Comparative evaluation for controlling release of niacin from protein- and cellulose-chitosan based hydrogels

Hanna, Demiana H.; Lotfy, Vivian F.; Basta, Altaf H.; Saad, Gamal R.

doi:10.1016/j.ijbiomac.2020.02.056

Cited by 67 publications

(25 citation statements)

References 55 publications

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“…Due to their characteristic feature as biodegradable materials, which address and minimize the environmental problems resulting from synthetic materials, their application increased in the last decades. They succeeded in producing functional products (e.g., advanced carbon nanostructures materials for water puri cation, semiconductor, optical materials, functional paper, low toxicity wood adhesives, food and hydrogels for medical and agricultural applications [1][2][3][4][5][6][7][8][9] Lignin is the second most abundant biopolymer and the main source of aromatic structures on earth. It contains an array of functional groups, such as aromatic and aliphatic hydroxyl, carbonyl, and methoxy groups, which imparts su cient reactivity with various compounds.…”

Section: Introductionmentioning

confidence: 99%

WITHDRAWN: Valorization of Biomass Pulping Waste As Effective Additive For Enhancing The Performance of Liquid Crystal Hydroxypropyl Cellulose Nanocomposite Film

Basta

Lotfy

Salem

2021

Preprint

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Utilization of wastes from some biomass-based industries in production of nanomaterials is vital in the green chemistry field. This work deals with valorization of lignin from paper making by-product for synthesizing lignin nanoparticles (LNPs) and evaluating its role on performance of hydroxypropyl cellulose (HPC) film as liquid crystal nanocomposite development, in comparison with different carbon nanoallotropes. In this respect LNPs, graphene oxide (GO) and bagasse-based carbon quantum dots (CQD) and carbon oxide (CO) were synthesized and incorporated with HPC during film formation. The effective behavior of LNPs, especially that produced from using highly polar solvent (PEG), on performance of HPC film was evidenced, from examining polarized light microscope together with TEM, SEM, XRD, FTIR, TGA as well as mechanical tests. The results showed that LNPs provided the HPC-nanocomposite film with acceptable thermal stability and mechanical properties, together with distinct complex mixed colorful texture, lines nearly like Grandjean-Cano lines aligned (PO images) and the planar layered morphology.

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Section: Introductionmentioning

confidence: 99%

WITHDRAWN: Valorization of Biomass Pulping Waste As Effective Additive For Enhancing The Performance of Liquid Crystal Hydroxypropyl Cellulose Nanocomposite Film

Basta

Lotfy

Salem

2021

Preprint

Self Cite

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“…Therefore, the result of in vitro experiment merely has a limited reference value. Also, some hydrogel‐based DDS could not maintain the sustained localized drug concentration, one reason lies in the burst release effect at the primary implantation stage 203 . Simultaneously, the unpredicted enzyme degradation effect, cell penetration, blood or interstitial fluid exchange, and body movement can also complicate the assessment.…”

Section: Discussionmentioning

confidence: 99%

Advances and trends of hydrogel therapy platform in localized tumor treatment: A review

Tan

Huang

et al. 2020

J Biomedical Materials Res

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Due to limitations of treatment and the stubbornness of infiltrative tumor cells, the outcome of conventional antitumor treatment is often compromised by a variety of factors, including severe side effects, unexpected recurrence, and massive tissue loss during the treatment. Hydrogel‐based therapy is becoming a promising option of cancer treatment, because of its controllability, biocompatibility, high drug loading, prolonged drug release, and specific stimuli‐sensitivity. Hydrogel‐based therapy has good malleability and can reach some areas that cannot be easily touched by surgeons. Furthermore, hydrogel can be used not only as a carrier for tumor treatment agents, but also as a scaffold for tissue repair. In this review, we presented the latest researches in hydrogel applications of localized tumor therapy and highlighted the recent progress of hydrogel‐based therapy in preventing postoperative tumor recurrence and improving tissue repair, thus proposing a new trend of hydrogel‐based technology in localized tumor therapy. And this review aims to provide a novel reference and inspire thoughts for a more accurate and individualized cancer treatment.

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“…The molecular weight of KGM directly affects the properties of its composite hydrogels. Studies have shown that oxidized KGM (OKG) with high‐molecular weight can enhance the cross‐linking degree of its composite hydrogels and show excellent self‐healing ability 109 . In addition, KGM is an ideal drug formulation for the treatment of dysphagia on its own merits.…”

Section: Products and Applicationsmentioning

confidence: 99%

Konjac glucomannan: A review of structure, physicochemical properties, and wound dressing applications

Zhou

Zheng

Xie

et al. 2021

J of Applied Polymer Sci

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Natural bio‐based materials used in wound dressings have been continuously developed in recent years, and have certain advantages in water retention, biocompatibility, and therapeutic properties. Konjac glucomannan (KGM) is a kind of plant polysaccharide with good cell compatibility and gel properties. Various gels obtained by modification of KGM through physical and chemical methods have great application potential in wound excipients. In the past few years, various KGM‐based wound barrier materials such as hydrogels, xerogel, microspheres, films, and fibers have been continuously researched and developed. The combination of KGM and other polymers can improve the problem of poor mechanical properties and give it new functional properties, which is beneficial to the moisturizing of the wound surface and the release of drugs to promote wound healing. This article reviews the physicochemical properties of KGM and the latest developments in KGM‐based composite gels, reveals the relationship between molecules in KGM‐based composite gels, and looks forward to the research and development prospects of KGM‐based composites in wound dressings.

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Comparative evaluation for controlling release of niacin from protein- and cellulose-chitosan based hydrogels

Cited by 67 publications

References 55 publications

WITHDRAWN: Valorization of Biomass Pulping Waste As Effective Additive For Enhancing The Performance of Liquid Crystal Hydroxypropyl Cellulose Nanocomposite Film

WITHDRAWN: Valorization of Biomass Pulping Waste As Effective Additive For Enhancing The Performance of Liquid Crystal Hydroxypropyl Cellulose Nanocomposite Film

Advances and trends of hydrogel therapy platform in localized tumor treatment: A review

Konjac glucomannan: A review of structure, physicochemical properties, and wound dressing applications

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