Comparative Evaluation of Fluoride Release From Two Different Glass Ionomer Cement and a Novel Alkasite Restorative Material - An in Vitro Study

Singh, Harpreet; Acharya, Shashirashmi; Pai, Swathi; Kini, Sandya

doi:10.1590/pboci.2020.019

Cited by 9 publications

(13 citation statements)

References 11 publications

(13 reference statements)

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“…Alkasite materials contain alkaline fillers that release acid-neutralizing ions. In the mixed form of Cention N, the weight percentage of alkaline glass is around 24.6%, which is responsible for ion release [ 37 ].…”

Section: Discussionmentioning

confidence: 99%

Phosphate Ion Release and Alkalizing Potential of Three Bioactive Dental Materials in Comparison with Composite Resin

Kasraei

Haghi

Valizadeh

et al. 2021

International Journal of Dentistry

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Aim. Several new bioactive compounds were recently introduced to the market with favorable ion release, tooth remineralization, and alkalizing potential. This study sought to compare the phosphate ion release and alkalizing potential of three bioactive materials in comparison with composite resin. Methods. Thirty-six discs (2 × 6 mm) were fabricated from Fuji II LC resin modified glass ionomer (RMGI), Activa BioActive, Cention N, and Z250 composite in plastic molds. The specimens were stored in distilled water for 24 and 48 h and 6 months. Half of the specimens were used to assess the phosphate ion release while the other half were used to assess the alkalizing potential 1 h after pH drop from 6.8 to 4. Phosphate ion release was quantified by a spectrophotometer while the pH value was measured by a pH meter. Data were analyzed using two-way ANOVA, one-way ANOVA, and Tukey’s HSD test (for pairwise comparisons) at 0.05 level of significance. Results. At 24 h, the maximum phosphate ion release in distilled water occurred in the Fuji II LC group followed by Cention N, Activa BioActive, and Z250. At 6 months, Cention N followed by Activa BioActive showed higher phosphate ion release than Fuji II LC and Z250. No significant difference was noted between Activa BioActive and Cention N at any time point. All materials, except for Z250, increased the pH of the environment. Fuji II LC had maximum alkalizing effect at all time points followed by Cention N and Activa BioActive. Conclusion. Use of bioactive compounds is a promising method to ensure phosphate ion release, and can have a positive effect on tooth remineralization over time. Also, bioactive compounds can alkalize an acidic environment.

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Section: Discussionmentioning

confidence: 99%

Phosphate Ion Release and Alkalizing Potential of Three Bioactive Dental Materials in Comparison with Composite Resin

Kasraei

Haghi

Valizadeh

et al. 2021

International Journal of Dentistry

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“…Various factors such as the fluoride amount present in the cement, powder-liquid ratio, and the capacity for water diffusion in the materials affect fluoride release [17,18]. In this study, the amount of fluoride released from ARM was significantly higher than that from giomer.…”

Section: ⅳ Discussionmentioning

confidence: 53%

Assessment of Fluoride Release through Dentin Adhesive in the Alkasite Restorative Material and Giomer

Kim¹,

Park²,

Lee³

et al. 2021

THE JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY

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This study evaluated the fluoride release of alkasite restorative material (ARM) and giomer penetrating the dentin adhesive layer. Twenty specimens were prepared for each restorative material, and dentin adhesive with uniform thickness was applied to half of them. The prepared specimens were placed in a polyethylene tube containing 2.0 mL of deionized water and deposited in a 37.0°C water bath for the study duration. The amount of fluoride release was measured on the 1st, 3rd, 7th, 14th, 21st, and 28th days after deposition. The dentin adhesive applied to the ARM and giomer could not completely block the fluoride release; however, it significantly reduced its amount. The cumulative amount of fluoride release of the ARM after 28 days was higher than that of the giomer regardless of the application of dentin adhesive.

