

J Dent Anesth Pain Med

View full text Add to dashboard Cite

Background Lignocaine with adrenaline is routinely used as a local anesthetic for dental procedures. Adrenaline was added to increase the duration of anesthesia. However, epinephrine containing a local anesthetic solution is not recommended in conditions such as advanced cardiovascular diseases and hyperthyroidism. Recently, ropivacaine has gained popularity as a long-acting anesthetic with superior outcomes. The goal of this study was to assess and compare the effectiveness of 0.75% ropivacaine alone and 2% lignocaine with adrenaline (1:80,000) in the removal of bilateral maxillary wisdom teeth using the posterior superior alveolar nerve block technique. Methods This was a single-blind, randomized, split-mouth, prospective study assessing 15 systemically sound outpatients who needed bilateral removal of maxillary third molars. We randomly allocated the sides and sequences of ropivacaine and lignocaine with adrenaline administration. We evaluated the efficacy of both anesthetics with regard to the onset of anesthesia, intensity of pain, variation in heart rate, and blood pressure. Results The onset of anesthesia was faster with lignocaine (138 s) than with ropivacaine (168 s), with insignificant differences (p = 0.001). There was no need for additional local anesthetics in the ropivacaine group, while in the lignocaine with adrenaline group, 2 (13.3%) patients required additional anesthesia. Adequate intraoperative anesthesia was provided by ropivacaine and lignocaine solutions. No significant difference was observed in the perioperative variation in blood pressure and heart rate. Conclusion Ropivacaine (0.75%) is a safe and an adrenaline-free local anesthetic option for posterior superior alveolar nerve block, which provides adequate intraoperative anesthesia and a stable hemodynamic profile for the removal of the maxillary third molar.

show abstract

“…Vasodilation results in the increased rate of absorption and reduced duration of action of anesthesia and consequently, increased anesthetic blood level and risk for toxicity. [ 9 10 11 ] Prilocaine is classified as the weakest powerful vasodilator. So, it can be useful for anesthetizing the patients who are prohibited from the use of local anesthetics with adrenaline.…”

Section: Introductionmentioning

confidence: 99%

“…[ 14 ] Felypressin is similar to oxytocin, and it can induce oxytocic action on the uterus. [ 10 12 ] Felypressin can also cause coronary artery vasoconstriction. So, felypressin is contraindicated in the late pregnancy stages and in patients with unstable angina and poorly controlled hemorrhage.…”

Section: Introductionmentioning

confidence: 99%

Does articaine, rather than prilocaine, increase the success rate of anaesthesia for extraction of maxillary teeth

Gazal

2020

Saudi J Anaesth

View full text Add to dashboard Cite

Objective: To compare the anesthetic performances of 3% prilocaine and 4% articaine when used for the extraction of the maxillary teeth. Materials and Methods: Ninety-five patients, aged between 16 and 70 years, were included in this study. Patients were divided into two groups. Group one received articaine 4% with 1:00.000 adrenaline. Group two received prilocaine with 3% felypressin (0.03 I.U. per ml). Onset time of anesthesia was objectively evaluated by using electronic pulp testing. Results: Eighty-five patients in this study had a successful local anesthetic followed by extraction within the study duration time (10 minutes). However, there were six patients with failure anesthesia (5 in prilocaine group and 1 in articaine group). By applying Person's Chi-square test (x2), there were no significant differences in the number of episodes of the anesthetic success between articaine and prilocaine groups at time intervals ( P = 0.5). T-test showed that there have been no important variations within the mean onset time of anesthesia for articaine and prilocaine buccal infiltrations ( P = 0.1). Conclusions: 3% Prilocaine with felypressin is as effective as 4% articaine with adrenaline when used for the extraction of maxillary teeth. Recommendations would be given to the dental practitioners to use prilocaine more frequently than articaine because of its low toxicity. Trial registration number: NCT04236115.

show abstract

Comparative evaluation of hemodynamic, vasoconstrictive, and SpO₂variability during different stages of periodontal surgery performed using 0.5% ropivacaine or 2% lignocaine HCl (1:80,000 adrenaline) local anesthesia: A randomized, double-blind, split-mouth pilot study

Cited by 7 publications

References 13 publications

A clinical study of effect of peri-tonsillar infiltration of ropivacaine on tonsillectomy haemorrhage

A clinical study of effect of peri-tonsillar infiltration of ropivacaine on tonsillectomy haemorrhage

Clinical efficacy of 0.75% ropivacaine vs. 2% lignocaine hydrochloride with adrenaline (1:80,000) in patients undergoing removal of bilateral maxillary third molars: a randomized controlled trial

Does articaine, rather than prilocaine, increase the success rate of anaesthesia for extraction of maxillary teeth

Contact Info

Product

Resources

About