Comparative B‐mode and Doppler renal ultrasonography with histopathological findings in dogs positive for canine visceral leishmaniasis

Abstract

Morphological parameters and renal flow were assessed and measured in six clinically healthy dogs with negative serological and parasitological examinations for canine visceral leishmaniasis (CVL) and six dogs with CVL-positive serological and parasitological tests and asymptomatic condition of the disease. Kidney length and diameter were measured and compared with the aorta/kidney ratio. Alterations in flow were measured using the flow velocity (cm/s) and resistance index (RI). Renal function was assessed by serum biochemical examination (urea, creatine, total proteins, albumin, and globulin) and urinalysis. CVL-positive animals presented heterogeneous kidney echotexture, reduced vascular flow, hypoperfusion, lesser visualization of the arcuate arteries, high RI values (1.06 ± 0.28 for the right kidney and 1.10 ± 0.30 for the left kidney), reduced diastolic flow, and high systolic peak. They also presented positive creatine/RI correlation and between the renal artery vascular flow and kidney diameter. Histopathological analysis of CVL-positive animals was compatible and confirmed hemodynamic changes observed by Doppler ultrasound. The findings in the present study showed that Doppler ultrasonography is a valid method to assess and detect alterations in flow in renal pathological processes with kidney vascular damage, as in the case of leishmaniasis, and can help in the diagnosis of animals with this infection. Microsc. Res. Tech. 79:637-645, 2016. © 2016 Wiley Periodicals, Inc.

Determination of renal blood flow with Doppler ultrasound and the hypertension prevalence and acid-base level in dogs with chronic renal failure

“…A positive correlation between creatinine levels and RI and PI was reported in a study on patients with CRF in human medicine (Peterson et al, 1997). In addition, Baltazar et al (2016) and Torroja (2007), found a positive correlation between these parameters in cats and dogs. In the study of dogs managed in 1996, renal diseases were compared with the RI value and it was reported that there was no correlation between RI value and urea and creatinine (Morrow et al, 1996).…”

Aplicación de la imagenología a la clínica del aparato urogenital canino = Application of imaging to the clinic of the urogenital canine apparatus

“…Por todo lo expuesto hasta aquí, hemos querido contribuir con nuestro trabajo al desarrollo de la metodología encaminada a la predicción y prevención de la enfermedad renal crónica en la especie canina, fundamentando nuestra pretensión en los hallazgos publicados en diversos trabajos que hemos encontrado durante la labor de consulta bibliográfica, en los que puede observarse como se relacionan varios marcadores, unos con otros, para la determinación del daño renal (Watson et al, 2002;El-Khoury et al, 2016), o dichos marcadores en conjunto con otro tipo de pruebas diagnósticas de patología renal o cardiaca (Bacic et al, 2010), y como se analizan las diferencias entre los distintos tipos de procedimientos de diagnóstico por imagen o el valor predictivo de cada uno de ellos por separado (D´Anjou et al, 2011;Lobacz et al, 2012;Baltazar et al, 2016).…”