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“…It could be because light-cured polymerization results in a more tightly bound or less hydrophilic matrix, and a low pH solution induces more rapid degradation of glass filler and ion release when compared to a neutral solution [ 10 , 25 ]. Several studies have shown that CN can release fluoride ions over long periods of time resulting in high fluoride accumulation [ 10 , 25 , 26 , 28 ]. As a result, the amount of fluoride released is likely to be affected by the immersion time.…”

Section: Discussionmentioning

confidence: 99%

“…As a result, the amount of fluoride released is likely to be affected by the immersion time. CN has the ability to release fluoride ions, similar to conventional GIC and resin-modified glass-ionomer cement (RMGIC), nevertheless a difference in amount and pattern of fluoride ion release were found in a previous study [ 28 ]. Singh’s study [ 28 ] showed that conventional GIC and RMGIC released the highest fluoride ions in day 1 due to the burst effect, and the fluoride release gradually decreased over time.…”

Section: Discussionmentioning

confidence: 99%

“…CN has the ability to release fluoride ions, similar to conventional GIC and resin-modified glass-ionomer cement (RMGIC), nevertheless a difference in amount and pattern of fluoride ion release were found in a previous study [ 28 ]. Singh’s study [ 28 ] showed that conventional GIC and RMGIC released the highest fluoride ions in day 1 due to the burst effect, and the fluoride release gradually decreased over time. However, CN released the least fluoride ions in day 1 and significantly more fluoride than conventional GIC and RMGIC at all other time periods.…”

Section: Discussionmentioning

confidence: 99%

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The impact of an alkasite restorative material on the pH of Streptococcus mutans biofilm and dentin remineralization: an in vitro study

2022

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Background It has been claimed that an alkasite restorative material can neutralize acids produced by cariogenic bacteria from released hydrogen ions and enable to remineralization via calcium and fluoride ions. However, there is no evidence to support this assertion. Therefore, the aims of this study were to investigate the effect of the alkasite restorative material on the pH of Streptococcus mutans biofilm and dentin hardness. Methods Streptococcus mutans biofilms were formed on Filtek™ Z350 (FZ, a resin composite) and Cention® N (CN, the alkasite restorative material) and their pH determined after 24 h. Hydroxide, fluoride, and calcium-ions released from the materials were determined at 6 h, 1, 3, 7, 14, and 28 days. Dentin specimens were prepared from 14 human molars and divided into four quadrants. Quadrant 1 was a sound dentin control, quadrants 2–4 were chemically demineralized, and a cylinder of FZ and CN placed on the surfaces of quadrants 2 and 4, respectively. The microhardness of quadrants 1 and 3 were measured at depths of 20, 40, and 60 µm from the occlusal surface, and similarly of quadrants 2 and 4, after 30 days. Independent t-test, Mann–Whitney-U, and repeated-measure-ANOVA were used for data analysis. Results The pH of biofilm on CN (4.45) was significantly higher (p < 0.05) than that on FZ (4.06). The quantity of all ions released from CN was significantly higher than from FZ. The hardness of demineralized dentin under CN was significantly higher than that of demineralized dentin at all depths, and higher than that of demineralized dentin under FZ at 20 and 40 µm. Conclusions CN released hydroxide, fluoride, and calcium ions, which was associated with raising the biofilm pH and the hardness of demineralized dentin. All results indicated that CN had the potential to reduce the incidence of secondary caries.

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Comparative Evaluation of Fluoride Release From Two Different Glass Ionomer Cement and a Novel Alkasite Restorative Material - An in Vitro Study

Cited by 9 publications

References 11 publications

Phosphate Ion Release and Alkalizing Potential of Three Bioactive Dental Materials in Comparison with Composite Resin

Phosphate Ion Release and Alkalizing Potential of Three Bioactive Dental Materials in Comparison with Composite Resin

Assessment of Fluoride Release through Dentin Adhesive in the Alkasite Restorative Material and Giomer

The impact of an alkasite restorative material on the pH of Streptococcus mutans biofilm and dentin remineralization: an in vitro study

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